Compound Astragalus and Salvia miltiorrhiza extract inhibits cell proliferation, invasion and collagen synthesis in keloid fibroblasts by mediating transforming growth factor-β / Smad pathway. (Q54345480)

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English	Compound Astragalus and Salvia miltiorrhiza extract inhibits cell proliferation, invasion and collagen synthesis in keloid fibroblasts by mediating transforming growth factor-β / Smad pathway.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

Compound Astragalus and Salvia miltiorrhiza extract inhibits cell proliferation, invasion and collagen synthesis in keloid fibroblasts by mediating transforming growth factor-β / Smad pathway. (English)

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

Salvia miltiorrhiza

object named as

Salvia miltiorrhiza

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based on heuristic

inferred from title

3

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

author name string

S He

1

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

Y Yang

2

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

W Huang

4

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

X Zhang

5

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

S Yang

6

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

X Zhang

7

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

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publication date

5 December 2011

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

British Journal of Dermatology

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PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

166

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

3

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

564-574

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

Hypertrophic scars and keloids: etiology and management

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Keloids: current concepts of pathogenesis (review).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Keloids: Pathogenesis, Clinical Features, and Management

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

The effect of TGF-beta on keloid fibroblast proliferation and collagen synthesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Differential expression of transforming growth factor-beta receptors I and II and activation of Smad 3 in keloid fibroblasts

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Smad3 signalling plays an important role in keloid pathogenesis via epithelial-mesenchymal interactions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Modulation of collagen synthesis in keloid fibroblasts by silencing Smad2 with siRNA.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Inhibition of Smad3 expression decreases collagen synthesis in keloid disease fibroblasts

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Decreased expression of inhibitory SMAD6 and SMAD7 in keloid scarring.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Compound Astragalus and Salvia miltiorrhiza Extract exerts anti-fibrosis by mediating TGF-beta/Smad signaling in myofibroblasts

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Transforming growth factor beta (TGFbeta) and keloid disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Keloid-derived fibroblasts have a diminished capacity to produce prostaglandin E2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Recombinant human decorin inhibits cell proliferation and downregulates TGF-beta1 production in hypertrophic scar fibroblasts

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Mechanisms of transforming growth factor beta(1)/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Asiaticoside suppresses collagen expression and TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Suppression of TGF-β1/SMAD pathway and extracellular matrix production in primary keloid fibroblasts by curcuminoids: its potential therapeutic use in the chemoprevention of keloid.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Green tea polyphenol epigallocatechin-3-gallate suppresses collagen production and proliferation in keloid fibroblasts via inhibition of the STAT3-signaling pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Keloid-derived fibroblasts show increased secretion of factors involved in collagen turnover and depend on matrix metalloproteinase for migration

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Keloid fibroblasts exhibit an altered response to TGF-beta

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Overexpression of insulin-like growth factor-1 (IGF-I) receptor and the invasiveness of cultured keloid fibroblasts

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

TGFbeta in Cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Modulation of TGF-beta signaling during progression of chronic liver diseases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Smad transcription factors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Reversible Smad-dependent signaling between tumor suppression and oncogenesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Transforming growth factor-beta during carcinogenesis: the shift from epithelial to mesenchymal signaling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Increased Plasminogen Activator Inhibitor-1 in Keloid Fibroblasts May Account for their Elevated Collagen Accumulation in Fibrin Gel Cultures

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Elevated levels of plasminogen activator inhibitor-1 may account for the altered fibrinolysis by keloid fibroblasts.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Mechanisms of hypoxic regulation of plasminogen activator inhibitor-1 gene expression in keloid fibroblasts

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2011.10674.X

21 January 2018

Identifiers

10.1111/J.1365-2133.2011.10674.X

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21967214

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