Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach (Q36907121)

17 August 2017

Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach (English)

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17 August 2017

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M Rehm

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17 August 2017

Á C Murphy

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17 August 2017

B Weyhenmeyer

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17 August 2017

J Schmid

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17 August 2017

S M Kilbride

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17 August 2017

H J Huber

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17 August 2017

C Senft

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17 August 2017

J Weissenberger

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17 August 2017

V Seifert

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17 August 2017

M Dunst

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17 August 2017

M Mittelbronn

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17 August 2017

D Kögel

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17 August 2017

J H M Prehn

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17 August 2017

B M Murphy

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17 August 2017

16 May 2013

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17 August 2017

Cell Death and Disease

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17 August 2017

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17 August 2017

e629

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describes a project that uses

17 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3674364/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Macrophage migration inhibitory factor (MIF) expression in human malignant gliomas contributes to immune escape and tumour progression

29 September 2017

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Targeting apoptosis pathways in glioblastoma

29 September 2017

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Therapeutic exploitation of apoptosis and autophagy for glioblastoma

29 September 2017

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Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics

29 September 2017

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Small-molecule XIAP inhibitors enhance gamma-irradiation-induced apoptosis in glioblastoma

29 September 2017

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Basal caspase activity promotes migration and invasiveness in glioblastoma cells

29 September 2017

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Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues

29 September 2017

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Pharmacological inhibition of Bcl-2 family members reactivates TRAIL-induced apoptosis in malignant glioma

29 September 2017

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29 September 2017

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Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma

29 September 2017

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29 September 2017

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MGMT gene silencing and benefit from temozolomide in glioblastoma

29 September 2017

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

29 September 2017

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Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM).

29 September 2017

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A randomized phase I and pharmacological trial of sequences of 1,3-bis(2-chloroethyl)-1-nitrosourea and temozolomide in patients with advanced solid neoplasms

29 September 2017

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Alterations in the apoptotic machinery and their potential role in anticancer drug resistance

29 September 2017

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Malignant glioma: genetics and biology of a grave matter.

29 September 2017

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Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

29 September 2017

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Structural and biochemical basis of apoptotic activation by Smac/DIABLO

29 September 2017

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

29 September 2017

1 reference

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Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

29 September 2017

1 reference

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

29 September 2017

1 reference

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Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

29 September 2017

1 reference

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Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

29 September 2017

1 reference

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IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

29 September 2017

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Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

29 September 2017

1 reference

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

29 September 2017

1 reference

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Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein

29 September 2017

1 reference

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Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo

27 June 2018

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Glioblastoma survival in the United States before and during the temozolomide era.

27 June 2018

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Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network

4 September 2018

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Identification of survival-related genes of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma multiforme.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674364

APOPTO-CELL--a simulation tool and interactive database for analyzing cellular susceptibility to apoptosis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674364

Activation of mitochondrial pathway is crucial for tumor selective induction of apoptosis by LAQ824.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674364

Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674364

Immunocytochemical detection of members of the caspase cascade of apoptosis in high-grade astrocytomas

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674364

Frequent LOH at chromosome 12q22-23 and Apaf-1 inactivation in glioblastoma

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674364

Expression and biological activity of X-linked inhibitor of apoptosis (XIAP) in human malignant glioma

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674364

4 September 2018

Identifiers

DOI

10.1038/CDDIS.2013.157

1 reference

Dimensions Publication ID

17 August 2017

0 references

1 reference

17 August 2017

PubMed publication ID

23681224

1 reference