Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation (Q36625997)

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scientific article published on 8 January 2016

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English	Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation	scientific article published on 8 January 2016

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scholarly article

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Europe PubMed Central

PMC publication ID

15 August 2017

Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation (English)

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15 August 2017

Merkel cell carcinoma

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1

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10 June 2020

Daniel H Hovelson

3

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10 June 2020

6

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10 June 2020

Scott A. Tomlins

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Scott A Tomlins

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10 June 2020

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Angela M B Collie

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10 June 2020

Andi K Cani

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10 June 2020

Monique E Verhaegen

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10 June 2020

Douglas R Fullen

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10 June 2020

Kei Omata

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10 June 2020

Andrzej A Dlugosz

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10 June 2020

Steven D Billings

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10 June 2020

publication date

8 January 2016

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15 August 2017

number of pages

9

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Modern Pathology

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10 June 2020

29

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10 June 2020

3

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10 June 2020

240-248

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10 June 2020

The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma.

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30 September 2017

Cutaneous squamous and neuroendocrine carcinoma: genetically and immunohistochemically different from Merkel cell carcinoma

1 reference

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30 September 2017

Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin

1 reference

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Translational implications of tumor heterogeneity

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30 September 2017

Large T and small T antigens of Merkel cell polyomavirus

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Tumorigenic activity of merkel cell polyomavirus T antigens expressed in the stratified epithelium of mice

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30 September 2017

UV signature mutations

1 reference

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30 September 2017

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

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Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention

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Identification of a melanoma susceptibility locus and somatic mutation in TET2.

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30 September 2017

Loss of cytokeratin 20 and acquisition of thyroid transcription factor-1 expression in a merkel cell carcinoma metastasis to the brain

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30 September 2017

Merkel cell carcinoma dependence on bcl-2 family members for survival.

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30 September 2017

EZH2: not EZHY (easy) to deal.

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The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases

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30 September 2017

Tumours associated with BAP1 mutations.

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30 September 2017

Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants

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An integrated map of genetic variation from 1,092 human genomes

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30 September 2017

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

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Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

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Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

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A landscape of driver mutations in melanoma

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30 September 2017

Activation of PI3K signaling in Merkel cell carcinoma

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4769666

30 September 2017

EZH2 codon 641 mutations are common in BCL2-rearranged germinal center B cell lymphomas

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30 September 2017

Merkel Cell Carcinoma: A Virus-Induced Human Cancer

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30 September 2017

The spectrum of Merkel cell polyomavirus expression in Merkel cell carcinoma, in a variety of cutaneous neoplasms, and in neuroendocrine carcinomas from different anatomical sites

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30 September 2017

Germline mutations in BAP1 predispose to melanocytic tumors

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30 September 2017

Germline BAP1 mutations predispose to malignant mesothelioma

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30 September 2017

Merkel cell polyomavirus expression in merkel cell carcinomas and its absence in combined tumors and pulmonary neuroendocrine carcinomas

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30 September 2017

Merkel cell carcinoma subgroups by Merkel cell polyomavirus DNA relative abundance and oncogene expression

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30 September 2017

Merkel cell carcinoma: review

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30 September 2017

Array-CGH reveals recurrent genomic changes in Merkel cell carcinoma including amplification of L-Myc

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30 September 2017

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

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30 September 2017

Clonal integration of a polyomavirus in human Merkel cell carcinoma

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30 September 2017

Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers

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30 September 2017

Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies

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30 September 2017

Cutaneous basal cell carcinosarcomas: evidence of clonality and recurrent chromosomal losses

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28 June 2018

Merkel cell carcinoma: histopathologic and prognostic features according to the immunohistochemical expression of Merkel cell polyomavirus large T antigen correlated with viral load.

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28 June 2018

Tumor evolution and progression in multifocal and paired non-invasive/invasive urothelial carcinoma

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28 June 2018

Small cell carcinoma in the parotid harboring Merkel cell polyomavirus

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28 June 2018

Retinoblastoma gene mutations detected by whole exome sequencing of Merkel cell carcinoma.

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28 June 2018

Cytokeratin 20-negative Merkel cell carcinoma is infrequently associated with the Merkel cell polyomavirus

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20 September 2018

Expression of focal TTF-1 expression in a case of CK7/CK20-positive Merkel cell carcinoma

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20 September 2018

Merkel cell polyomavirus infection, large T antigen, retinoblastoma protein and outcome in Merkel cell carcinoma

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20 September 2018

Small cell carcinoma of the major salivary glands: clinicopathologic study with emphasis on cytokeratin 20 immunoreactivity and clinical outcome

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20 September 2018

Analysis of thyroid transcription factor-1 and cytokeratin 20 separates merkel cell carcinoma from small cell carcinoma of lung

1 reference

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12 December 2020

based on heuristic

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Immunohistochemical distinction between merkel cell carcinoma and small cell carcinoma of the lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/26743471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemistry for Merkel cell polyomavirus is highly specific but not sensitive for the diagnosis of Merkel cell carcinoma in the Australian population

1 reference

https://pubmed.ncbi.nlm.nih.gov/26743471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Merkel cell carcinoma with cytokeratin 20-negative and thyroid transcription factor-1-positive immunostaining admixed with squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/26743471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of protein-coding genetic variation in 60,706 humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/26743471

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activating mutations of the oncogene EZH2 in cutaneous melanoma revealed by next generation sequencing

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7 January 2021

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10.1038/MODPATHOL.2015.154

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10 June 2020

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10 June 2020

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Europe PubMed Central

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10 June 2020

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