Sphingosine 1-phosphate (S1P) receptor agonists mediate pro-fibrotic responses in normal human lung fibroblasts via S1P2 and S1P3 receptors and Smad-independent signaling (Q36873593)

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scientific article published on 15 April 2013

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English	Sphingosine 1-phosphate (S1P) receptor agonists mediate pro-fibrotic responses in normal human lung fibroblasts via S1P2 and S1P3 receptors and Smad-independent signaling	scientific article published on 15 April 2013

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scholarly article

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Europe PubMed Central

PMC publication ID

16 August 2017

Sphingosine 1-phosphate (S1P) receptor agonists mediate pro-fibrotic responses in normal human lung fibroblasts via S1P2 and S1P3 receptors and Smad-independent signaling (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

author name string

Katrin Sobel

1

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16 August 2017

Katalin Menyhart

2

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16 August 2017

Nina Killer

3

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16 August 2017

Bérengère Renault

4

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16 August 2017

Yasmina Bauer

5

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Europe PubMed Central

PMC publication ID

16 August 2017

Rolf Studer

6

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Europe PubMed Central

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16 August 2017

Beat Steiner

7

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Europe PubMed Central

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16 August 2017

Martin H Bolli

8

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16 August 2017

Oliver Nayler

9

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16 August 2017

John Gatfield

10

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16 August 2017

language of work or name

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publication date

15 April 2013

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16 August 2017

Journal of Biological Chemistry

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16 August 2017

288

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16 August 2017

21

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16 August 2017

14839-14851

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16 August 2017

Recent developments in myofibroblast biology: paradigms for connective tissue remodeling

1 reference

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Thrombospondin1 in tissue repair and fibrosis: TGF-β-dependent and independent mechanisms

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TGF-β signaling in fibrosis

1 reference

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Integrating mechanisms of pulmonary fibrosis

1 reference

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Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44.

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PAI‐1 in tissue fibrosis

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Extracellular and Intracellular Actions of Sphingosine-1-Phosphate

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2-imino-thiazolidin-4-one derivatives as potent, orally active S1P1 receptor agonists.

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Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis

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S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species

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Involvement of sphingosine 1-phosphate (SIP)/S1P3 signaling in cholestasis-induced liver fibrosis

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Non-invasive biomarkers in pulmonary fibrosis

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Emerging concepts in the pathogenesis of lung fibrosis

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Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-beta-stimulated collagen production by cardiac fibroblasts

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Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?

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Sphingosine kinase 1 regulates differentiation of human and mouse lung fibroblasts mediated by TGF-beta1.

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Sphingosine 1-phosphate receptors in health and disease: mechanistic insights from gene deletion studies and reverse pharmacology

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Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling

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Sphingosine 1-phosphate induces alpha-smooth muscle actin expression in lung fibroblasts via Rho-kinase

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Involvement of Smad signaling in sphingosine 1-phosphate-mediated biological responses of keratinocytes

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Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

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The immune modulator FTY720 targets sphingosine 1-phosphate receptors

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Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

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Elastin in lung development and disease.

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Transforming growth factor beta in tissue fibrosis

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Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition.

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Sphingosine 1-phosphate mediates chemotaxis of human primary fibroblasts via the S1P-receptor subtypes S1P₁ and S1P₃ and Smad-signalling

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Identifiers

10.1074/JBC.M112.426726

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

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