NLRs at the intersection of cell death and immunity (Q37117573)

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scientific article published on May 2008

Language	Label	Description	Also known as
English	NLRs at the intersection of cell death and immunity	scientific article published on May 2008

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 August 2017

1 reference

Europe PubMed Central

NLRs at the intersection of cell death and immunity (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 August 2017

1 reference

based on heuristic

inferred from title

author name string

Jenny P-Y Ting

1

1 reference

Europe PubMed Central

PubMed publication ID

18 August 2017

Stephen B Willingham

2

1 reference

Europe PubMed Central

PubMed publication ID

18 August 2017

Daniel T Bergstralh

3

1 reference

Europe PubMed Central

PubMed publication ID

18 August 2017

publication date

1 May 2008

1 reference

Europe PubMed Central

PubMed publication ID

18 August 2017

Nature Reviews Immunology

1 reference

Europe PubMed Central

PubMed publication ID

18 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

18 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

18 August 2017

372-379

1 reference

Europe PubMed Central

PubMed publication ID

18 August 2017

IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients

1 reference

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21 January 2018

Genomic insights into the immune system of the sea urchin

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31 March 2020

Plant disease resistance protein signaling: NBS-LRR proteins and their partners

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31 March 2020

Programmed cell death, mitochondria and the plant hypersensitive response

1 reference

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31 March 2020

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

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31 March 2020

The apoptosome: signalling platform of cell death

1 reference

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The machinery of programmed cell death.

1 reference

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Caspase structure, proteolytic substrates, and function during apoptotic cell death

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31 March 2020

Necrotic death as a cell fate

1 reference

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31 March 2020

Death by design: apoptosis, necrosis and autophagy

1 reference

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31 March 2020

Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

1 reference

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31 March 2020

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

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Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

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The role of high mobility group box-1 protein in severe sepsis

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Salmonella induces macrophage death by caspase-1-dependent necrosis

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Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells

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The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

1 reference

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Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC.

1 reference

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The PYRIN-CARD protein ASC is an activating adaptor for caspase-1

1 reference

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The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

1 reference

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NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

1 reference

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Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling

1 reference

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Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

1 reference

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Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

1 reference

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31 March 2020

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

1 reference

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31 March 2020

Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

1 reference

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31 March 2020

Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

1 reference

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Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

1 reference

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31 March 2020

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

1 reference

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31 March 2020

Cryopyrin activates the inflammasome in response to toxins and ATP

1 reference

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31 March 2020

Gout-associated uric acid crystals activate the NALP3 inflammasome

1 reference

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31 March 2020

Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

1 reference

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31 March 2020

Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation

1 reference

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31 March 2020

Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

1 reference

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31 March 2020

The apoptosome: physiological, developmental, and pathological modes of regulation

1 reference

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Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

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31 March 2020

Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila.

1 reference

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31 March 2020

Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

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Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity

1 reference

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31 March 2020

The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection

1 reference

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31 March 2020

Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages

1 reference

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31 March 2020

Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1

1 reference

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Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

1 reference

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RIG-I family RNA helicases: cytoplasmic sensor for antiviral innate immunity

1 reference

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31 March 2020

NLRX1 is a regulator of mitochondrial antiviral immunity

1 reference

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31 March 2020

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

1 reference

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31 March 2020

Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis

1 reference

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De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases

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Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes

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CATERPILLERs, pyrin and hereditary immunological disorders

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Enhanced interleukin-1beta and interleukin-18 release in a patient with chronic infantile neurologic, cutaneous, articular syndrome

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Disease-associated CIAS1 mutations induce monocyte death, revealing low-level mosaicism in mutation-negative cryopyrin-associated periodic syndrome patients

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Pathogen-induced apoptosis of macrophages: a common end for different pathogenic strategies

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Virulent Shigella flexneri causes damage to mitochondria and triggers necrosis in infected human monocyte-derived macrophages

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A novel caspase-1/toll-like receptor 4-independent pathway of cell death induced by cytosolic Shigella in infected macrophages

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Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death

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Critical role for cathepsin B in mediating caspase-1-dependent interleukin-18 maturation and caspase-1-independent necrosis triggered by the microbial toxin nigericin

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Maitotoxin induces calpain but not caspase-3 activation and necrotic cell death in primary septo-hippocampal cultures

1 reference

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Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages

1 reference

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Disease-associated mutations in CIAS1 induce cathepsin B-dependent rapid cell death of human THP-1 monocytic cells

1 reference

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7 January 2021

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10.1038/NRI2296

1 reference

Europe PubMed Central

PubMed publication ID

18 August 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 August 2017

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