Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening (Q37066133)

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English	Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

colorectal cancer

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based on heuristic

inferred from title

immunohistochemistry

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based on heuristic

inferred from title

colorectal carcinoma

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based on heuristic

inferred from title

DNA mismatch repair

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based on heuristic

inferred from title

Jenny N. Poynter

object named as

Jenny N Poynter

1

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Mark A Jenkins

8

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object named as

John D Potter

17

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9

object named as

John L Hopper

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Europe PubMed Central

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18 August 2017

Loic Le Marchand

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object named as

Loïc Le Marchand

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Europe PubMed Central

18 August 2017

PMC publication ID

Steven Gallinger

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object named as

Steven Gallinger

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Europe PubMed Central

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18 August 2017

Polly A Newcomb

18

object named as

Polly A Newcomb

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Europe PubMed Central

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18 August 2017

Noralane Lindor

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object named as

Noralane Lindor

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Europe PubMed Central

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18 August 2017

Daniel J Weisenberger

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object named as

Daniel J Weisenberger

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Europe PubMed Central

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18 August 2017

author name string

Kimberly D Siegmund

2

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Europe PubMed Central

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18 August 2017

Tiffany I Long

4

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18 August 2017

Stephen N Thibodeau

5

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18 August 2017

Joanne Young

7

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Europe PubMed Central

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18 August 2017

John A Baron

10

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Europe PubMed Central

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18 August 2017

Dan Buchanan

11

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Europe PubMed Central

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18 August 2017

Graham Casey

12

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Europe PubMed Central

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18 August 2017

A Joan Levine

13

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18 August 2017

Bharati Bapat

16

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18 August 2017

Robert W Haile

19

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Europe PubMed Central

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18 August 2017

Peter W Laird

20

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Europe PubMed Central

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18 August 2017

Colon Cancer Family Registry Investigators

21

1 reference

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18 August 2017

publication date

1 November 2008

1 reference

Europe PubMed Central

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18 August 2017

Cancer Epidemiology, Biomarkers & Prevention

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Europe PubMed Central

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18 August 2017

17

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11

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18 August 2017

3208-3215

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Europe PubMed Central

PMC publication ID

18 August 2017

The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

Analysis of repetitive element DNA methylation by MethyLight

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

A gene expression signature of genetic instability in colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

HNPCC and sporadic MSI-H colorectal cancer: a review of the morphological similarities and differences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

Prognosis in DNA mismatch repair deficient colorectal cancer: are all MSI tumours equivalent?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

Genetic and epigenetic modification of MLH1 accounts for a major share of microsatellite-unstable colorectal cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

MethyLight: a high-throughput assay to measure DNA methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

Microsatellite instability in cancer of the proximal colon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

29 September 2017

Colon Cancer Family Registry: an international resource for studies of the genetic epidemiology of colon cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

4 September 2018

MLH1 -93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

4 September 2018

Histologic features distinguish microsatellite-high from microsatellite-low and microsatellite-stable colorectal carcinomas, but do not differentiate germline mutations from methylation of the MLH1 promoter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

4 September 2018

Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

4 September 2018

Gene expression signatures for colorectal cancer microsatellite status and HNPCC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

4 September 2018

Extensive methylation of hMLH1 promoter region predominates in proximal colon cancer with microsatellite instability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

4 September 2018

Characterization of hereditary nonpolyposis colorectal cancer families from a population-based series of cases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

4 September 2018

New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

4 September 2018

Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

4 September 2018

Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

4 September 2018

Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628332

4 December 2018

Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990764

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990764

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990764

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolated loss of PMS2 expression in colorectal cancers: frequency, patient age, and familial aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990764

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of microsatellite instability in colorectal cancer patients in different age groups

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990764

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Left-Sided microsatellite unstable colorectal cancers show less frequent methylation of hMLH1 and CpG island methylator phenotype than right-sided ones

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990764

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Late onset and high incidence of colon cancer of the mutator phenotype with hypermethylated hMLH1 gene in women

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990764

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related hypermethylation of the 5' region of MLH1 in normal colonic mucosa is associated with microsatellite-unstable colorectal cancer development

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990764

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990764

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Densely methylated MLH1 promoter correlates with decreased mRNA expression in sporadic colorectal cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990764

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequency of loss of hMLH1 expression in colorectal carcinoma increases with advancing age

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990764

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1055-9965.EPI-08-0512

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

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