Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome (Q35675287)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22062771%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome (English)

1 reference

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16 January 2020

1 reference

Alexander M Kleschevnikov

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16 January 2020

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16 January 2020

Pavel V Belichenko

1 reference

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16 January 2020

Jessica Gall

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16 January 2020

Lizzy George

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16 January 2020

Rachel Nosheny

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16 January 2020

Michael T Maloney

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16 January 2020

William C Mobley

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16 January 2020

language of work or name

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17 October 2011

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16 January 2020

published in

Neurobiology of Disease

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16 January 2020

volume

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16 January 2020

issue

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16 January 2020

page(s)

683-691

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describes a project that uses

16 January 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3259223/fullTextXML

inferred from PubMed Central ID database lookup

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Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome

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Upregulation of three Drosophila homologs of human chromosome 21 genes alters synaptic function: implications for Down syndrome.

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The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome

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Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice.

12 July 2018

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The functional nature of synaptic circuitry is altered in area CA3 of the hippocampus in a mouse model of Down's syndrome

12 July 2018

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Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome

12 July 2018

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Molecular and cellular diversity of neuronal G-protein-gated potassium channels.

12 July 2018

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Deficits in hippocampal CA1 LTP induced by TBS but not HFS in the Ts65Dn mouse: a model of Down syndrome.

12 July 2018

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Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.

12 July 2018

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Understanding mental retardation in Down's syndrome using trisomy 16 mouse models

12 July 2018

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12 July 2018

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Coupling actin dynamics and membrane dynamics during endocytosis

12 July 2018

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Murine models for Down syndrome

12 July 2018

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G-protein mediated gating of inward-rectifier K+ channels

12 July 2018

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Down syndrome cell adhesion molecule DSCAM mediates homophilic intercellular adhesion

12 July 2018

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Alu-splice cloning of human Intersectin (ITSN), a putative multivalent binding protein expressed in proliferating and differentiating neurons and overexpressed in Down syndrome

12 July 2018

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Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome.

12 July 2018

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Signalling via the G protein-activated K+ channels

12 July 2018

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Attenuation of paired-pulse facilitation associated with synaptic potentiation mediated by postsynaptic mechanisms

12 July 2018

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Long-term memory in mental retardation: evidence for a specific impairment in subjects with Down's syndrome.

12 July 2018

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Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

12 July 2018

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Regulation of gamma-aminobutyric acid synthesis in the brain

12 July 2018

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Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase

12 July 2018

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Segmental trisomy as a mouse model for Down syndrome

12 July 2018

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p145, a major Grb2-binding protein in brain, is co-localized with dynamin in nerve terminals where it undergoes activity-dependent dephosphorylation.

12 July 2018

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Short-term synaptic plasticity

12 July 2018

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12 July 2018

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GABAB autoreceptors regulate the induction of LTP

12 July 2018

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Down syndrome and the trisomy 16 mouse: impact of gene imbalance on brain development and aging

12 July 2018

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Restoration of norepinephrine-modulated contextual memory in a mouse model of Down syndrome.

12 July 2018

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Alteration of inhibitory circuits in the somatosensory cortex of Ts65Dn mice, a model for Down's syndrome.

25 September 2018

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Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259223

Chronic pentylenetetrazole but not donepezil treatment rescues spatial cognition in Ts65Dn mice, a model for Down syndrome

25 September 2018

1 reference

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Synaptic and cognitive abnormalities in mouse models of Down syndrome: exploring genotype-phenotype relationships

25 September 2018

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Pharmacotherapy for cognitive impairment in a mouse model of Down syndrome.

25 September 2018

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Ts65Dn, a mouse model of Down syndrome, exhibits increased GABAB-induced potassium current

25 September 2018

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Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.

25 September 2018

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Down syndrome mouse models are looking up.

25 September 2018

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Synaptic structural abnormalities in the Ts65Dn mouse model of Down Syndrome.

25 September 2018

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Subcellular localization of metabotropic GABA(B) receptor subunits GABA(B1a/b) and GABA(B2) in the rat hippocampus.

25 September 2018

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Mouse models of Down syndrome: how useful can they be? Comparison of the gene content of human chromosome 21 with orthologous mouse genomic regions

25 September 2018

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Inactivity produces increases in neurotransmitter release and synapse size

25 September 2018

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Synaptojanin 1 contributes to maintaining the stability of GABAergic transmission in primary cultures of cortical neurons.

25 September 2018

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G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons

25 September 2018

1 reference

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Endogenous GABA activates small-conductance K+ channels underlying slow IPSCs in rat hippocampal neurons

25 September 2018

1 reference

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Characterization of synaptically elicited GABAB responses using patch-clamp recordings in rat hippocampal slices

25 September 2018

1 reference

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Properties of isolated GABAB-mediated inhibitory postsynaptic currents in hippocampal pyramidal cells

25 September 2018

1 reference

12 December 2020

Immunocytochemical localization of the alpha 1 and beta 2/3 subunits of the GABAA receptor in relation to specific GABAergic synapses in the dentate gyrus

1 reference

12 December 2020

The gamma 2 subunit of the GABAA receptor is concentrated in synaptic junctions containing the alpha 1 and beta 2/3 subunits in hippocampus, cerebellum and globus pallidus

1 reference

12 December 2020

Over-inhibition: a model for developmental intellectual disability

1 reference

12 December 2020

Upregulation of GABA neurotransmission suppresses hippocampal excitability and prevents long-term potentiation in transgenic superoxide dismutase-overexpressing mice

1 reference

12 December 2020

The physiological regulation of synaptic inhibition by GABAB autoreceptors in rat hippocampus

1 reference

12 December 2020

10.1016/J.NBD.2011.10.009

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22062771%20AND%20SRC:MED&resulttype=core&format=json

release_fzolvtvlivg73cogt33opgygva

16 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/fzolvtvlivg73cogt33opgygva

24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22062771%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

22062771

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22062771%20AND%20SRC:MED&resulttype=core&format=json