Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains (Q24321258)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446784%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

title

Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains (English)

1 reference

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15 December 2019

0 references

1 reference

GOA release 2020-03-11

positive regulation of transcription, DNA-templated

1 reference

GOA release 2020-03-11

1 reference

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15 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446784%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Pamela Ghioni

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446784%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Fabrizio Bolognese

series ordinal

1 reference

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15 December 2019

Roberto Mantovani

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446784%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Luisa Guerrini

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446784%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

language of work or name

English

0 references

publication date

1 December 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446784%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

15 December 2019

published in

1 reference

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15 December 2019

volume

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15 December 2019

issue

1 reference

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15 December 2019

page(s)

8659-8668

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446784%20AND%20SRC:MED&resulttype=core&format=json

Physical interaction with Yes-associated protein enhances p73 transcriptional activity

15 December 2019

cites work

1 reference

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p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Cloning and functional analysis of human p51, which structurally and functionally resembles p53

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Different members of the Sp1 multigene family exert opposite transcriptional regulation of the long terminal repeat of HIV-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Solution structure of a conserved C-terminal domain of p73 with structural homology to the SAM domain.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

19 March 2017

1 reference

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p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Identification and tissue distribution of novel KET/p63 splice variants

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Orchestrated response: a symphony of transcription factors for gene control

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

p63 is a p53 homologue required for limb and epidermal morphogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers

7 April 2017

1 reference

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The p53 and Mdm2 families in cancer.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

The human MDM2 oncoprotein increases the transcriptional activity and the protein level of the p53 homolog p63.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

p53 family update: p73 and p63 develop their own identities

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

P63 and P73: P53 mimics, menaces and more

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

p63 identifies keratinocyte stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

The tumour suppressor protein p53 can repress transcription of cyclin B.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Lack of homozygously inactivated p73 in single-copy MYCN primary neuroblastomas and neuroblastoma cell lines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

p63 and p73 transactivate differentiation gene promoters in human keratinocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Split-hand/split-foot malformation is caused by mutations in the p63 gene on 3q27.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

p63 and p73: old members of a new family

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

The p53/p63/p73 family of transcription factors: overlapping and distinct functions.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Regulation and function of the p53-related proteins: same family, different rules

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Twenty years of p53 research: structural and functional aspects of the p53 protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Deletion of the COOH-terminal region of p73alpha enhances both its transactivation function and DNA-binding activity but inhibits induction of apoptosis in mammalian cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

A functional p53-responsive intronic promoter is contained within the humanmdm2gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Role of chromatin and Xenopus laevis heat shock transcription factor in regulation of transcription from the X. laevis hsp70 promoter in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Wild-type p53 can down-modulate the activity of various promoters

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Analysis of p53 mutants for transcriptional activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

p53 Homologue p63 represses epidermal growth factor receptor expression.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

p63 Gene mutations in eec syndrome, limb-mammary syndrome, and isolated split hand-split foot malformation suggest a genotype-phenotype correlation.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

p53 Family members p63 and p73 are SAM domain-containing proteins

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Predicting functions from protein sequences--where are the bottlenecks?

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

p53 tumor-suppressor gene: Clues to molecular carcinogenesis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Sp3 is a bifunctional transcription regulator with modular independent activation and repression domains.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139859

Regulation of the human hsp70 promoter by p53

29 November 2018

1 reference

12 December 2020

Differential DNA sequence specificity and regulation of HIV-1 enhancer activity by cRel-RelA transcription factor

1 reference

12 December 2020

NF-Y binding to twin CCAAT boxes: role of Q-rich domains and histone fold helices

1 reference

12 December 2020

Identification of a transactivation activity in the COOH-terminal region of p73 which is impaired in the naturally occurring mutants found in human neuroblastomas

1 reference

12 December 2020

Promoter specificity and stability control of the p53-related protein p73

1 reference

12 December 2020

New p73 variants with altered C-terminal structures have varied transcriptional activities

1 reference

12 December 2020

p51A (TAp63gamma), a p53 homolog, accumulates in response to DNA damage for cell regulation

1 reference

12 December 2020

Checkpoints: How to activate p53

1 reference

Crossref

https://api.crossref.org/works/10.1128%2FMCB.22.24.8659-8668.2002

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1128/MCB.22.24.8659-8668.2002

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446784%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446784%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

PubMed publication ID

12446784

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446784%20AND%20SRC:MED&resulttype=core&format=json