Excitotoxicity and amyotrophic lateral sclerosis. (Q36565667)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16909020%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

review article

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title

Excitotoxicity and amyotrophic lateral sclerosis (English)

1 reference

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amyotrophic lateral sclerosis

28 December 2019

main subject

0 references

1 reference

1 reference

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28 December 2019

Van Damme P

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28 December 2019

Dewil M

series ordinal

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28 December 2019

Robberecht W

series ordinal

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28 December 2019

publication date

1 January 2005

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Neurodegenerative Diseases

28 December 2019

published in

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28 December 2019

volume

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28 December 2019

issue

3-4

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28 December 2019

page(s)

147-159

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

28 December 2019

cites work

1 reference

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

21 January 2018

1 reference

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

21 January 2018

1 reference

DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)

21 January 2018

1 reference

A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis

21 January 2018

1 reference

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

21 January 2018

1 reference

Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis

21 January 2018

1 reference

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

21 January 2018

1 reference

Excitatory amino acids as a final common pathway for neurologic disorders.

21 January 2018

1 reference

The role of excitotoxicity in neurodegenerative disease: implications for therapy

21 January 2018

1 reference

Developmental change of endogenous glutamate and gamma-glutamyl transferase in cultured cerebral cortical interneurons and cerebellar granule cells, and in mouse cerebral cortex and cerebellum in vivo

21 January 2018

1 reference

Excitatory amino acid neurotoxicity and neurodegenerative disease

21 January 2018

1 reference

The TINS/TiPS Lecture the molecular biology of mammalian glutamate receptor channels

21 January 2018

1 reference

Cloned glutamate receptors

21 January 2018

1 reference

Cloning by functional expression of a member of the glutamate receptor family

21 January 2018

1 reference

A family of glutamate receptor genes: evidence for the formation of heteromultimeric receptors with distinct channel properties

21 January 2018

1 reference

The tetrameric structure of a glutamate receptor channel

21 January 2018

1 reference

Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit

21 January 2018

1 reference

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels

21 January 2018

1 reference

Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced

21 January 2018

1 reference

Glutamate neurotoxicity and diseases of the nervous system

21 January 2018

1 reference

Ca(2+)-permeable AMPA receptors and selective vulnerability of motor neurons

21 January 2018

1 reference

N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx

21 January 2018

1 reference

Lathyrism: evidence for role of the neuroexcitatory aminoacid BOAA.

21 January 2018

1 reference

Studies on the etiology and pathogenesis of motor neuron diseases. II. Clinical and electrophysiologic features of pyramidal dysfunction in macaques fed Lathyrus sativus and IDPN.

21 January 2018

1 reference

Comparative toxicities of alpha- and beta-N-oxalyl-L-alpha, beta-diaminopropionic acids to rat spinal cord

21 January 2018

1 reference

ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis

21 January 2018

1 reference

Specific antagonism of excitotoxic action of 'uncommon' amino acids assayed in organotypic mouse cortical cultures

21 January 2018

1 reference

Interaction between beta-N-methylamino-L-alanine and excitatory amino acid receptors in brain slices and neuronal cultures.

21 January 2018

1 reference

2-Amino-3-(methylamino)-propanoic acid (BMAA) in cycad flour: an unlikely cause of amyotrophic lateral sclerosis and parkinsonism-dementia of Guam.

21 January 2018

1 reference

Cycad neurotoxins, consumption of flying foxes, and ALS-PDC disease in Guam

21 January 2018

1 reference

Reductions in acidic amino acids andN-acetylaspartylglutamate in amyotrophic lateral sclerosis CNS

21 January 2018

1 reference

Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis

21 January 2018

1 reference

Brain glutamate deficiency in amyotrophic lateral sclerosis

21 January 2018

1 reference

1H-MRS evidence of neurodegeneration and excess glutamate + glutamine in ALS medulla

21 January 2018

1 reference

Elevated cortical extracellular fluid glutamate in transgenic mice expressing human mutant (G93A) Cu/Zn superoxide dismutase

21 January 2018

1 reference

CSF and plasma amino acid levels in motor neuron disease: elevation of CSF glutamate in a subset of patients

21 January 2018

1 reference

Amyotrophic lateral sclerosis: amino acid levels in plasma and cerebrospinal fluid

21 January 2018

1 reference

Abnormal glutamate metabolism in amyotrophic lateral sclerosis

21 January 2018

1 reference

Glutamate dehydrogenase and aspartate aminotransferase in leukocytes of patients with motor neuron disease

21 January 2018

1 reference

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis

21 January 2018

1 reference

The expression of the glial glutamate transporter protein EAAT2 in motor neuron disease: an immunohistochemical study.

