The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety (Q36432425)

14 August 2017

The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety (English)

1 reference

14 August 2017

Khurshida Begum

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14 August 2017

Bert W O'Malley

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14 August 2017

Sang Jun Han

1 reference

14 August 2017

Charles E Foulds

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14 August 2017

Ross A Hamilton

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14 August 2017

Suzanna Bailey

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14 August 2017

Anna Malovannaya

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14 August 2017

Doug Chan

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14 August 2017

Jun Qin

1 reference

14 August 2017

20 October 2015

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14 August 2017

Molecular Pharmacology

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14 August 2017

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14 August 2017

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14 August 2017

14-26

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describes a project that uses

14 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4702103/fullTextXML

inferred from PubMed Central ID database lookup

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Bazedoxifene/conjugated estrogens for managing the burden of estrogen deficiency symptoms

30 September 2017

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Update on raloxifene: mechanism of action, clinical efficacy, adverse effects, and contraindications.

30 September 2017

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Proteomic analysis of coregulators bound to ERα on DNA and nucleosomes reveals coregulator dynamics

30 September 2017

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Cooperative activation of gene expression by agonists and antagonists mediated by estrogen receptor heteroligand dimer complexes

30 September 2017

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Breast density changes in a randomized controlled trial evaluating bazedoxifene/conjugated estrogens

30 September 2017

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Inhibitory effects of a bazedoxifene/conjugated equine estrogen combination on human breast cancer cells in vitro

30 September 2017

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The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice

30 September 2017

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Bazedoxifene: the evolving role of third-generation selective estrogen-receptor modulators in the management of postmenopausal osteoporosis

30 September 2017

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ERα phosphorylation at Y537 by Src triggers E6-AP-ERα binding, ERα ubiquitylation, promoter occupancy, and target gene expression.

30 September 2017

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Role of estrogen receptor signaling required for endometriosis-like lesion establishment in a mouse model

30 September 2017

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Estrogen receptors and human disease: an update

30 September 2017

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Endometrial cancer and venous thromboembolism in women under age 50 who take tamoxifen for prevention of breast cancer: a systematic review.

30 September 2017

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The selective estrogen receptor modulator bazedoxifene inhibits hormone-independent breast cancer cell growth and down-regulates estrogen receptor α and cyclin D1.

30 September 2017

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Treatment of osteoporosis and reduction in risk of invasive breast cancer in postmenopausal women with raloxifene

30 September 2017

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Tissue-Selective Agents: Selective Estrogen Receptor Modulators and the Tissue-Selective Estrogen Complex

30 September 2017

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Tissue-selective estrogen complexes: a promising option for the comprehensive management of menopausal symptoms

30 September 2017

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Endometrial safety: a key hurdle for selective estrogen receptor modulators in development

30 September 2017

1 reference

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Fbxo45, a novel ubiquitin ligase, regulates synaptic activity

30 September 2017

1 reference

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Gene expression profiling studies of three SERMs and their conjugated estrogen combinations in human breast cancer cells: insights into the unique antagonistic effects of bazedoxifene on conjugated estrogens

30 September 2017

1 reference

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The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73

30 September 2017

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Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development

30 September 2017

1 reference

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Impact of raloxifene or tamoxifen use on endometrial cancer risk: a population-based case-control study

30 September 2017

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Role of proteasomes in cellular regulation

30 September 2017

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Gene expression profiles in breast cancer to identify estrogen receptor target genes.

30 September 2017

1 reference

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Danazol for pelvic pain associated with endometriosis

30 September 2017

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Danazol for unexplained subfertility

30 September 2017

1 reference

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Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial

30 September 2017

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Ligand-induced estrogen receptor alpha degradation by the proteasome: new actors?

30 September 2017

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Estrogen receptors and human disease

30 September 2017

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E6AP and calmodulin reciprocally regulate estrogen receptor stability.

30 September 2017

1 reference

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The ubiquitin-proteasome system and cancer

30 September 2017

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Dynamic cell type specificity of SRC-1 coactivator in modulating uterine progesterone receptor function in mice

30 September 2017

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p73, the "assistant" guardian of the genome?

30 September 2017

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Use of estrogen antagonists and aromatase inhibitors in endometriosis.

30 September 2017

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Pharmacokinetics of selective estrogen receptor modulators

30 September 2017

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Influence of raloxifene on the efficacy of an estradiol-releasing ring for treating vaginal atrophy in postmenopausal women

30 September 2017

1 reference

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SERMs: current status and future trends

30 September 2017

1 reference

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Combinatorial control of gene expression by nuclear receptors and coregulators

30 September 2017

1 reference

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Gonadotropin-releasing hormone agonist treatment for endometriosis of the rectovaginal septum

30 September 2017

1 reference

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Selective oestrogen receptor modulation: molecular pharmacology for the millennium

30 September 2017

1 reference

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Proteasome-dependent degradation of the human estrogen receptor

30 September 2017

1 reference

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Long-term toxicity of tamoxifen

30 September 2017

1 reference

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Raloxifene (LY139481 HCI) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702103

Induction of endometriosis in mice: A new model sensitive to estrogen

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702103

Anti-oestrogen Therapy for Breast Cancer: A Trial of Tamoxifen at Two Dose Levels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702103

Long-term tamoxifen therapy to control or to prevent breast cancer: laboratory concept to clinical trials

30 September 2017

1 reference

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Tamoxifen (ICI 46,474) and the human carcinoma 8S oestrogen receptor

30 September 2017

1 reference

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Reduction of the intraperitoneal inflammation associated with endometriosis by treatment with medroxyprogesterone acetate

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702103

Placebo-controlled comparison of danazol and high-dose medroxyprogesterone acetate in the treatment of endometriosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702103

Molecular mechanisms of selective estrogen receptor modulator activity in human breast cancer cells: identification of novel nuclear cofactors of antiestrogen-ERα complexes by interaction proteomics

28 June 2018

1 reference

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Bazedoxifene/conjugated estrogens (BZA/CE): incidence of uterine bleeding in postmenopausal women

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702103

Endometrial effects of a tissue selective estrogen complex containing bazedoxifene/conjugated estrogens as a menopausal therapy.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702103

Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702103

Effect of raloxifene on the response to conjugated estrogen vaginal cream or nonhormonal moisturizers in postmenopausal vaginal atrophy

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702103

Danazol and medroxyprogesterone acetate inefficacious in the treatment of infertility in endometriosis

21 September 2018

1 reference

12 December 2020

The human estrogen receptor-alpha is a ubiquitinated protein whose stability is affected differentially by agonists, antagonists, and selective estrogen receptor modulators

1 reference

12 December 2020

The effects of gonadotrophin-releasing hormone agonists on iliac crest cancellous bone structure in women with endometriosis

1 reference

12 December 2020

1 reference

12 December 2020

Aromatase inhibition impairs skeletal modeling and decreases bone mineral density in growing male rats

1 reference

12 December 2020

Identifiers

DOI

10.1124/MOL.115.100925

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

26487511

1 reference