Large-scale remodeling of a repressed exon ribonucleoprotein to an exon definition complex active for splicing. (Q37437764)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27882870%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

title

Large-scale remodeling of a repressed exon ribonucleoprotein to an exon definition complex active for splicing (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27882870%20AND%20SRC:MED&resulttype=core&format=json

ribonucleoprotein complex

28 March 2020

main subject

1 reference

inferred from title

author

Somsakul Pop Wongpalee

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28 March 2020

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28 March 2020

James A Wohlschlegel

1 reference

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28 March 2020

Ajay Vashisht

1 reference

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28 March 2020

Shalini Sharma

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28 March 2020

Darryl Chui

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28 March 2020

language of work or name

English

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publication date

24 November 2016

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28 March 2020

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28 March 2020

volume

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The splicing regulator PTBP1 controls the activity of the transcription factor Pbx1 during neuronal differentiation.

28 March 2020

cites work

1 reference

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3

23 August 2017

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Direct competition between hnRNP C and U2AF65 protects the transcriptome from the exonization of Alu elements

23 August 2017

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23 August 2017

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Exon and intron definition in pre-mRNA splicing

23 August 2017

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Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness

23 August 2017

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Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2.

23 August 2017

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Structure, function and regulation of spliceosomal RNA helicases

23 August 2017

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Dynamic protein-protein interaction wiring of the human spliceosome

23 August 2017

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PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2.

23 August 2017

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Crystallographic Analysis of Polypyrimidine Tract-Binding Protein-Raver1 Interactions Involved in Regulation of Alternative Splicing

23 August 2017

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Evolution of SR protein and hnRNP splicing regulatory factors

23 August 2017

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From unwinding to clamping - the DEAD box RNA helicase family

23 August 2017

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Spliceosome Structure and Function

23 August 2017

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U1 snRNA Directly Interacts with Polypyrimidine Tract-Binding Protein during Splicing Repression

23 August 2017

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RNA helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5' splice site

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping

23 August 2017

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23 August 2017

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The CUGBP2 splicing factor regulates an ensemble of branchpoints from perimeter binding sites with implications for autoregulation

23 August 2017

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23 August 2017

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The SR protein family of splicing factors: master regulators of gene expression

23 August 2017

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23 August 2017

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P68 RNA helicase (DDX5) alters activity of cis- and trans-acting factors of the alternative splicing of H-Ras

23 August 2017

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L30 binds the nascent RPL30 transcript to repress U2 snRNP recruitment

23 August 2017

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23 August 2017

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23 August 2017

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MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development

23 August 2017

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23 August 2017

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The polypyrimidine tract binding protein (PTB) represses splicing of exon 6B from the beta-tropomyosin pre-mRNA by directly interfering with the binding of the U2AF65 subunit

23 August 2017

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23 August 2017

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Regulation of Fas alternative splicing by antagonistic effects of TIA-1 and PTB on exon definition

23 August 2017

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ATPase/helicase activities of p68 RNA helicase are required for pre-mRNA splicing but not for assembly of the spliceosome

23 August 2017

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23 August 2017

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Regulation of alternative splicing by PTB and associated factors.

23 August 2017

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Exon repression by polypyrimidine tract binding protein

23 August 2017

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23 August 2017

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The PTB interacting protein raver1 regulates alpha-tropomyosin alternative splicing

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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p68 RNA helicase is an essential human splicing factor that acts at the U1 snRNA-5' splice site duplex

23 August 2017

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Messenger-RNA-binding proteins and the messages they carry

23 August 2017

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Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

23 August 2017

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A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.