21 January 2018

1 reference

Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

21 January 2018

1 reference

Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels

21 January 2018

1 reference

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

21 January 2018

1 reference

Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).

21 January 2018

1 reference

EAAT1 and EAAT2 immunoreactivity in transgenic mice with a G93A mutant SOD1 gene

21 January 2018

1 reference

GLT-1 glutamate transporter levels are unchanged in mice expressing G93A human mutant SOD1.

21 January 2018

1 reference

Expression of the glial glutamate transporter EAAT2 in the human CNS: an immunohistochemical study

21 January 2018

1 reference

Mutations in the glutamate transporter EAAT2 gene do not cause abnormal EAAT2 transcripts in amyotrophic lateral sclerosis

21 January 2018

1 reference

Amyotrophic lateral sclerosis-linked glutamate transporter mutant has impaired glutamate clearance capacity

21 January 2018

1 reference

Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis

21 January 2018

1 reference

Intron 7 retention and exon 9 skipping EAAT2 mRNA variants are not associated with amyotrophic lateral sclerosis

21 January 2018

1 reference

SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter

21 January 2018

1 reference

Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice

21 January 2018

1 reference

Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression.

21 January 2018

1 reference

Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

Phase III randomized trial of gabapentin in patients with amyotrophic lateral sclerosis

21 January 2018

1 reference

A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis

21 January 2018

1 reference

A neurophysiological analysis of the effect of kainic acid on nerve fibres and terminals in the cat spinal cord.

21 January 2018

1 reference

Neurotoxic effects of excitatory amino acids in the mouse spinal cord: quisqualate and kainate but not N-methyl-D-aspartate induce permanent neural damage

21 January 2018

1 reference

Glial cells potentiate kainate-induced neuronal death in a motoneuron-enriched spinal coculture system.

21 January 2018

1 reference

Different receptors mediate motor neuron death induced by short and long exposures to excitotoxicity

21 January 2018

1 reference

An alpha-mercaptoacrylic acid derivative (PD150606) inhibits selective motor neuron death via inhibition of kainate-induced Ca2+ influx and not via calpain inhibition

21 January 2018

1 reference

Neurological dysfunctions in mice expressing different levels of the Q/R site-unedited AMPAR subunit GluR-B.

21 January 2018

1 reference

Enhanced LTP in mice deficient in the AMPA receptor GluR2.

21 January 2018

1 reference

GluR2 deficiency accelerates motor neuron degeneration in a mouse model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

Calcium-permeable AMPA receptors promote misfolding of mutant SOD1 protein and development of amyotrophic lateral sclerosis in a transgenic mouse model

21 January 2018

1 reference

Glutamate receptors: RNA editing and death of motor neurons

21 January 2018

1 reference

The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis

21 January 2018

1 reference

Calbindin D-28k and parvalbumin in the rat nervous system

21 January 2018

1 reference

Endogenous calcium buffering in motoneurones of the nucleus hypoglossus from mouse

21 January 2018

1 reference

Calcium dynamics and buffering in motoneurones of the mouse spinal cord

21 January 2018

1 reference

Calcium dynamics and buffering in oculomotor neurones from mouse that are particularly resistant during amyotrophic lateral sclerosis (ALS)-related motoneurone disease

21 January 2018

1 reference

Protective effect of parvalbumin on excitotoxic motor neuron death.

21 January 2018

1 reference

Expression of metabotropic glutamate receptor mRNAs in the human spinal cord: implications for selective vulnerability of spinal motor neurons in amyotrophic lateral sclerosis

21 January 2018

1 reference

Immunohistochemical localization of group I and II metabotropic glutamate receptors in control and amyotrophic lateral sclerosis human spinal cord: upregulation in reactive astrocytes.

21 January 2018

1 reference

Differential expression of Group I metabotropic glutamate receptors in motoneurons at low and high risk for degeneration in ALS.

21 January 2018

1 reference

Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models

21 January 2018

1 reference

Effects of vascular endothelial growth factor (VEGF) on motor neuron degeneration

21 January 2018

1 reference

Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.

21 January 2018

1 reference

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

21 January 2018

1 reference

Minocycline prevents neurotoxicity induced by cerebrospinal fluid from patients with motor neurone disease

21 January 2018

1 reference

Minocycline delays disease onset and mortality in a transgenic model of ALS.

21 January 2018

1 reference

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

21 January 2018

1 reference

Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis

21 January 2018

1 reference

Neuroprotection by metabotropic glutamate receptor agonists on kainate-induced degeneration of motor neurons in spinal cord slices from adult rat

21 January 2018

1 reference

Excitotoxic Death of a Subset of Embryonic Rat Motor Neurons In Vitro

21 January 2018

1 reference