Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus (Q27469800)

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F Lechner

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M C Jung

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H Diepolder

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T Gerlach

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G Lauer

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B Walker

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J Sullivan

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R Phillips

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G R Pape

Why do cytotoxic T lymphocytes fail to eliminate hepatitis C virus? Lessons from studies using major histocompatibility complex class I peptide tetramers

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language of work or name

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June 2001

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5550-8

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21 March 2017

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Quantitative analysis of hepatitis C virus-specific CD8(+) T cells in peripheral blood and liver using peptide-MHC tetramers

21 March 2017

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Viral immune evasion due to persistence of activated T cells without effector function

21 March 2017

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Compartmentalization of T lymphocytes to the site of disease: intrahepatic CD4+ T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C

21 March 2017

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HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release

21 March 2017

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Analysis of successful immune responses in persons infected with hepatitis C virus

21 March 2017

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Phenotypic analysis of antigen-specific T lymphocytes

21 March 2017

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Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C

21 March 2017

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The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies

7 April 2017

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Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C

7 April 2017

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Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response

7 April 2017

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Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection

7 April 2017

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Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors.

7 April 2017

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HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

29 September 2017

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Viral persistence in vivo through selection of neutralizing antibody-escape variants.

29 September 2017

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Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes.

29 September 2017

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A critical role for neutralizing-antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: implications for adoptive immunotherapy of virus carriers

29 September 2017

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Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection

29 September 2017

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Cytotoxic T lymphocyte response to hepatitis C virus-derived peptides containing the HLA A2.1 binding motif

29 September 2017

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Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

29 September 2017

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Low stimulatory capacity of lymphoid dendritic cells expressing hepatitis C virus genes

2 June 2018

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Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus In vivo

2 June 2018

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Rapid effector function in CD8+ memory T cells

2 June 2018

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Viral escape and the failure of cellular immune responses

2 June 2018

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CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained

27 November 2018

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Hepatitis C virus-specific T-cell reactivity during interferon and ribavirin treatment in chronic hepatitis C.

27 November 2018

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Specificity of CTL interactions with peptide-MHC class I tetrameric complexes is temperature dependent

27 November 2018

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Hepatitis C virus-specific CD4(+) T cells: do they help or damage?

27 November 2018

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Association of multispecific CD4(+) response to hepatitis C and severity of recurrence after liver transplantation

27 November 2018

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Liver-derived CTL in hepatitis C virus infection: breadth and specificity of responses in a cohort of persons with chronic infection.

27 November 2018

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Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

27 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/11356962

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Distribution fate and mechanism of immune modulation following mucosal delivery of plasmid DNA encoding IL-10

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https://pubmed.ncbi.nlm.nih.gov/11356962