Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses (Q36685842)

15 August 2017

Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses (English)

1 reference

15 August 2017

0 references

Adeno-associated virus

object named as

adeno-associated virus 2

1 reference

based on heuristic

inferred from title

author

Mavis Agbandje-McKenna

object named as

Mavis Agbandje-McKenna

1 reference

15 August 2017

Li Zhong

1 reference

15 August 2017

Baozheng Li

1 reference

15 August 2017

Cathryn S Mah

1 reference

15 August 2017

Lakshmanan Govindasamy

1 reference

15 August 2017

Mario Cooper

1 reference

15 August 2017

Roland W Herzog

1 reference

15 August 2017

Irene Zolotukhin

1 reference

15 August 2017

Kenneth H Warrington

1 reference

15 August 2017

Kirsten A Weigel-Van Aken

1 reference

15 August 2017

Jacqueline A Hobbs

1 reference

15 August 2017

Sergei Zolotukhin

1 reference

15 August 2017

Nicholas Muzyczka

1 reference

15 August 2017

Arun Srivastava

1 reference

15 August 2017

language of work or name

English

0 references

publication date

29 May 2008

1 reference

Proceedings of the National Academy of Sciences of the United States of America

15 August 2017

1 reference

15 August 2017

105

1 reference

15 August 2017

1 reference

15 August 2017

7827-7832

1 reference

describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2402387/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Self-complementary adeno-associated virus 2 (AAV)-T cell protein tyrosine phosphatase vectors as helper viruses to improve transduction efficiency of conventional single-stranded AAV vectors in vitro and in vivo

30 September 2017

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Rapid uncoating of vector genomes is the key to efficient liver transduction with pseudotyped adeno-associated virus vectors

30 September 2017

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Distinct classes of proteasome-modulating agents cooperatively augment recombinant adeno-associated virus type 2 and type 5-mediated transduction from the apical surfaces of human airway epithelia

30 September 2017

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Heat-shock treatment-mediated increase in transduction by recombinant adeno-associated virus 2 vectors is independent of the cellular heat-shock protein 90

30 September 2017

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Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer

30 September 2017

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Cell-type-specific characteristics modulate the transduction efficiency of adeno-associated virus type 2 and restrain infection of endothelial cells

30 September 2017

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30 September 2017

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The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy.

30 September 2017

1 reference

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Ubiquitination of both adeno-associated virus type 2 and 5 capsid proteins affects the transduction efficiency of recombinant vectors.

30 September 2017

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30 September 2017

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Adeno-associated virus type 2-mediated gene transfer: altered endocytic processing enhances transduction efficiency in murine fibroblasts

30 September 2017

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30 September 2017

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30 September 2017

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Endocytosis and nuclear trafficking of adeno-associated virus type 2 are controlled by rac1 and phosphatidylinositol-3 kinase activation

30 September 2017

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30 September 2017

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Impaired intracellular trafficking of adeno-associated virus type 2 vectors limits efficient transduction of murine fibroblasts

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector

30 September 2017

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30 September 2017

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A phase I study of an adeno-associated virus-CFTR gene vector in adult CF patients with mild lung disease

30 September 2017

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Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors

30 September 2017

1 reference

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Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis

30 September 2017

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Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector

30 September 2017

1 reference

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Improved methods for building protein models in electron density maps and the location of errors in these models

30 September 2017

1 reference

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Use of Adeno-Associated Virus as a General Transduction Vector for Mammalian Cells

30 September 2017

1 reference

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Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector.

30 September 2017

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Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

28 June 2018

1 reference

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A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2402387

CD8(+) T-cell responses to adeno-associated virus capsid in humans

5 September 2018

1 reference

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Evaluation of primitive murine hematopoietic stem and progenitor cell transduction in vitro and in vivo by recombinant adeno-associated virus vector serotypes 1 through 5.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2402387

rAAV2 traffics through both the late and the recycling endosomes in a dose-dependent fashion

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2402387

Improved transduction of primary murine hepatocytes by recombinant adeno-associated virus 2 vectors in vivo

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2402387

Phase I trial of intramuscular injection of a recombinant adeno-associated virus alpha 1-antitrypsin (rAAV2-CB-hAAT) gene vector to AAT-deficient adults

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2402387

Isoflurane activates PKC and Ca(2+) -calmodulin-dependent protein kinase II via MAP kinase signaling in cultured vascular smooth muscle cells

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2402387

Adeno-associated virus 2-mediated transduction and erythroid lineage-restricted long-term expression of the human beta-globin gene in hematopoietic cells from homozygous beta-thalassemic mice

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2402387

Two-stage PCR protocol allowing introduction of multiple mutations, deletions and insertions using QuikChange Site-Directed Mutagenesis

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18511559

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0802866105

1 reference

15 August 2017

0 references

1 reference

15 August 2017

PubMed publication ID

18511559

1 reference