Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer (Q36499925)

14 August 2017

Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer (English)

1 reference

14 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26777065%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26777065%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26777065%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

David N Brown

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26777065%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Irene Caffa

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26777065%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Gabriella Cirmena

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26777065%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Daniela Piras

1 reference

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11 June 2020

Anna Garuti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26777065%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Maurizio Gallo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26777065%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Alessio Nencioni

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26777065%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

language of work or name

English

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publication date

18 January 2016

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14 August 2017

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11 June 2020

volume

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11 June 2020

page(s)

19435

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26777065%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

11 June 2020

start time

18 January 2016

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April 2022 Public Data File from Crossref

copyrighted

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describes a project that uses

1 reference

10 June 2022

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&rettype=xml&id=4726025

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4726025

inferred from PubMed Central ID database lookup

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30 September 2017

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Squalene monooxygenase - a target for hypercholesterolemic therapy

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GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

30 September 2017

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Cholesterol-Dependent Degradation of Squalene Monooxygenase, a Control Point in Cholesterol Synthesis beyond HMG-CoA Reductase

30 September 2017

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High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer

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An atlas of combinatorial transcriptional regulation in mouse and man

30 September 2017

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Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets

30 September 2017

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A high-resolution integrated analysis of genetic and expression profiles of breast cancer cell lines

30 September 2017

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

30 September 2017

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Squalene epoxidase, located on chromosome 8q24.1, is upregulated in 8q+ breast cancer and indicates poor clinical outcome in stage I and II disease

30 September 2017

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30 September 2017

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30 September 2017

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Molecular portraits of human breast tumours

30 September 2017

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30 September 2017

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Localization of the Squalene Epoxidase Gene (SQLE) to Human Chromosome Region 8q24.1

30 September 2017

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Allylamine derivatives: new class of synthetic antifungal agents inhibiting fungal squalene epoxidase

30 September 2017

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Isolation and characterization of c-myc, a cellular homolog of the oncogene (v-myc) of avian myelocytomatosis virus strain 29

30 September 2017

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Specific inhibition of fungal sterol biosynthesis by SF 86-327, a new allylamine antimycotic agent

30 September 2017

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Inhibition of squalene epoxidase by allylamine antimycotic compounds. A comparative study of the fungal and mammalian enzymes

30 September 2017

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Tellurium blocks cholesterol synthesis by inhibiting squalene metabolism: preferential vulnerability to this metabolic block leads to peripheral nervous system demyelination

30 September 2017

1 reference

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Cholesterol inhibition, cancer, and chemotherapy

30 September 2017

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Integrated profiling of basal and luminal breast cancers.

30 September 2017

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Differential inhibition of fungal amd mammalian squalene epoxidases by the benzylamine SDZ SBA 586 in comparison with the allylamine terbinafine

28 June 2018

1 reference

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(Aryloxy)methylsilane Derivatives as New Cholesterol Biosynthesis Inhibitors: Synthesis and Hypocholesterolemic Activity of a New Class of Squalene Epoxidase Inhibitors

28 June 2018

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Studies on Squalene Epoxidase of Rat Liver

28 June 2018

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NB-598: a potent competitive inhibitor of squalene epoxidase

28 June 2018

1 reference

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Regulation of squalene epoxidase in HepG2 cells

28 June 2018

1 reference

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Effect of a novel squalene epoxidase inhibitor, NB-598, on the regulation of cholesterol metabolism in Hep G2 cells

28 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4726025

Inhibition of cholesterol synthesis causes both hypercholesterolemia and hypocholesterolemia in hamsters

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4726025

Effect of FR194738, a potent inhibitor of squalene epoxidase, on cholesterol metabolism in HepG2 cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4726025

Terbinafine levels in serum, stratum corneum, dermis-epidermis (without stratum corneum), hair, sebum and eccrine sweat

21 September 2018

1 reference

12 December 2020

Hypolipidemic effects of NB-598 in dogs

1 reference

12 December 2020

Squalene-2,3-Oxide, an Intermediate in the Enzymatic Conversion of Squalene to Lanosterol and Cholesterol

1 reference

12 December 2020

High-resolution genomic and expression analyses of copy number alterations in breast tumors

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP19435

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26777065%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

11 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26777065%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

PubMed publication ID

26777065

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26777065%20AND%20SRC:MED&resulttype=core&format=json