The Synergistic Effect of Conditional Pten Loss and Oncogenic K-ras Mutation on Endometrial Cancer Development Occurs via Decreased Progesterone Receptor Action (Q37400307)

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scientific article published on 27 October 2009

Language	Label	Description	Also known as
English	The Synergistic Effect of Conditional Pten Loss and Oncogenic K-ras Mutation on Endometrial Cancer Development Occurs via Decreased Progesterone Receptor Action	scientific article published on 27 October 2009

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

The Synergistic Effect of Conditional Pten Loss and Oncogenic K-ras Mutation on Endometrial Cancer Development Occurs via Decreased Progesterone Receptor Action (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

endometrial cancer

1 reference

based on heuristic

inferred from title

6

object named as

John P Lydon

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

author name string

Tae Hoon Kim

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Jinrong Wang

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Kevin Y Lee

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Heather L Franco

4

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Russell R Broaddus

5

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Jae-Wook Jeong

7

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Francesco J Demayo

8

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

publication date

27 October 2009

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Journal of oncology

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

2010

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

139087

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

copyright license

Creative Commons Attribution 3.0 Unported

1 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

1 reference

April 2022 Public Data File from Crossref

Conditional loss of uterine Pten unfailingly and rapidly induces endometrial cancer in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Pathogenesis of ovarian cancer: lessons from morphology and molecular biology and their clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Cancer statistics, 2008

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

PI3K/PTEN signaling in tumorigenesis and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Biological roles of estrogen and progesterone in human endometrial carcinoma--new developments in potential endocrine therapy for endometrial cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Molecular and pathologic aspects of endometrial carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Upregulation of TCF4 expression as a transcriptional target of beta-catenin/p300 complexes during trans-differentiation of endometrial carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Cre-mediated recombination in cell lineages that express the progesterone receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Progesterone receptor by immunohistochemistry and clinical outcome in breast cancer: a validation study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Hormonal interactions in endometrial cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

PTEN mutations and microsatellite instability in complex atypical hyperplasia, a precursor lesion to uterine endometrioid carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Pten is essential for embryonic development and tumour suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Mutation of the PTEN tumor suppressor gene in endometrial hyperplasias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Estrogens, progesterone, and endometrial cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Blastocyst's state of activity determines the "window" of implantation in the receptive mouse uterus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Increased Risk of Endometrial Carcinoma among Users of Conjugated Estrogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

6 September 2017

Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

14 September 2017

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

28 September 2017

Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

26 June 2018

Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

26 June 2018

Paracrine regulation of epithelial progesterone receptor and lactoferrin by progesterone in the mouse uterus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

26 June 2018

Prognostic significance of progesterone receptor immunohistochemistry in endometrial carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

26 June 2018

Gene expression analysis reveals a signature of estrogen receptor activation upon loss of Pten in a mouse model of endometrial cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

2 September 2018

Akt-mediated phosphorylation and activation of estrogen receptor alpha is required for endometrial neoplastic transformation in Pten+/- mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

2 September 2018

Progesterone inhibits the estrogen-induced phosphoinositide 3-kinase-->AKT-->GSK-3beta-->cyclin D1-->pRB pathway to block uterine epithelial cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

2 September 2018

Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

2 September 2018

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

2 September 2018

ERbeta has nongenomic action in caveolae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

2 September 2018

Relative expression of progesterone receptors A and B in endometrioid cancers of the endometrium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768008

2 September 2018

Paracrine regulation of epithelial progesterone receptor by estradiol in the mouse female reproductive tract

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F139087

21 January 2018

Endometrial Carcinoma

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F139087

21 January 2018

The clinicopathological significance of K-RAS point mutation and gene amplification in endometrial cancer

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F139087

21 January 2018

Combined Estrogen and Progesterone Use and Endometrial Cancer

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F139087

21 January 2018

Hypertrophy and hyperplasia in the mouse uterus after oestrogen treatment: an autoradiographic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19884980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational Analysis of thePTENGene in Endometrial Carcinoma and Hyperplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19884980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen and progesterone receptors in endometrial cancer and their prognostic relevance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19884980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell type-specific localization of c-myc protein in the mouse uterus: modulation by steroid hormones and analysis of the periimplantation period

1 reference

https://pubmed.ncbi.nlm.nih.gov/19884980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibition by progesterone of uterine epithelial proliferation in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/19884980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-catenin mutation in carcinoma of the uterine endometrium

1 reference

https://pubmed.ncbi.nlm.nih.gov/19884980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endometrial carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19884980

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1155/2010/139087

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

ResearchGate publication ID

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