23 August 2017

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Polypyrimidine tract binding protein antagonizes exon definition

23 August 2017

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The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing

23 August 2017

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Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein

23 August 2017

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Multisite RNA binding and release of polypyrimidine tract binding protein during the regulation of c-src neural-specific splicing

23 August 2017

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Functional association of U2 snRNP with the ATP-independent spliceosomal complex E

23 August 2017

1 reference

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Evidence for a linear search in bimolecular 3' splice site AG selection

23 August 2017

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Resolution of the mammalian E complex and the ATP-dependent spliceosomal complexes on native agarose mini-gels

23 August 2017

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hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells

23 August 2017

1 reference

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A neuron-specific splicing switch mediated by an array of pre-mRNA repressor sites: evidence of a regulatory role for the polypyrimidine tract binding protein and a brain-specific PTB counterpart

23 August 2017

1 reference

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The Polypyrimidine Tract Binding Protein Binds Upstream of Neural Cell-Specific c-src Exon N1 To Repress the Splicing of the Intron Downstream

23 August 2017

1 reference

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Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A

23 August 2017

1 reference

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hnRNP proteins and the biogenesis of mRNA

23 August 2017

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Specific interactions between proteins implicated in splice site selection and regulated alternative splicing

23 August 2017

1 reference

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Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

23 August 2017

1 reference

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SR proteins promote the first specific recognition of Pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex

23 August 2017

1 reference

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Exon recognition in vertebrate splicing

23 August 2017

1 reference

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Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins

23 August 2017

1 reference

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Conserved intron elements repress splicing of a neuron-specific c-src exon in vitro

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes

23 August 2017

1 reference

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The essential pre-mRNA splicing factor SF2 influences 5' splice site selection by activating proximal sites.

23 August 2017

1 reference

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Protein composition of mammalian spliceosomes assembled in vitro

23 August 2017

1 reference

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Exon definition may facilitate splice site selection in RNAs with multiple exons

23 August 2017

1 reference

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A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription

23 August 2017

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Knocking down the expression of TRA2β inhibits the proliferation and migration of human glioma cells

23 August 2017

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RAVER1 is a coactivator of MDA5-mediated cellular antiviral response.

6 September 2017

1 reference

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Polypyrimidine tract binding protein blocks the 5' splice site-dependent assembly of U2AF and the prespliceosomal E complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Roles for SR proteins and hnRNP A1 in the regulation of c-src exon N1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Polypyrimidine tract binding protein controls the transition from exon definition to an intron defined spliceosome

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

U1 snRNP-ASF/SF2 interaction and 5' splice site recognition: characterization of required elements.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Does steric interference between splice sites block the splicing of a short c-src neuron-specific exon in non-neuronal cells?

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Quaking and PTB control overlapping splicing regulatory networks during muscle cell differentiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

The generally expressed hnRNP F is involved in a neural-specific pre-mRNA splicing event

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Trans splicing of mRNA precursors

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Preparation of extracts from higher eukaryotes

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

An ATP-independent complex commits pre-mRNA to the mammalian spliceosome assembly pathway

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

The primer extension assay.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Optimized fast and sensitive acquisition methods for shotgun proteomics on a quadrupole orbitrap mass spectrometer

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Exon definition complexes contain the tri-snRNP and can be directly converted into B-like precatalytic splicing complexes

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Census for proteome quantification

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

HnRNP L-mediated regulation of mammalian alternative splicing by interference with splice site recognition

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Novel modes of splicing repression by PTB.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Identification of ubiquitination sites and determination of ubiquitin-chain architectures by mass spectrometry

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Antagonistic regulation of alpha-actinin alternative splicing by CELF proteins and polypyrimidine tract binding protein

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Early organization of pre-mRNA during spliceosome assembly.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3' splice site AG.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

The evolutionary landscape of alternative splicing in vertebrate species

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5122456

A two-step mechanism for 5' and 3' splice-site pairing

2 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.7554%2FELIFE.19743

A functional association between the 5' and 3' splice site is established in the earliest prespliceosome complex (E) in mammals

21 January 2018

1 reference

12 December 2020

U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing

1 reference

12 December 2020

An exonic splicing silencer represses spliceosome assembly after ATP-dependent exon recognition

1 reference

12 December 2020

Activation of c-src neuron-specific splicing by an unusual RNA element in vivo and in vitro

1 reference

12 December 2020

U1 snRNP targets an essential splicing factor, U2AF65, to the 3' splice site by a network of interactions spanning the exon

1 reference

12 December 2020

Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing

1 reference

12 December 2020

Identifiers

DOI

10.7554/ELIFE.19743

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27882870%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27882870%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

PubMed publication ID

27882870

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27882870%20AND%20SRC:MED&resulttype=core&format=json