Asiatic acid isolated from Centella asiatica inhibits TGF-β1-induced collagen expression in human keloid fibroblasts via PPAR-γ activation (Q37317161)

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scientific article published on 25 October 2013

Language	Label	Description	Also known as
English	Asiatic acid isolated from Centella asiatica inhibits TGF-β1-induced collagen expression in human keloid fibroblasts via PPAR-γ activation	scientific article published on 25 October 2013

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Asiatic acid isolated from Centella asiatica inhibits TGF-β1-induced collagen expression in human keloid fibroblasts via PPAR-γ activation (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Centella asiatica

object named as

Centella asiatica

1 reference

based on heuristic

inferred from title

author name string

Difei Bian

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Jizhou Zhang

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Xin Wu

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Yannong Dou

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Yan Yang

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Qian Tan

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Yufeng Xia

7

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Zhunan Gong

8

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Yue Dai

9

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

language of work or name

0 references

publication date

25 October 2013

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

International Journal of Biological Sciences

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Europe PubMed Central

PMC publication ID

19 August 2017

9

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

10

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

1032-1042

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Identification of Major Active Ingredients Responsible for Burn Wound Healing of Centella asiatica Herbs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

Thiazolidinediones and PPARγ agonists: time for a reassessment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

Asiatic acid inhibits liver fibrosis by blocking TGF-beta/Smad signaling in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

Advances in the treatment of keloids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

PAI-1 in tissue fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

Oxygen in acute and chronic wound healing

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9 September 2017

Macrophages, inflammation, and insulin resistance

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9 September 2017

Molecular dissection of abnormal wound healing processes resulting in keloid disease.

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9 September 2017

Keloids: current concepts of pathogenesis (review).

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9 September 2017

Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts.

1 reference

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9 September 2017

Hypertrophic scars and keloids--a review of their pathophysiology, risk factors, and therapeutic management.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

Potential cellular and molecular causes of hypertrophic scar formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

Adenoviral overexpression and small interfering RNA suppression demonstrate that plasminogen activator inhibitor-1 produces elevated collagen accumulation in normal and keloid fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

A Novel Mechanism of PPARgamma Regulation of TGFbeta1: Implication in Cancer Biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

The Role of PPARs in Cancer

1 reference

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9 September 2017

Wound repair and regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonists attenuate the profibrotic response induced by TGF-beta1 in renal interstitial fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

Cellular and molecular mechanisms of fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

PPARs: therapeutic targets for metabolic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

TGF-beta signaling and the fibrotic response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

The mechanisms of action of PPARs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

9 September 2017

PPARgamma agonists prevent TGFbeta1/Smad3-signaling in human hepatic stellate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

14 September 2017

Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

14 September 2017

Asiaticoside suppresses collagen expression and TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

26 June 2018

Suppression of transforming growth factor beta/smad signaling in keloid-derived fibroblasts by quercetin: implications for the treatment of excessive scars.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

26 June 2018

Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

26 June 2018

FK506 inhibits the enhancing effects of transforming growth factor (TGF)-β1 on collagen expression and TGF-β/Smad signalling in keloid fibroblasts: implication for new therapeutic approach.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

2 September 2018

Compound Astragalus and Salvia miltiorrhiza extract inhibits cell proliferation, invasion and collagen synthesis in keloid fibroblasts by mediating transforming growth factor-β / Smad pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

2 September 2018

Mechanisms of transforming growth factor beta(1)/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

2 September 2018

Troglitazone suppresses transforming growth factor-beta1-induced collagen type I expression in keloid fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

2 September 2018

Decreased expression of inhibitory SMAD6 and SMAD7 in keloid scarring.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

2 September 2018

Keloid-derived fibroblasts show increased secretion of factors involved in collagen turnover and depend on matrix metalloproteinase for migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

2 September 2018

Asiatic acid induces apoptosis in SK-MEL-2 human melanoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831116

2 September 2018

Asiatic acid, a triterpene, induces apoptosis through intracellular Ca2+ release and enhanced expression of p53 in HepG2 human hepatoma cells

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2 September 2018

New innovations in scar management

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https://pubmed.ncbi.nlm.nih.gov/24250248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of transforming growth factor beta 1, 2, and 3 proteins in keloids

1 reference

https://pubmed.ncbi.nlm.nih.gov/24250248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pirfenidone: significant treatment effects in idiopathic pulmonary fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24250248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.7150/IJBS.7273

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

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