Site-specific antibody drug conjugates for cancer therapy (Q37593705)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24423619%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

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8 February 2021

Site-specific antibody drug conjugates for cancer therapy (English)

1 reference

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5 March 2020

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27 September 2019

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13 December 2019

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24 July 2020

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PubMed publication ID

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26 October 2020

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24 January 2021

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8 February 2021

antibody-drug conjugate

object of statement has role

subject heading

object named as

antibody drug conjugate

1 reference

PubMed publication ID

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24423619%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Siler Panowski

1 reference

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5 March 2020

Sunil Bhakta

series ordinal

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5 March 2020

Helga Raab

series ordinal

1 reference

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5 March 2020

Paul Polakis

series ordinal

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publication date

1 January 2014

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5 March 2020

published in

Monoclonal Antibodies

13 references

3 April 2019

25 June 2019

27 September 2019

11 November 2019

13 November 2019

27 November 2019

13 December 2019

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1 June 2020

24 July 2020

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issue

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page(s)

34-45

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Creative Commons Attribution-NonCommercial 3.0 Unported

5 March 2020

12 references

3 April 2019

25 June 2019

27 September 2019

11 November 2019

13 November 2019

27 November 2019

13 December 2019

1 June 2020

24 July 2020

26 October 2020

24 January 2021

on focus list of Wikimedia project

8 February 2021

ScienceSource

0 references

cites work

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23 August 2017

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Delivering cytokines at tumor site: The immunocytokine-conjugated anti-EDB-fibronectin antibody case.

23 August 2017

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Engineered therapeutic antibodies with improved effector functions

23 August 2017

1 reference

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Site specific conjugation of fluoroprobes to the remodeled Fc N-glycans of monoclonal antibodies using mutant glycosyltransferases: application for cell surface antigen detection

23 August 2017

1 reference

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Potent antibody drug conjugates for cancer therapy

23 August 2017

1 reference

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Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate

23 August 2017

1 reference

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A history of cancer chemotherapy

23 August 2017

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Targeted antimicrobial activity of a specific IgG-SMAP28 conjugate against Porphyromonas gingivalis in a mixed culture

23 August 2017

1 reference

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Antibody-drug conjugates for cancer therapy

23 August 2017

1 reference

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Targeted cancer therapy: conferring specificity to cytotoxic drugs

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Introducing genetically encoded aldehydes into proteins

23 August 2017

1 reference

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shRNA and siRNA delivery to the brain

23 August 2017

1 reference

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Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Size matters: a view of selenocysteine incorporation from the ribosome

23 August 2017

1 reference

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Arming antibodies: prospects and challenges for immunoconjugates

23 August 2017

1 reference

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Drug-conjugated monoclonal antibodies for the treatment of cancer

23 August 2017

1 reference

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Substrate-induced conformational changes in glycosyltransferases

23 August 2017

1 reference

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Paul Ehrlich's magic bullets

23 August 2017

1 reference

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Properties and applications of microbial transglutaminase

23 August 2017

1 reference

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Characterization of mammalian selenoproteomes.

23 August 2017

1 reference

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Addition of the keto functional group to the genetic code of Escherichia coli.

23 August 2017

1 reference

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Structure-based design of beta 1,4-galactosyltransferase I (beta 4Gal-T1) with equally efficient N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity

23 August 2017

1 reference

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Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation

23 August 2017

1 reference

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Mylotarg: antibody-targeted chemotherapy comes of age.

23 August 2017

1 reference

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Understanding and exploiting nature's chemical arsenal: the past, present and future of calicheamicin research.

23 August 2017

1 reference

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Phase I trial of the anti-Lewis Y drug immunoconjugate BR96-doxorubicin in patients with lewis Y-expressing epithelial tumors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

CC-1065 and the duocarmycins: unraveling the keys to a new class of naturally derived DNA alkylating agents

23 August 2017

1 reference

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Antibody-drug conjugates in cancer therapy

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Real-time quantification of antibody-short interfering RNA conjugate in serum by antigen capture reverse transcription-polymerase chain reaction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Differential effects of predosing on tumor and tissue uptake of an 111In-labeled anti-TENB2 antibody-drug conjugate.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Therapeutic potential of amanitin-conjugated anti-epithelial cell adhesion molecule monoclonal antibody against pancreatic carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Antibody-radionuclide conjugates for cancer therapy: historical considerations and new trends

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

The development of pyrrolobenzodiazepines as antitumour agents

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Engineered thio-trastuzumab-DM1 conjugate with an improved therapeutic index to target human epidermal growth factor receptor 2-positive breast cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Homo-oligomerization of the porcine reproductive and respiratory syndrome virus nucleocapsid protein and the role of disulfide linkages

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Potent antitumor activity of the anti-CD19 auristatin antibody drug conjugate hBU12-vcMMAE against rituximab-sensitive and -resistant lymphomas

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Phase I clinical comparative study of monoclonal antibody KS1/4 and KS1/4-methotrexate immunconjugate in patients with non-small cell lung carcinoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Site-specific and stoichiometric modification of antibodies by bacterial transglutaminase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Structural characterization of the maytansinoid-monoclonal antibody immunoconjugate, huN901-DM1, by mass spectrometry

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Construction and expression of antibody-tumor necrosis factor fusion proteins

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Carbohydrate-binding protein 35 (Mac-2), a laminin-binding lectin, forms functional dimers using cysteine 186.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

PK assays for antibody-drug conjugates: case study with ado-trastuzumab emtansine

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Impact of drug conjugation on pharmacokinetics and tissue distribution of anti-STEAP1 antibody-drug conjugates in rats

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Gemtuzumab Ozogamicin: One Size Does Not Fit All—The Case for Personalized Therapy

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Site-specifically 89Zr-labeled monoclonal antibodies for ImmunoPET.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

An enhanced system for unnatural amino acid mutagenesis in E. coli

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Antibody-drug conjugates for the treatment of non-Hodgkin's lymphoma: target and linker-drug selection

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Genetic incorporation of unnatural amino acids into proteins in mammalian cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929453

Location matters: site of conjugation modulates stability and pharmacokinetics of antibody drug conjugates

1 September 2018

1 reference

12 December 2020

Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates

1 reference

12 December 2020

Monoclonal antibody successes in the clinic

1 reference

12 December 2020

The pharmacologic basis for antibody-auristatin conjugate activity

1 reference

12 December 2020

Randomized phase II study of BR96-doxorubicin conjugate in patients with metastatic breast cancer

1 reference

12 December 2020

Maytansine, a novel antileukemic ansa macrolide from Maytenus ovatus

1 reference

12 December 2020

Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate

1 reference

12 December 2020

The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma

1 reference

12 December 2020

Expression of genetically engineered immunoconjugates of lymphotoxin and a chimeric anti-ganglioside GD2 antibody

1 reference

12 December 2020

Development of potent monoclonal antibody auristatin conjugates for cancer therapy

1 reference

12 December 2020

Design, synthesis and evaluation of bouvardin, deoxybouvardin and RA-I-XIV pharmacophore analogs

1 reference

12 December 2020

Antimitotic Activity of the Potent Tumor Inhibitor Maytansine

1 reference

12 December 2020

Identifiers

DOI

10.4161/MABS.27022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24423619%20AND%20SRC:MED&resulttype=core&format=json

release_o6wxh2wgq5cw3ggkgvzjhwfz6e

5 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/o6wxh2wgq5cw3ggkgvzjhwfz6e

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24423619%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

24423619

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24423619%20AND%20SRC:MED&resulttype=core&format=json