Coagulation factor V mediates inhibition of tissue factor signaling by activated protein C in mice (Q36301525)

13 August 2017

Coagulation factor V mediates inhibition of tissue factor signaling by activated protein C in mice (English)

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13 August 2017

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Hai Po H Liang

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26341257%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Edward J Kerschen

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1 June 2020

Sreemanti Basu

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1 June 2020

Irene Hernandez

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1 June 2020

Mark Zogg

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1 June 2020

Shuang Jia

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1 June 2020

Martin J Hessner

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1 June 2020

Raffaella Toso

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1 June 2020

Alireza R Rezaie

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1 June 2020

José A Fernández

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1 June 2020

Rodney M Camire

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1 June 2020

Hartmut Weiler

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1 June 2020

language of work or name

English

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publication date

4 September 2015

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13 August 2017

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1 June 2020

volume

126

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1 June 2020

issue

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1 June 2020

page(s)

2415-2423

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EPCR-dependent PAR2 activation by the blood coagulation initiation complex regulates LPS-triggered interferon responses in mice.

1 June 2020

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30 September 2017

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The endothelial protein C receptor supports tissue factor ternary coagulation initiation complex signaling through protease-activated receptors.

30 September 2017

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30 September 2017

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Zn²(+) -containing protein S inhibits extrinsic factor X-activating complex independently of tissue factor pathway inhibitor

30 September 2017

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The efficacy of activated protein C in murine endotoxemia is dependent on integrin CD11b

30 September 2017

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Engineering of substrate selectivity for tissue factor.factor VIIa complex signaling through protease-activated receptor 2.

30 September 2017

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APC resistance: biological basis and acquired influences

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Factor V Leiden and hemophilia

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Extracellular histones are major mediators of death in sepsis

30 September 2017

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The molecular basis of factor V and VIII procofactor activation

30 September 2017

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Recombinant human activated protein C inhibits integrin-mediated neutrophil migration

30 September 2017

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Hyperantithrombotic, noncytoprotective Glu149Ala-activated protein C mutant

30 September 2017

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Dissociation of activated protein C functions by elimination of protein S cofactor enhancement

30 September 2017

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Functional properties and active-site topographies of factor X Gla- and prothrombin Gla-domain chimeras of activated protein C

30 September 2017

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Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C.

30 September 2017

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Active and exo-site inhibition of human factor Xa: structure of des-Gla factor Xa inhibited by NAP5, a potent nematode anticoagulant protein from Ancylostoma caninum

30 September 2017

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Engineering a disulfide bond to stabilize the calcium-binding loop of activated protein C eliminates its anticoagulant but not its protective signaling properties

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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The C-terminal region of the factor V B-domain is crucial for the anticoagulant activity of factor V.

30 September 2017

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Nonenzymatic anticoagulant activity of the mutant serine protease Ser360Ala-activated protein C mediated by factor Va

30 September 2017

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Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages.

30 September 2017

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P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice

29 June 2018

1 reference

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Multifunctional specificity of the protein C/activated protein C Gla domain.

29 June 2018

1 reference

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Activated protein C resistance: molecular mechanisms based on studies using purified Gln506-factor V.

29 June 2018

1 reference

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Novel FV mutation (W1920R, FVNara) associated with serious deep vein thrombosis and more potent APC resistance relative to FVLeiden.

29 June 2018

1 reference

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Role of coagulation FVIII in septic peritonitis assessed in hemophilic mice

22 September 2018

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Impaired hemostasis and protection against thrombosis in protease-activated receptor 4-deficient mice is due to lack of thrombin signaling in platelets

22 September 2018

1 reference

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Activated protein C variants with normal cytoprotective but reduced anticoagulant activity

22 September 2018

1 reference

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Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain

22 September 2018

1 reference

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Impaired APC cofactor activity of factor V plays a major role in the APC resistance associated with the factor V Leiden (R506Q) and R2 (H1299R) mutations

22 September 2018

1 reference

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Factor Va is inactivated by activated protein C in the absence of cleavage sites at Arg-306, Arg-506, and Arg-679.

22 September 2018

1 reference

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Unique in vivo modifications of coagulation factor V produce a physically and functionally distinct platelet-derived cofactor: characterization of purified platelet-derived factor V/Va

22 September 2018

1 reference

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Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia.

22 September 2018

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Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A

22 September 2018

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Spontaneous thrombosis in mice carrying the factor V Leiden mutation

22 September 2018

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12 December 2020

Functional characterization of factor V-Ile359Thr: a novel mutation associated with thrombosis

1 reference

12 December 2020

Characterization of two forms of human factor Va with different cofactor activities

1 reference

12 December 2020

Human factor Va1 and factor Va2: properties in the procoagulant and anticoagulant pathways

1 reference

12 December 2020

Inhibitory sequences within the B-domain stabilize circulating factor V in an inactive state

1 reference

12 December 2020

Activated protein C modulates inflammation, apoptosis and tissue factor procoagulant activity by regulating endoplasmic reticulum calcium depletion in blood monocytes

1 reference

12 December 2020

The anticoagulant function of coagulation factor V

1 reference

12 December 2020

10.1182/BLOOD-2015-05-644401

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26341257%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

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1 June 2020

PubMed publication ID

26341257

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26341257%20AND%20SRC:MED&resulttype=core&format=json