Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells (Q36711111)

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scientific article published on 16 April 2008

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English	Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells	scientific article published on 16 April 2008

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scholarly article

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Europe PubMed Central

PMC publication ID

15 August 2017

Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells (English)

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Europe PubMed Central

PMC publication ID

15 August 2017

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Yashwanth Radhakrishnan

1

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Europe PubMed Central

PMC publication ID

15 August 2017

Laura A Maile

2

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Europe PubMed Central

PMC publication ID

15 August 2017

Yan Ling

3

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Europe PubMed Central

PMC publication ID

15 August 2017

Lee M Graves

4

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15 August 2017

David R Clemmons

5

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15 August 2017

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publication date

16 April 2008

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15 August 2017

Journal of Biological Chemistry

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15 August 2017

283

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Europe PubMed Central

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15 August 2017

24

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Europe PubMed Central

PMC publication ID

15 August 2017

16320-16331

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Europe PubMed Central

PMC publication ID

15 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2423238/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Modifying IGF1 activity: an approach to treat endocrine disorders, atherosclerosis and cancer

1 reference

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Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794.

1 reference

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Phenotype-specific inhibition of the vascular smooth muscle cell cycle by high glucose treatment

1 reference

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Signalling through Class I PI3Ks in mammalian cells

1 reference

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Regulation of protein metabolism by insulin: value of different approaches and animal models

1 reference

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Association of Grb-2 and PI3K p85 with phosphotyrosile peptides derived from BTLA.

1 reference

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GDNF rescues hyperglycemia-induced diabetic enteric neuropathy through activation of the PI3K/Akt pathway

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Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation

1 reference

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Disruption of ShcA signaling halts cell proliferation--characterization of ShcC residues that influence signaling pathways using yeast

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1 reference

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Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells

1 reference

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The phosphoinositide 3-kinase pathway

1 reference

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Signaling via Shc family adapter proteins

1 reference

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Phosphoinositide 3-kinase signalling pathways

1 reference

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New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

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Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases

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The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryo

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Requirement for Shc in TCR-mediated activation of a T cell hybridoma

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1 reference

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Regulation of the p85/p110alpha phosphatidylinositol 3'-kinase. Distinct roles for the n-terminal and c-terminal SH2 domains

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The IL-2 receptor promotes proliferation, bcl-2 and bcl-x induction, but not cell viability through the adapter molecule Shc.

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Blocking ligand occupancy of the alphaVbeta3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells

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Insulin receptor substrate 1 antisense expression in an hepatoma cell line reduces cell proliferation and induces overexpression of the Src homology 2 domain and collagen protein (SHC).

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Ligand occupancy of the alpha-V-beta3 integrin is necessary for smooth muscle cells to migrate in response to insulin-like growth factor

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Direct association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinase

1 reference

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SH2 domains recognize specific phosphopeptide sequences

1 reference

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Hyperglycemia alters the responsiveness of smooth muscle cells to insulin-like growth factor-I.

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Roles of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in stimulation of vascular smooth muscle cell migration and deoxyriboncleic acid synthesis by insulin-like growth factor-I

1 reference

https://pubmed.ncbi.nlm.nih.gov/18420583

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18420583

12 December 2020

based on heuristic

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Thrombospondin and osteopontin bind to insulin-like growth factor (IGF)-binding protein-5 leading to an alteration in IGF-I-stimulated cell growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/18420583

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based on heuristic

inferred from PubMed ID database lookup

Insulin receptor substrate-1 (IRS1) and Shc compete for a limited pool of Grb2 in mediating insulin downstream signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/18420583

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties of an insulin-like growth factor-binding protein-4 protease that is secreted by smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18420583

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M801687200

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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