The proline-rich domain in p63 is necessary for the transcriptional and apoptosis-inducing activities of TAp63 (Q37142886)

18 August 2017

The proline-rich domain in p63 is necessary for the transcriptional and apoptosis-inducing activities of TAp63 (English)

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18 August 2017

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E S Helton

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18 August 2017

J Zhang

series ordinal

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18 August 2017

X Chen

series ordinal

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18 August 2017

language of work or name

English

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publication date

26 November 2007

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18 August 2017

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18 August 2017

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18 August 2017

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18 August 2017

2843-2850

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Probing p53 biological functions through the use of genetically engineered mouse models

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

The proline-rich region of mouse p53 influences transactivation and apoptosis but is largely dispensable for these functions.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

deltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

P63 gene mutations and human developmental syndromes.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

p63 is a p53 homologue required for limb and epidermal morphogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

High-efficiency transformation of mammalian cells by plasmid DNA

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

The codon 72 polymorphism-specific effects of human p53 are absent in mouse cells: implications on generation of mouse models

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

The unique NH2-terminally deleted (DeltaN) residues, the PXXP motif, and the PPXY motif are required for the transcriptional activity of the DeltaN variant of p63.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662334

Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210948

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210948

The C terminus of p53 family proteins is a cell fate determinant

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210948

p63 and p73 are not required for the development and p53-dependent apoptosis of T cells

21 January 2018

1 reference

12 December 2020

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

1 reference

12 December 2020

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

1 reference

12 December 2020

Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity

1 reference

12 December 2020

Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.ONC.1210948

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18 August 2017

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18 August 2017

PubMed publication ID

18037962

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