NLRs at the intersection of cell death and immunity (Q37117573)

18 August 2017

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title

NLRs at the intersection of cell death and immunity (English)

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18 August 2017

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Jenny P-Y Ting

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18 August 2017

Stephen B Willingham

series ordinal

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18 August 2017

Daniel T Bergstralh

series ordinal

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18 August 2017

publication date

1 May 2008

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Nature Reviews Immunology

18 August 2017

published in

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18 August 2017

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18 August 2017

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18 August 2017

page(s)

372-379

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IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients

18 August 2017

cites work

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Genomic insights into the immune system of the sea urchin

21 January 2018

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Plant disease resistance protein signaling: NBS-LRR proteins and their partners

31 March 2020

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Programmed cell death, mitochondria and the plant hypersensitive response

31 March 2020

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

31 March 2020

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The apoptosome: signalling platform of cell death

31 March 2020

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The machinery of programmed cell death.

31 March 2020

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Caspase structure, proteolytic substrates, and function during apoptotic cell death

31 March 2020

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Necrotic death as a cell fate

31 March 2020

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Death by design: apoptosis, necrosis and autophagy

31 March 2020

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Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

31 March 2020

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High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

31 March 2020

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Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

31 March 2020

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The role of high mobility group box-1 protein in severe sepsis

31 March 2020

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Salmonella induces macrophage death by caspase-1-dependent necrosis

31 March 2020

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Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells

31 March 2020

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The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

31 March 2020

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Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC.

31 March 2020

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The PYRIN-CARD protein ASC is an activating adaptor for caspase-1

31 March 2020

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The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

31 March 2020

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NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

31 March 2020

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Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling

31 March 2020

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Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

31 March 2020

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Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

31 March 2020

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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

31 March 2020

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Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

31 March 2020

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Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

31 March 2020

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Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

31 March 2020

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Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

31 March 2020

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Cryopyrin activates the inflammasome in response to toxins and ATP

31 March 2020

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Gout-associated uric acid crystals activate the NALP3 inflammasome

31 March 2020

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Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

31 March 2020

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Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation

31 March 2020

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Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

31 March 2020

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The apoptosome: physiological, developmental, and pathological modes of regulation

31 March 2020

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Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

31 March 2020

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Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila.

31 March 2020

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Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

31 March 2020

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Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity

31 March 2020

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The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection

31 March 2020

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Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages

31 March 2020

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Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1

31 March 2020

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Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

31 March 2020

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RIG-I family RNA helicases: cytoplasmic sensor for antiviral innate immunity

31 March 2020

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NLRX1 is a regulator of mitochondrial antiviral immunity

31 March 2020

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Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

31 March 2020

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Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis

31 March 2020

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De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases

31 March 2020

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Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes

31 March 2020

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CATERPILLERs, pyrin and hereditary immunological disorders

31 March 2020

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Enhanced interleukin-1beta and interleukin-18 release in a patient with chronic infantile neurologic, cutaneous, articular syndrome

31 March 2020

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Disease-associated CIAS1 mutations induce monocyte death, revealing low-level mosaicism in mutation-negative cryopyrin-associated periodic syndrome patients

31 March 2020

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Pathogen-induced apoptosis of macrophages: a common end for different pathogenic strategies

31 March 2020

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Virulent Shigella flexneri causes damage to mitochondria and triggers necrosis in infected human monocyte-derived macrophages

31 March 2020

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A novel caspase-1/toll-like receptor 4-independent pathway of cell death induced by cytosolic Shigella in infected macrophages

31 March 2020

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Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death

31 March 2020

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Critical role for cathepsin B in mediating caspase-1-dependent interleukin-18 maturation and caspase-1-independent necrosis triggered by the microbial toxin nigericin

31 March 2020

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Maitotoxin induces calpain but not caspase-3 activation and necrotic cell death in primary septo-hippocampal cultures

31 March 2020

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Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages

31 March 2020

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Disease-associated mutations in CIAS1 induce cathepsin B-dependent rapid cell death of human THP-1 monocytic cells

31 March 2020

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI2296

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Dimensions Publication ID

18 August 2017

1007607511

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