Age-related changes in CD8 T cell homeostasis and immunity to infection (Q36345382)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22554418%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Age-related changes in CD8 T cell homeostasis and immunity to infection (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22554418%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

author

Janko Nikolich-Žugich

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22554418%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22554418%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22554418%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Kristin R Renkema

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22554418%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Gang Li

1 reference

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31 January 2020

publication date

1 May 2012

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31 January 2020

published in

Seminars in Immunology

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31 January 2020

volume

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31 January 2020

issue

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31 January 2020

page(s)

356-364

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22554418%20AND%20SRC:MED&resulttype=core&format=json

Age-associated alterations in CD8α+ dendritic cells impair CD8 T-cell expansion in response to an intracellular bacterium

31 January 2020

cites work

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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CD8α(+) dendritic cells are an obligate cellular entry point for productive infection by Listeria monocytogenes

30 September 2017

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Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions

30 September 2017

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CD8+ T cell differentiation in the aging immune system: until the last clone standing

30 September 2017

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The narrowing of the CD8 T cell repertoire in old age

30 September 2017

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Increased apoptosis, curtailed expansion and incomplete differentiation of CD8+ T cells combine to decrease clearance of L. monocytogenes in old mice

30 September 2017

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Dynamic imaging of the effector immune response to listeria infection in vivo

30 September 2017

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Impaired Interferon Signaling in Dendritic Cells From Older Donors Infected In Vitro With West Nile Virus

30 September 2017

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Keratinocytes Are Cell Targets of West Nile Virus In Vivo

30 September 2017

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Repeated in vivo stimulation of T and B cell responses in old mice generates protective immunity against lethal West Nile virus encephalitis

30 September 2017

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Evolution of the antigen-specific CD8+ TCR repertoire across the life span: evidence for clonal homogenization of the old TCR repertoire

30 September 2017

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West nile virus RNA not detected in urine of 40 people tested 6 years after acute West Nile virus disease

30 September 2017

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Impact of age on T cell signaling: a general defect or specific alterations?

30 September 2017

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Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF

30 September 2017

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The innate immune adaptor molecule MyD88 restricts West Nile virus replication and spread in neurons of the central nervous system

30 September 2017

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Role of CMV in immune senescence

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Cell-intrinsic defects in the proliferative response of antiviral memory CD8 T cells in aged mice upon secondary infection

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Inflation and long-term maintenance of CD8 T cells responding to a latent herpesvirus depend upon establishment of latency and presence of viral antigens

30 September 2017

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Persistent Infection with West Nile Virus Years after Initial Infection

30 September 2017

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Key role of T cell defects in age-related vulnerability to West Nile virus

30 September 2017

1 reference

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Evidence of premature immune aging in patients thymectomized during early childhood

30 September 2017

1 reference

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Limited expansion of virus-specific CD8 T cells in the aged environment.

30 September 2017

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Suppression of cell-mediated immunity following recognition of phagosome-confined bacteria

30 September 2017

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Redefining chronic viral infection

30 September 2017

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Effector T-cell differentiation during viral and bacterial infections: Role of direct IL-12 signals for cell fate decision of CD8(+) T cells

30 September 2017

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IL-23 promotes the production of IL-17 by antigen-specific CD8 T cells in the absence of IL-12 and type-I interferons.

30 September 2017

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Identification of an IFN-gamma-producing neutrophil early in the response to Listeria monocytogenes

30 September 2017

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Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity

30 September 2017

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The antigen-specific CD8+ T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion

30 September 2017

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Foci of Listeria monocytogenes persist in the bone marrow

30 September 2017

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Clonal expansions and loss of receptor diversity in the naive CD8 T cell repertoire of aged mice

30 September 2017

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West Nile virus-specific CD4 T cells exhibit direct antiviral cytokine secretion and cytotoxicity and are sufficient for antiviral protection

30 September 2017

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Aging mice exhibit a functional defect in mucosal dendritic cell response against an intracellular pathogen

30 September 2017

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Aging impairs IFN regulatory factor 7 up-regulation in plasmacytoid dendritic cells during TLR9 activation

30 September 2017

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Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection

30 September 2017

1 reference

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Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections

30 September 2017

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Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus

30 September 2017

1 reference

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Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates

30 September 2017

1 reference

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Unique functions of splenic CD8alpha+ dendritic cells during infection with intracellular pathogens

30 September 2017

1 reference

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Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude.

30 September 2017

1 reference

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Tissue tropism and neuroinvasion of West Nile virus do not differ for two mouse strains with different survival rates

30 September 2017

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Protective capacity and epitope specificity of CD8(+) T cells responding to lethal West Nile virus infection

30 September 2017

1 reference

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IL-12 and type-I IFN synergize for IFN-gamma production by CD4 T cells, whereas neither are required for IFN-gamma production by CD8 T cells after Listeria monocytogenes infection

30 September 2017

1 reference

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Importance of vertical and horizontal transmission of West Nile virus by Culex pipiens in the Northeastern United States.

