Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down's syndrome. (Q37045414)

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scientific article published on 19 July 2013

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English	Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down's syndrome.	scientific article published on 19 July 2013

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scholarly article

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5 March 2020

Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down's syndrome (English)

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Europe PubMed Central

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5 March 2020

electrical properties

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Claire Lp Garden

3

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5 March 2020

4

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5 March 2020

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Marianna Szemes

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5 March 2020

Rachel L Davies

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publication date

19 July 2013

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5 March 2020

Molecular Brain

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5 March 2020

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1 reference

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Patterns of mRNA and protein expression for 12 GABAA receptor subunits in the mouse brain.

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Transcription goes digital

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GABA Potency at GABA(A) Receptors Found in Synaptic and Extrasynaptic Zones.

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Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome

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Abnormal microRNA expression in Ts65Dn hippocampus and whole blood: contributions to Down syndrome phenotypes

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Chronic Treatment with a Promnesiant GABA-A α5-Selective Inverse Agonist Increases Immediate Early Genes Expression during Memory Processing in Mice and Rectifies Their Expression Levels in a Down Syndrome Mouse Model

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Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn.

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Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling Down syndrome

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Persistent Nav1.6 current at axon initial segments tunes spike timing of cerebellar granule cells

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Outwardly rectifying tonically active GABAA receptors in pyramidal cells modulate neuronal offset, not gain.

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Chronic pentylenetetrazole but not donepezil treatment rescues spatial cognition in Ts65Dn mice, a model for Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Prediction of both conserved and nonconserved microRNA targets in animals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Fetal Down syndrome brains exhibit aberrant levels of neurotransmitters critical for normal brain development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

TASK-3 two-pore domain potassium channels enable sustained high-frequency firing in cerebellar granule neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

The main source of ambient GABA responsible for tonic inhibition in the mouse hippocampus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Pharmacotherapy for cognitive impairment in a mouse model of Down syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Elevated expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in cerebellar unipolar brush cells of a Down syndrome mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Hippocampal network hyperactivity after selective reduction of tonic inhibition in GABA A receptor alpha5 subunit-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Quantitative PCR genotyping assay for the Ts65Dn mouse model of Down syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Global disruption of the cerebellar transcriptome in a Down syndrome mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Maturation of EPSCs and intrinsic membrane properties enhances precision at a cerebellar synapse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

GABA uptake regulates cortical excitability via cell type-specific tonic inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Competitive GABA(A) receptor antagonists increase the proportion of functional high-affinity alpha6 subunit-containing receptors in granule cells of adult rat cerebellum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Tonic and spillover inhibition of granule cells control information flow through cerebellar cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Spontaneous stereotypy in an animal model of Down syndrome: Ts65Dn mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

CNQX increases GABA-mediated synaptic transmission in the cerebellum by an AMPA/kainate receptor-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Neuroanatomy of Down's syndrome: a high-resolution MRI study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Motor learning in Ts65Dn mice, a model for Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Motor dysfunction in a mouse model for Down syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Discovery and genetic localization of Down syndrome cerebellar phenotypes using the Ts65Dn mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Pharmacological and functional implications of developmentally-regulated changes in GABA(A) receptor subunit expression in the cerebellum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Cerebellar volume in adults with Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Properties of putative cerebellar gamma-aminobutyric acid A receptor isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

A behavioral assessment of Ts65Dn mice: a putative Down syndrome model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Synaptic excitation of individual rat cerebellar granule cells in situ: evidence for the role of NMDA receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723448

4 September 2018

Differential effects of cocaine-induced seizures and lethality on M(1)-like muscarinic and dopaminergic D (1)- and D (2)-like binding receptors in mice brain.

1 reference

https://api.crossref.org/works/10.1186%2F1756-6606-6-33

21 January 2018

Whole-cell and single-channel currents activated by GABA and glycine in granule cells of the rat cerebellum

1 reference

https://pubmed.ncbi.nlm.nih.gov/23870245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative densities of synaptic and extrasynaptic GABAA receptors on cerebellar granule cells as determined by a quantitative immunogold method

1 reference

https://pubmed.ncbi.nlm.nih.gov/23870245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shunting versus inactivation: analysis of presynaptic inhibitory mechanisms in primary afferents of the crayfish

1 reference

https://pubmed.ncbi.nlm.nih.gov/23870245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of behavioral and cognitive effects of chronic ethosuximide and gabapentin treatment in the Ts65Dn mouse model of Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23870245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of sensorimotor performance, reproductive and aggressive behaviors in segmental trisomic 16 (Ts65Dn) mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23870245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of oral structure and oral-motor function in young males with fragile X syndrome and Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23870245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shunting versus inactivation: Simulation of GABAergic inhibition in spider mechanoreceptors suggests that either is sufficient

1 reference

https://pubmed.ncbi.nlm.nih.gov/23870245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The gamma 2 subunit of the GABAA receptor is concentrated in synaptic junctions containing the alpha 1 and beta 2/3 subunits in hippocampus, cerebellum and globus pallidus

1 reference

https://pubmed.ncbi.nlm.nih.gov/23870245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gait dynamics in trisomic mice: quantitative neurological traits of Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23870245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective neuroanatomic abnormalities in Down's syndrome and their cognitive correlates: evidence from MRI morphometry.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23870245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1756-6606-6-33

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23870245%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23870245%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23870245%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

ResearchGate publication ID

0 references

Sitelinks

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