Pharmacokinetics of selective estrogen receptor modulators (Q34185019)

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English	Pharmacokinetics of selective estrogen receptor modulators	scientific article

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instance of

scholarly article

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stated in

Europe PubMed Central

PubMed publication ID

12648026

retrieved

31 July 2017

review article

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Europe PubMed Central

title

Pharmacokinetics of selective estrogen receptor modulators (English)

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Europe PubMed Central

PubMed publication ID

12648026

retrieved

31 July 2017

main subject

estrogen

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based on heuristic

inferred from title

pharmacokinetics

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based on heuristic

inferred from title

author name string

Karla C Morello

series ordinal

1

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Europe PubMed Central

PubMed publication ID

12648026

retrieved

31 July 2017

Gregory T Wurz

series ordinal

2

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stated in

Europe PubMed Central

PubMed publication ID

12648026

retrieved

31 July 2017

Michael W DeGregorio

series ordinal

3

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stated in

Europe PubMed Central

PubMed publication ID

12648026

retrieved

31 July 2017

publication date

1 January 2003

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stated in

Europe PubMed Central

PubMed publication ID

12648026

retrieved

31 July 2017

published in

Clinical Pharmacokinetics

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stated in

Europe PubMed Central

PubMed publication ID

12648026

retrieved

31 July 2017

volume

42

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stated in

Europe PubMed Central

PubMed publication ID

12648026

retrieved

31 July 2017

issue

4

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Europe PubMed Central

PubMed publication ID

12648026

retrieved

31 July 2017

page(s)

361-372

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Europe PubMed Central

PubMed publication ID

12648026

retrieved

31 July 2017

cites work

Age-related difference in tamoxifen disposition

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

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12 December 2020

based on heuristic

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Postmenopausal hormone therapy, SERMs, and coronary heart disease in women

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacology and clinical uses of tamoxifen

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolism of tamoxifen by human cytochromes P450 is rationalized by molecular modelling of the enzyme-substrate interactions: potential importance to its proposed anti-carcinogenic/carcinogenic actions

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of tamoxifen on the pharmacokinetics and endocrine effects of the aromatase inhibitor letrozole in postmenopausal women with breast cancer

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of bioavailability in man of tamoxifen after oral and rectal administration

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacology of tamoxifen and N-desmethyltamoxifen in patients with advanced breast cancer

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The bioavailability of Tamoplex (tamoxifen). Part 1. A pilot study

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biodistribution and scintigraphy of 11C-toremifene in rats bearing DMBA-induced mammary carcinoma

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LY353381.HCl: a novel raloxifene analog with improved SERM potency and efficacy in vivo

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and bioavailability of tamoxifen in postmenopausal healthy women

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective estrogenic effects of a novel triphenylethylene compound, FC1271a, on bone, cholesterol level, and reproductive tissues in intact and ovariectomized rats

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated plasma tamoxifen levels in a patient with liver obstruction

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of ospemifene (FC-1271a) on uterine endometrium, vaginal maturation index, and hormonal status in healthy postmenopausal women

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased serum concentrations of tamoxifen and its metabolites induced by aminoglutethimide

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

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12 December 2020

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A phase III comparison of two toremifene doses to tamoxifen in postmenopausal women with advanced breast cancer. Eastern European Study Group

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divergent effects of raloxifene HCI on the pharmacokinetics and pharmacodynamics of warfarin

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of age on toremifene pharmacokinetics

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase III trials of toremifene vs tamoxifen.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen in the treatment of breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and bioavailability of tamoxifen in healthy volunteers

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of effects of tamoxifen and toremifene on bone biochemistry and bone mineral density in postmenopausal breast cancer patients

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of toremifene to human serum proteins

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adjuvant trials of toremifene vs tamoxifen: the European experience.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P-450 3A and 2D6 catalyze ortho hydroxylation of 4-hydroxytamoxifen and 3-hydroxytamoxifen (droloxifene) yielding tamoxifen catechol: involvement of catechols in covalent binding to hepatic proteins.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of the novel antiestrogenic agent toremifene in subjects with altered liver and kidney function.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacology of tamoxifen in patients with breast cancer: comparison of traditional and loading dose schedules

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toremifene. A review of its pharmacological properties and clinical efficacy in the management of advanced breast cancer

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raloxifene: A selective estrogen receptor modulator (SERM) with multiple target system effects

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of impaired renal function on tamoxifen

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of raloxifene on serum lipids and coagulation factors in healthy postmenopausal women

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and pharmacological effects of toremifene metabolites

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of (deaminohydroxy)toremifene in humans: a new, selective estrogen-receptor modulator

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of low dose tamoxifen on the insulin-like growth factor system in healthy women

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of cytochrome P450 3A enzyme family in the major metabolic pathways of toremifene in human liver microsomes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolism of tamoxifen (I.C.I. 46,474). II. In female patients

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen and toremifene concentrations in plasma are greatly decreased by rifampin

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the metabolism and pharmacokinetics of tamoxifen in normal volunteers

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of toremifene

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of postmenopausal women with osteoporosis or low bone density with raloxifene. Raloxifene Study Group.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I study of a third-generation selective estrogen receptor modulator, LY353381.HCL, in metastatic breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I clinical and pharmacokinetics study of high-dose toremifene in postmenopausal patients with advanced breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of tamoxifen plus letrozole with assessment of pharmacokinetic interaction in postmenopausal women with metastatic breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The selective uptake of tamoxifen by human uterine tissue

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Life threatening interaction between tamoxifen and warfarin.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of endocrine agents used in advanced breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raloxifene: a selective estrogen receptor modulator.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of tamoxifen and its N-desmethyl and 4-hydroxy metabolites on rat liver microsomal enzymes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen and toremifene in breast cancer: comparison of safety and efficacy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of toremifene and its metabolites in patients with advanced breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of drugs used in the treatment of breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen metabolic patterns within a glioma patient population treated with high-dose tamoxifen

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic use.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of 4-hydroxy-N-desmethyltamoxifen and other tamoxifen metabolites in human biological fluids during tamoxifen treatment

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Raloxifene on Bone Mineral Density, Serum Cholesterol Concentrations, and Uterine Endometrium in Postmenopausal Women

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiatherogenic effects of adjuvant antiestrogens: a randomized trial comparing the effects of tamoxifen and toremifene on plasma lipid levels in postmenopausal women with node-positive breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distribution and metabolism of 14C-labelled tamoxifen in spayed female mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of toremifene

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raloxifene hydrochloride

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of raloxifene and its clinical application

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I study of the tolerance and pharmacokinetics of toremifene in patients with cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The bioavailability of Tamoplex (tamoxifen). Part 2. A single dose cross-over study in healthy male volunteers

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of cross-resistance of the selective estrogen receptor modulators arzoxifene (LY353381) and LY117018 in tamoxifen-stimulated breast cancer xenografts.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen and metabolites in MCF7 cells: correlation between binding to estrogen receptor and inhibition of cell growth.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and biological activity of tamoxifen metabolites in human serum

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of tamoxifen and its metabolites in rat and human tissues during steady-state treatment.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12648026

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.2165/00003088-200342040-00004

1 reference

stated in

Europe PubMed Central

PubMed publication ID

12648026

retrieved

31 July 2017

Dimensions Publication ID

1052002165

0 references

PubMed publication ID

12648026

1 reference

stated in

Europe PubMed Central

PubMed publication ID

12648026

retrieved

31 July 2017

 

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