Tyrosine capsid-mutant AAV vectors for gene delivery to the canine retina from a subretinal or intravitreal approach (Q37432588)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24225638%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Tyrosine capsid-mutant AAV vectors for gene delivery to the canine retina from a subretinal or intravitreal approach (English)

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29 February 2020

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29 February 2020

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29 February 2020

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29 February 2020

Simon M Petersen-Jones

series ordinal

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29 February 2020

A Dinculescu

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29 February 2020

S L Boye

series ordinal

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29 February 2020

J T Bartoe

series ordinal

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29 February 2020

language of work or name

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14 November 2013

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29 February 2020

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29 February 2020

volume

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29 February 2020

issue

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29 February 2020

page(s)

96-105

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Retinal Thickness Normative Data in Wild-Type Mice Using Customized Miniature SD-OCT.

29 February 2020

cites work

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Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors

23 August 2017

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Evaluation of lateral spread of transgene expression following subretinal AAV-mediated gene delivery in dogs

23 August 2017

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Optimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold?

23 August 2017

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Intravitreal injections at the Massachusetts Eye and Ear Infirmary: analysis of treatment indications and postinjection endophthalmitis rates.

23 August 2017

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A comprehensive review of retinal gene therapy

23 August 2017

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Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement

23 August 2017

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Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells.

23 August 2017

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23 August 2017

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Restoration of vision in the pde6β-deficient dog, a large animal model of rod-cone dystrophy

23 August 2017

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Tyrosine-mutant AAV8 delivery of human MERTK provides long-term retinal preservation in RCS rats.

23 August 2017

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Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human X-linked retinitis pigmentosa

23 August 2017

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Gene therapy for retinitis pigmentosa caused by MFRP mutations: human phenotype and preliminary proof of concept

23 August 2017

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Spectral domain optical coherence tomography (SD-OCT) assessment of the healthy female canine retina and optic nerve

23 August 2017

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Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years

23 August 2017

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Residual electroretinograms in young Leber congenital amaurosis patients with mutations of AIPL1

23 August 2017

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Gene therapy using self-complementary Y733F capsid mutant AAV2/8 restores vision in a model of early onset Leber congenital amaurosis

23 August 2017

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Long-term preservation of cone photoreceptors and restoration of cone function by gene therapy in the guanylate cyclase-1 knockout (GC1KO) mouse.

23 August 2017

1 reference

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Long-term retinal function and structure rescue using capsid mutant AAV8 vector in the rd10 mouse, a model of recessive retinitis pigmentosa.

23 August 2017

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Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina

23 August 2017

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Gene therapy rescues cone function in congenital achromatopsia

23 August 2017

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Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration

23 August 2017

1 reference

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AAV retinal transduction in a large animal model species: comparison of a self-complementary AAV2/5 with a single-stranded AAV2/5 vector.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Human RPE65 gene therapy for Leber congenital amaurosis: persistence of early visual improvements and safety at 1 year

23 August 2017

1 reference

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High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

23 August 2017

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Restoration of visual function in retinal degeneration mice by ectopic expression of melanopsin.

23 August 2017

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Characterization of a canine model of autosomal recessive retinitis pigmentosa due to a PDE6A mutation

23 August 2017

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Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial

23 August 2017

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Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses

23 August 2017

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Effect of gene therapy on visual function in Leber's congenital amaurosis

23 August 2017

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Safety and efficacy of gene transfer for Leber's congenital amaurosis

23 August 2017

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Measurement of retinal nerve fiber layer thickness in normal and glaucomatous Cocker Spaniels by scanning laser polarimetry

23 August 2017

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Ranibizumab for neovascular age-related macular degeneration

23 August 2017

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Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Pseudotyped AAV vectors for constitutive and regulated gene expression in the eye.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Müller cell and neuronal remodeling in retinal detachment and reattachment and their potential consequences for visual recovery: a review and reconsideration of recent data

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Experimental retinal detachment: a paradigm for understanding the effects of induced photoreceptor degeneration

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Detection of intact rAAV particles up to 6 years after successful gene transfer in the retina of dogs and primates

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Novel AAV serotypes for improved ocular gene transfer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Virally delivered channelrhodopsin-2 safely and effectively restores visual function in multiple mouse models of blindness

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Changes in adeno-associated virus-mediated gene delivery in retinal degeneration

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Ectopic expression of multiple microbial rhodopsins restores ON and OFF light responses in retinas with photoreceptor degeneration

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Direct comparison of administration routes for AAV8-mediated ocular gene therapy

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Evaluation of Italian patients with leber congenital amaurosis due to AIPL1 mutations highlights the potential applicability of gene therapy

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Improvement of visual performance with intravitreal administration of 9-cis-retinal in Rpe65-mutant dogs.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Human retinal disease from AIPL1 gene mutations: foveal cone loss with minimal macular photoreceptors and rod function remaining

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Assessment of ocular transduction using single-stranded and self-complementary recombinant adeno-associated virus serotype 2/8.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Restoration of visual response in aged dystrophic RCS rats using AAV-mediated channelopsin-2 gene transfer.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Gene expression networks underlying retinoic acid-induced differentiation of human retinoblastoma cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Kinetics of transgene expression in mouse retina following sub-retinal injection of recombinant adeno-associated virus

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Gene therapy restores vision in a canine model of childhood blindness

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Topographic variations in the rabbit and primate internal limiting membrane

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880610

Optical coherence tomography and autofluorescence findings in areas with geographic atrophy due to age-related macular degeneration.

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FGT.2013.64

cGMP phosphodiesterase-alpha mutation causes progressive retinal atrophy in the Cardigan Welsh corgi dog

21 January 2018

1 reference

12 December 2020

Structure of the human vitreoretinal border region

1 reference

12 December 2020

Apoptotic photoreceptor degeneration in experimental retinal detachment

1 reference

12 December 2020

PORES IN THE INTERNAL LIMITING MEMBRANE OF THE HUMAN RETINA

1 reference

12 December 2020

Identifiers

DOI

10.1038/GT.2013.64

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24225638%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24225638%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

24225638

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24225638%20AND%20SRC:MED&resulttype=core&format=json