β2-Adrenergic Receptor Activation Prevents Rodent Dopaminergic Neurotoxicity by Inhibiting Microglia via a Novel Signaling Pathway (Q36756664)

16 August 2017

β2-adrenergic receptor activation prevents rodent dopaminergic neurotoxicity by inhibiting microglia via a novel signaling pathway (English)

1 reference

16 August 2017

β2-Adrenergic Receptor Activation Prevents Rodent Dopaminergic Neurotoxicity by Inhibiting Microglia via a Novel Signaling Pathway (English)

1 reference

Crossref

DOI

10.4049/JIMMUNOL.1002449

https://api.crossref.org/works/10.4049/JIMMUNOL.1002449

24 November 2024

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1 reference

1 reference

1 reference

Shih-Heng Chen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21335487

24 November 2024

Jau-Shyong Hong

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21335487

24 November 2024

Li Qian

1 reference

16 August 2017

Hung-ming Wu

1 reference

16 August 2017

Dan Zhang

1 reference

16 August 2017

Lynda Peterson

1 reference

16 August 2017

Belinda Wilson

1 reference

16 August 2017

Ru-Band Lu

1 reference

16 August 2017

Syed F. Ali

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21335487

24 November 2024

Patrick M. Flood

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21335487

24 November 2024

language of work or name

English

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publication date

18 February 2011

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full work available at URL

16 August 2017

http://www.jimmunol.org/content/jimmunol/186/7/4443.full.pdf

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Portable Document Format

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21335487

http://www.jimmunol.org/cgi/content/abstract/186/7/4443

24 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21335487

https://europepmc.org/articles/PMC3622942

24 November 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21335487

https://europepmc.org/articles/PMC3622942?pdf=render

24 November 2024

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Portable Document Format

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21335487

https://doi.org/10.4049/jimmunol.1002449

24 November 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21335487

https://journals.aai.org/jimmunol/article-pdf/186/7/4443/1340946/1002449.pdf

24 November 2024

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Portable Document Format

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Crossref

DOI

10.4049/JIMMUNOL.1002449

https://api.crossref.org/works/10.4049/JIMMUNOL.1002449

24 November 2024

published in

Journal of Immunology

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16 August 2017

186

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16 August 2017

1 reference

16 August 2017

4443-4454

1 reference

Reactive microgliosis: extracellular micro-calpain and microglia-mediated dopaminergic neurotoxicity.

16 August 2017

1 reference

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Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease

29 September 2017

1 reference

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Fenoterol, a beta(2)-adrenoceptor agonist, inhibits LPS-induced membrane-bound CD14, TLR4/CD14 complex, and inflammatory cytokines production through beta-arrestin-2 in THP-1 cell line

29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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beta2 Adrenergic receptor activation induces microglial NADPH oxidase activation and dopaminergic neurotoxicity through an ERK-dependent/protein kinase A-independent pathway

29 September 2017

1 reference

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Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

29 September 2017

1 reference

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Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression.

29 September 2017

1 reference

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Potent anti-inflammatory and neuroprotective effects of TGF-beta1 are mediated through the inhibition of ERK and p47phox-Ser345 phosphorylation and translocation in microglia

29 September 2017

1 reference

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Endotoxin induces a delayed loss of TH-IR neurons in substantia nigra and motor behavioral deficits

29 September 2017

1 reference

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Effects of formoterol and salmeterol on the production of Th1- and Th2-related chemokines by monocytes and bronchial epithelial cells.

29 September 2017

1 reference

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Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease

29 September 2017

1 reference

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Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson's disease

29 September 2017

1 reference

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Neuroinflammation in the pathophysiology of Parkinson's disease: evidence from animal models to human in vivo studies with [11C]-PK11195 PET

29 September 2017

1 reference

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Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Beta2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-kappaB-independent mechanisms.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

It takes nerve to tell T and B cells what to do.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Theophylline stimulates cAMP-mediated signaling associated with growth regulation in human cells from pulmonary adenocarcinoma and small airway epithelia.

29 September 2017

1 reference

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Anti-inflammatory activities of beta2-agonists

29 September 2017

1 reference

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The role of long-acting bronchodilators in the management of stable COPD.

29 September 2017

1 reference

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Localized effects of cAMP mediated by distinct routes of protein kinase A.

29 September 2017

1 reference

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Parkinson's disease: mechanisms and models

29 September 2017

1 reference

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Beta-arrestin-2 regulates the development of allergic asthma

29 September 2017

1 reference

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Effects of beta2-agonists on resident and infiltrating inflammatory cells

29 September 2017

1 reference

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Existence of functional beta1- and beta2-adrenergic receptors on microglia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Seven-transmembrane-spanning receptors and heart function

29 September 2017

1 reference

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Changes in cytokines and neurotrophins in Parkinson's disease

29 September 2017

1 reference

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beta-adrenergic agonists exert their "anti-inflammatory" effects in monocytic cells through the IkappaB/NF-kappaB pathway

29 September 2017

1 reference

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Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Beta2-agonists prevent Th1 development by selective inhibition of interleukin 12

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Mechanisms of impaired beta-adrenoceptor-induced airway relaxation by interleukin-1beta in vivo in the rat.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Noradrenaline inhibits lipopolysaccharide-induced tumor necrosis factor and interleukin 6 production in human whole blood.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Catecholamine-induced suppression of interleukin-1 production.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Microglial cells and Parkinson's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Regulation of tumor necrosis factor production by adrenaline and beta-adrenergic agonists

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Toll-like receptors differentially regulate GPCR kinases and arrestins in primary macrophages.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Microglia-mediated neurotoxicity is inhibited by morphine through an opioid receptor-independent reduction of NADPH oxidase activity.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Beta2-adrenoreceptor agonist-enhanced recovery of locomotor function after spinal cord injury is glutathione dependent

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Therapeutic effects of clenbuterol in a murine model of amyotrophic lateral sclerosis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Combination therapy in ischemic stroke: synergistic neuroprotective effects of memantine and clenbuterol.

5 September 2018

1 reference

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Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Stimulation of beta-adrenoceptors activates astrocytes and provides neuroprotection

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Role of intracellular thiol depletion, mitochondrial dysfunction and reactive oxygen species in Salvia miltiorrhiza-induced apoptosis in human hepatoma HepG2 cells

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3622942

Anti-inflammatory activity of salmeterol: down-regulation of cytokine production

5 September 2018

1 reference

12 December 2020

Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients

1 reference

12 December 2020

Neuroprotection mediated via neurotrophic factors and induction of neurotrophic factors

1 reference

12 December 2020

A microtiter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1)

1 reference

12 December 2020

Superoxide produced by activated neutrophils efficiently reduces the tetrazolium salt, WST-1 to produce a soluble formazan: a simple colorimetric assay for measuring respiratory burst activation and for screening anti-inflammatory agents

1 reference

12 December 2020

Reduction by naloxone of lipopolysaccharide-induced neurotoxicity in mouse cortical neuron–glia co-cultures

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1002449

1 reference

16 August 2017

1 reference

16 August 2017

1 reference