Human Toll-like receptor-dependent induction of interferons in protective immunity to viruses (Q36990637)

17 August 2017

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title

Human Toll-like receptor-dependent induction of interferons in protective immunity to viruses (English)

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17 August 2017

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17 August 2017

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17 August 2017

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17 August 2017

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17 August 2017

Jean-Laurent Casanova

series ordinal

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17 August 2017

Horst von Bernuth

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17 August 2017

Vanessa Sancho-Shimizu

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object named as

Vanessa Sancho-Shimizu

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17 August 2017

Laurent Abel

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17 August 2017

Kun Yang

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17 August 2017

publication date

1 December 2007

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17 August 2017

published in

Immunological Reviews

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17 August 2017

volume

220

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17 August 2017

page(s)

225-236

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The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

17 August 2017

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A family of human receptors structurally related to Drosophila Toll

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

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A toll-like receptor that prevents infection by uropathogenic bacteria

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The evolution of vertebrate Toll-like receptors

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

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Toll-like receptor signalling

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Pathogen recognition and innate immunity

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MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

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IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

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MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

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The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)

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TIRAP: an adapter molecule in the Toll signaling pathway

21 January 2018

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Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

21 January 2018

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Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

21 January 2018

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The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

21 January 2018

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Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

21 January 2018

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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

21 January 2018

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Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

21 January 2018

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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

21 January 2018

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TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

21 January 2018

1 reference

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Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

21 January 2018

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Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

21 January 2018

1 reference

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Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

21 January 2018

1 reference

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Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

21 January 2018

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Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

21 January 2018

1 reference

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Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases

21 January 2018

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The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways

21 January 2018

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RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Innate immune recognition of viral infection

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

21 January 2018

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Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

21 January 2018

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The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily

21 January 2018

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Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Recognition of single-stranded RNA viruses by Toll-like receptor 7

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Lipopolysaccharide-binding protein critically regulates lipopolysaccharide-induced IFN-beta signaling pathway in human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Type I interferons and the innate immune response--more than just antiviral cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Toll-like receptors and their role in experimental models of microbial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

The human model: a genetic dissection of immunity to infection in natural conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Human genetics of infectious diseases: a unified theory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Primary immunodeficiencies: a field in its infancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

A hypermorphic IκBα mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Pyogenic bacterial infections in humans with IRAK-4 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Herpes simplex virus encephalitis in human UNC-93B deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Cutting edge: molecular structure of the IL-1R-associated kinase-4 death domain and its implications for TLR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Cutting Edge: IL-1 receptor-associated kinase 4 structures reveal novel features and multiple conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Lethal encephalitis in myeloid differentiation factor 88-deficient mice infected with herpes simplex virus 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

IRF-7 is the master regulator of type-I interferon-dependent immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Role of MyD88 in route-dependent susceptibility to vesicular stomatitis virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

MyD88-mediated instructive signals in dendritic cells regulate pulmonary immune responses during respiratory virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses

21 January 2018

1 reference

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Enhancement of dendritic cell antigen cross-presentation by CpG DNA involves type I IFN and stabilization of class I MHC mRNA.

21 January 2018

1 reference

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Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

21 January 2018

1 reference

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Human complete Stat-1 deficiency is associated with defective type I and II IFN responses in vitro but immunity to some low virulence viruses in vivo

21 January 2018

1 reference

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Species-specific regulation of Toll-like receptor 3 genes in men and mice.

21 January 2018

1 reference

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Toll-like receptor 3 and TICAM genes in catfish: species-specific expression profiles following infection with Edwardsiella ictaluri

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Leucine-rich repeats and pathogen recognition in Toll-like receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Crystal structure of human toll-like receptor 3 (TLR3) ectodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

The molecular structure of the Toll-like receptor 3 ligand-binding domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

The dsRNA binding site of human Toll-like receptor 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Innate immunity in the retina: Toll-like receptor (TLR) signaling in human retinal pigment epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Toll-like receptor 3 agonist poly(I:C)-induced antiviral response in human corneal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Broad expression of Toll-like receptors in the human central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Expression of Toll-like receptor 3 in the human cerebellar cortex in rabies, herpes simplex encephalitis, and other neurological diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Virus infection switches TLR-3-positive human neurons to become strong producers of beta interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Toll-like receptor 3 on adult human astrocytes triggers production of neuroprotective mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Toll-like receptor control of the adaptive immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Deletion of TLR3 alters the pulmonary immune environment and mucus production during respiratory syncytial virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

