A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding. (Q37440613)

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scientific article published on 13 October 2009

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English	A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding.	scientific article published on 13 October 2009

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scholarly article

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9 February 2020

A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding (English)

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9 February 2020

DNA methylation

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Keith D. Robertson

10

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9 February 2020

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Suhasni Gopalakrishnan

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9 February 2020

Beth O Van Emburgh

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9 February 2020

Jixiu Shan

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9 February 2020

Zhen Su

4

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9 February 2020

C Robert Fields

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9 February 2020

Johannes Vieweg

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9 February 2020

Takashi Hamazaki

7

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9 February 2020

Philip H Schwartz

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9 February 2020

Naohiro Terada

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9 February 2020

publication date

13 October 2009

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9 February 2020

Molecular Cancer Research

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9 February 2020

7

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9 February 2020

10

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9 February 2020

1622-1634

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9 February 2020

DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions

1 reference

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23 August 2017

Aberrant RNA splicing and its functional consequences in cancer cells

1 reference

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23 August 2017

Vezf1 regulates genomic DNA methylation through its effects on expression of DNA methyltransferase Dnmt3b

1 reference

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23 August 2017

Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing

1 reference

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23 August 2017

Insights into the connection between cancer and alternative splicing

1 reference

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23 August 2017

DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function.

1 reference

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23 August 2017

Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

1 reference

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23 August 2017

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

1 reference

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Phenotypic plasticity and the epigenetics of human disease

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23 August 2017

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

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23 August 2017

Immunodeficiency, centromeric region instability, facial anomalies syndrome (ICF)

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23 August 2017

EUKARYOTIC CYTOSINE METHYLTRANSFERASES

1 reference

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23 August 2017

The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin

1 reference

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23 August 2017

DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783805

23 August 2017

Interactions within the mammalian DNA methyltransferase family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783805

23 August 2017

The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783805

23 August 2017

Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis

1 reference

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23 August 2017

An essential role for DNA methyltransferase DNMT3B in cancer cell survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783805

23 August 2017

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783805

23 August 2017

The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783805

23 August 2017

Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene

1 reference

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23 August 2017

The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783805

23 August 2017

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783805

23 August 2017

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783805

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Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

1 reference

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A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

1 reference

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23 August 2017

Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins

1 reference

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6 September 2017

Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements

1 reference

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cDNA fingerprinting of osteoprogenitor cells to isolate differentiation stage-specific genes.

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14 September 2017

A novel DNMT3B subfamily, DeltaDNMT3B, is the predominant form of DNMT3B in non-small cell lung cancer.

1 reference

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Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.

1 reference

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Preferential methylation of unmethylated DNA by Mammalian de novo DNA methyltransferase Dnmt3a.

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Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus

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Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation.

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Expression of mRNA for DNA methyltransferases and methyl-CpG-binding proteins and DNA methylation status on CpG islands and pericentromeric satellite regions during human hepatocarcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19825994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-satellite DNA methylation in normal individuals and in ICF patients: heterogeneous methylation of constitutive heterochromatin in adult and fetal tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/19825994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypomethylation of pericentromeric DNA in breast adenocarcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/19825994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19825994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1541-7786.MCR-09-0018

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9 February 2020

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9 February 2020

PubMed publication ID

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9 February 2020

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