One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A. (Q35904895)

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scientific article published on 26 January 2016

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English	One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A.	scientific article published on 26 January 2016

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scholarly article

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Europe PubMed Central

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11 August 2017

One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A. (English)

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11 August 2017

toll-like receptor

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Staphylococcus aureus

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based on heuristic

inferred from title

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Rino Rappuoli

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11 August 2017

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Guido Grandi

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Maria Rita Fontana

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Maria Rita Fontana

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Sandra Nuti

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Francesca Mancini

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Elisabetta Monaci

2

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Giuseppe Lofano

3

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Antonina Torre

4

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Marta Bacconi

5

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Simona Tavarini

6

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Chiara Sammicheli

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Letizia Arcidiacono

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Bruno Galletti

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Donatello Laera

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Michele Pallaoro

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Giovanna Tuscano

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Giuliano Bensi

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Silvia Rossi-Paccani

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Ennio De Gregorio

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Fabio Bagnoli

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Elisabetta Soldaini

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Sylvie Bertholet

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26 January 2016

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1

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e0147767

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11 August 2017

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Creative Commons Attribution 4.0 International

26 January 2016

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April 2022 Public Data File from Crossref

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0 references

Phagocyte subsets and lymphocyte clonal deletion behind ineffective immune response to Staphylococcus aureus

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27 July 2018

Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus

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The 3 major types of innate and adaptive cell-mediated effector immunity

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27 July 2018

Efficacy profile of a bivalent Staphylococcus aureus glycoconjugated vaccine in adults on hemodialysis: Phase III randomized study

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Rational design of small molecules as vaccine adjuvants.

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27 July 2018

Recombinant ESAT-6-like proteins provoke protective immune responses against invasive Staphylococcus aureus disease in a murine model

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27 July 2018

Neutrophil-Mediated Phagocytosis of Staphylococcus aureus

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The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing

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Unleashing the potential of NOD- and Toll-like agonists as vaccine adjuvants

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Staphylococcal Esx proteins modulate apoptosis and release of intracellular Staphylococcus aureus during infection in epithelial cells.

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Key roles of adjuvants in modern vaccines

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Primary immunodeficiencies underlying fungal infections

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27 July 2018

Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus

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27 July 2018

Staphylococcus aureus α-toxin: nearly a century of intrigue

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The use of Toll-like receptor 7/8 agonists as vaccine adjuvants

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27 July 2018

Structural and functional characterization of the Staphylococcus aureus virulence factor and vaccine candidate FhuD2

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27 July 2018

Immunity to infection in IL-17-deficient mice and humans

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27 July 2018

Abscess formation and alpha-hemolysin induced toxicity in a mouse model of Staphylococcus aureus peritoneal infection.

1 reference

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27 July 2018

Epidemiology and outcome of major postoperative infections following cardiac surgery: risk factors and impact of pathogen type

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27 July 2018

Predictors of mortality in Staphylococcus aureus Bacteremia

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27 July 2018

Challenges for a universal Staphylococcus aureus vaccine

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27 July 2018

Immunization with Staphylococcus aureus iron regulated surface determinant B (IsdB) confers protection via Th17/IL17 pathway in a murine sepsis model

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27 July 2018

Targeting of alpha-hemolysin by active or passive immunization decreases severity of USA300 skin infection in a mouse model

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27 July 2018

Role of interleukin-17A in cell-mediated protection against Staphylococcus aureus infection in mice immunized with the fibrinogen-binding domain of clumping factor A.

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27 July 2018

IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice

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27 July 2018

IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge

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27 July 2018

Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice

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27 July 2018

Genetic requirements for Staphylococcus aureus abscess formation and persistence in host tissues

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Immunological mechanisms underlying the genetic predisposition to severe Staphylococcus aureus infection in the mouse model

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27 July 2018

Identification and characterization of fhuD1 and fhuD2, two genes involved in iron-hydroxamate uptake in Staphylococcus aureus.

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Innate Immunity: The Virtues of a Nonclonal System of Recognition

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Site-directed mutagenesis of the alpha-toxin gene of Staphylococcus aureus: role of histidines in toxin activity in vitro and in a murine model

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Autophagy mediates tolerance to Staphylococcus aureus alpha-toxin.

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Staphylococcus aureus infection of mice expands a population of memory γδ T cells that are protective against subsequent infection.

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Staphylococcus aureus FhuD2 is involved in the early phase of staphylococcal dissemination and generates protective immunity in mice.

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10.1371/JOURNAL.PONE.0147767

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Europe PubMed Central

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11 August 2017

2016PLoSO..1147767M

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24 November 2022

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PMC publication ID

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11 August 2017

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11 August 2017

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