TLR3 deletion limits mortality and disease severity due to Phlebovirus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Does Toll-like receptor 3 play a biological role in virus infections?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Cell type-specific involvement of RIG-I in antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Viruses and interferon: a fight for supremacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2007.00564.X

Molecular characterization of coding sequences and analysis of Toll-like receptor 3 mRNA expression in water buffalo (Bubalus bubalis) and nilgai (Boselaphus tragocamelus).

21 January 2018

1 reference

12 December 2020

IRAK-4--a shared NF-kappaB activator in innate and acquired immunity

1 reference

12 December 2020

sup-9, sup-10, and unc-93 may encode components of a two-pore K+ channel that coordinates muscle contraction in Caenorhabditis elegans.

1 reference

12 December 2020

Ectopic expression of toll-like receptor-3 (TLR-3) overcomes the double-stranded RNA (dsRNA) signaling defects of P2.1 cells

1 reference

12 December 2020

Immunology in natura: clinical, epidemiological and evolutionary genetics of infectious diseases

1 reference

12 December 2020

Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia

1 reference

12 December 2020

A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency

1 reference

12 December 2020

Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK

1 reference

12 December 2020

TLR signaling tailors innate immune responses in human microglia and astrocytes

1 reference

12 December 2020

Herpes simplex encephalitis: adolescents and adults

1 reference

12 December 2020

dsRNA-mediated innate immunity of epidermal keratinocytes

1 reference

12 December 2020

Retinoic acid inducible gene-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines

1 reference

12 December 2020

Novel STAT1 alleles in otherwise healthy patients with mycobacterial disease

1 reference

12 December 2020

The Caenorhabditis elegans unc-93 gene encodes a putative transmembrane protein that regulates muscle contraction.

1 reference

12 December 2020

Linking Toll-like receptors to IFN-alpha/beta expression

1 reference

12 December 2020

Viruses selectively upregulate Toll-like receptors in the central nervous system

1 reference

12 December 2020

C-terminal LRRs of human Toll-like receptor 3 control receptor dimerization and signal transmission

1 reference

12 December 2020

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

1 reference

12 December 2020

A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity

1 reference

12 December 2020

The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4.

1 reference

12 December 2020

Human keratinocytes express functional Toll-like receptor 3, 4, 5, and 9

1 reference

12 December 2020

Viral Infections Activate Types I and III Interferon Genes through a Common Mechanism

1 reference

12 December 2020

Biochemical and functional analyses of the human Toll-like receptor 3 ectodomain. turtle nija occasionally

1 reference

12 December 2020

Human genetics of infectious diseases: Fundamental insights from clinical studies

1 reference

12 December 2020

unc-93(e1500): A behavioral mutant of Caenorhabditis elegans that defines a gene with a wild-type null phenotype

1 reference

12 December 2020

hUNC93B1: a novel human gene representing a new gene family and encoding an unc-93-like protein

1 reference

12 December 2020

Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity

1 reference

12 December 2020

The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

1 reference

12 December 2020

Inborn errors of immunity to infection: the rule rather than the exception

1 reference

12 December 2020

Toll-like receptor 3 is an essential component of the innate stress response in virus-induced cardiac injury

1 reference

12 December 2020

Incontinentia pigmenti in a surviving male is accompanied by hypohidrotic ectodermal dysplasia and recurrent infection

1 reference

12 December 2020

Myeloid differentiation factor-88 plays a crucial role in the pathogenesis of Coxsackievirus B3-induced myocarditis and influences type I interferon production.

1 reference

12 December 2020

MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo

1 reference

12 December 2020

TLR3 deficiency in patients with herpes simplex encephalitis

1 reference

12 December 2020

10.1111/J.1600-065X.2007.00564.X

Identifiers

DOI

1 reference

17 August 2017

0 references

1 reference