30 September 2017

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HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

30 September 2017

1 reference

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Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly

30 September 2017

1 reference

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Restoring function in exhausted CD8 T cells during chronic viral infection

30 September 2017

1 reference

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Antibody response to influenza vaccination in the elderly: a quantitative review

30 September 2017

1 reference

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Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

30 September 2017

1 reference

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Virology, pathology, and clinical manifestations of West Nile virus disease

30 September 2017

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Vaccines for women age 50 and older

30 September 2017

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30 September 2017

1 reference

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The many important facets of T-cell repertoire diversity

30 September 2017

1 reference

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Infectious disease risk in the elderly

30 September 2017

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Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection

30 September 2017

1 reference

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Old mice express a transient early resistance to pulmonary tuberculosis that is mediated by CD8 T cells

30 September 2017

1 reference

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Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells

30 September 2017

1 reference

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IL-7 is critical for homeostatic proliferation and survival of naive T cells

30 September 2017

1 reference

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The outbreak of West Nile virus infection in the New York City area in 1999

30 September 2017

1 reference

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Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Control of murine cytomegalovirus in the lungs: relative but not absolute immunodominance of the immediate-early 1 nonapeptide during the antiviral cytolytic T-lymphocyte response in pulmonary infiltrates

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

The effect of aging on susceptibility to infection.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Limitations in plasticity of the T-cell receptor repertoire

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Distinct responses of splenic dendritic cell subsets to infection with Listeria monocytogenes: maturation phenotype, level of infection, and T cell priming capacity ex vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

29 June 2018

1 reference

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The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

29 June 2018

1 reference

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Premature age-related comorbidities among HIV-infected persons compared with the general population

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Infection with cytomegalovirus but not herpes simplex virus induces the accumulation of late-differentiated CD4+ and CD8+ T-cells in humans

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Splenic CD8α⁺ dendritic cells undergo rapid programming by cytosolic bacteria and inflammation to induce protective CD8⁺ T-cell memory

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Hallmark features of immunosenescence are absent in familial longevity

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Resident and monocyte-derived dendritic cells become dominant IL-12 producers under different conditions and signaling pathways

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Ex vivo enzymatic treatment of aged CD4 T cells restores antigen-driven CD69 expression and proliferation in mice

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4+ T cells during aging

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Revving the engine: signal transduction fuels T cell activation

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Aging affects initiation and continuation of T cell proliferation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Early acquisition of cytolytic function and transcriptional changes in a primary CD8+ T-cell response in vivo.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Extracellular replication of Listeria monocytogenes in the murine gall bladder

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Duration of antiviral immunity after smallpox vaccination

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Memory inflation: continuous accumulation of antiviral CD8+ T cells over time.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

A specific role for B cells in the generation of CD8 T cell memory by recombinant Listeria monocytogenes.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Defective generation but normal maintenance of memory T cells in old mice.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Age-associated decrease in virus-specific CD8+ T lymphocytes during primary influenza infection

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

Diminished T-cell response to influenza virus in aged mice.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480557

22 September 2018

1 reference

12 December 2020

Murine [corrected] myeloid dendritic cell-dependent toll-like receptor immunity is preserved with aging

1 reference

12 December 2020

Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes-infected IFN-gamma receptor-deficient mice

1 reference

12 December 2020

Trends in influenza and pneumonia among older persons in the United States

1 reference

12 December 2020

Cutting Edge: Protective Cell-Mediated Immunity to Listeria monocytogenes in the Absence of Myeloid Differentiation Factor 88

1 reference

12 December 2020

Specific immunity to Listeria monocytogenes in the absence of IFN gamma

1 reference

12 December 2020

Separation of T helper 1 clone cytolysis from proliferation and lymphokine production using analog peptides

1 reference

12 December 2020

CD8alpha+ dendritic cells are required for efficient entry of Listeria monocytogenes into the spleen

1 reference

12 December 2020

Morphologically and functionally intact dendritic cells can be derived from the peripheral blood of aged individuals

1 reference

12 December 2020

Functional consequences of a T cell receptor D beta 2 and J beta 2 gene segment deletion

1 reference

12 December 2020

Enhancement of CD8 T-cell function through modifying surface glycoproteins in young and old mice

1 reference

12 December 2020

Cytokine production after influenza vaccination in a healthy elderly population

1 reference

12 December 2020

Cytosolic expression of SecA2 is a prerequisite for long-term protective immunity

1 reference

12 December 2020

Unimpaired dendritic cells can be derived from monocytes in old age and can mobilize residual function in senescent T cells

1 reference

12 December 2020

A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3

1 reference

12 December 2020

T cell responses are better correlates of vaccine protection in the elderly

1 reference

12 December 2020

10.1016/J.SMIM.2012.04.009

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22554418%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22554418%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PubMed publication ID

22554418

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22554418%20AND%20SRC:MED&resulttype=core&format=json