TRAIL and malignant glioma. (Q35756919)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110189%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

review article

1 reference

title

TRAIL and malignant glioma (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110189%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110189%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Christine J Hawkins

1 reference

10 August 2017

publication date

1 January 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110189%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

published in

Vitamins and Hormones

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110189%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

volume

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110189%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

page(s)

427-452

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110189%20AND%20SRC:MED&resulttype=core&format=json

A mechanism of resistance to TRAIL/Apo2L-induced apoptosis of newly established glioma cell line and sensitisation to TRAIL by genotoxic agents

27 December 2019

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7 January 2021

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7 January 2021

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

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7 January 2021

Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kappaB activation and cFLIP(L) up-regulation

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7 January 2021

Growth and chemotherapeutic response in athymic mice of tumors arising from human glioma-derived cell lines.

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7 January 2021

Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificity

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7 January 2021

Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway

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7 January 2021

Chemotherapy for the treatment of oligodendroglial tumors

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7 January 2021

PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis

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7 January 2021

The differential sensitivity of Bc1-2-overexpressing human breast tumor cells to TRAIL or doxorubicin-induced apoptosis is dependent on Bc1-2 protein levels.

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7 January 2021

The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

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7 January 2021

TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

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7 January 2021

Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials

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7 January 2021

A rapid and systematic review of the effectiveness of temozolomide for the treatment of recurrent malignant glioma

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7 January 2021

Lack of tumor necrosis factor-related apoptosis-inducing ligand but presence of its receptors in the human brain

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7 January 2021

Induction of TRAIL-mediated glioma cell death by human T cells.

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7 January 2021

TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB.

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7 January 2021

Many cuts to ruin: a comprehensive update of caspase substrates

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7 January 2021

Expression of TRAIL and its receptors in human brain tumors

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7 January 2021

Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.

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7 January 2021

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo

1 reference

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7 January 2021

Fas-associated Death Domain Protein and Caspase-8 Are Not Recruited to the Tumor Necrosis Factor Receptor 1 Signaling Complex during Tumor Necrosis Factor-induced Apoptosis

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7 January 2021

The biochemistry of apoptosis

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7 January 2021

Erythroid differentiation sensitizes K562 leukemia cells to TRAIL-induced apoptosis by downregulation of c-FLIP.

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7 January 2021

Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis

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7 January 2021

A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

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7 January 2021

Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways

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7 January 2021

Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L)

1 reference

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7 January 2021

A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL

1 reference

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7 January 2021

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967022-1

7 January 2021

TRAIL-R2 (DR5) mediates apoptosis of synovial fibroblasts in rheumatoid arthritis

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7 January 2021

Death and anti-death: tumour resistance to apoptosis

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7 January 2021

Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines

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7 January 2021

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

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7 January 2021

An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis

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7 January 2021

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

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7 January 2021

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

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7 January 2021

Caspase-8 levels affect necessity for mitochondrial amplification in death ligand-induced glioma cell apoptosis

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7 January 2021

Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells.

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7 January 2021

Bcl–2 protects from lethal hepatic apoptosis induced by an ant–Fas antibody in mice

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7 January 2021

Radiotherapy for newly diagnosed malignant glioma in adults: a systematic review

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7 January 2021

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

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7 January 2021

Antitumor activity and prolonged expression from a TRAIL-expressing adenoviral vector

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7 January 2021

Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation

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7 January 2021

The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase

1 reference

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7 January 2021

A Bcl-2 transgene expressed in hepatocytes does not protect mice from fulminant liver destruction induced by Fas ligand

1 reference

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7 January 2021

Activation-induced cell death: the controversial role of Fas and Fas ligand in immune privilege and tumour counterattack

1 reference

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7 January 2021

Involvement of APO2 ligand/TRAIL in activation-induced death of Jurkat and human peripheral blood T cells

1 reference

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7 January 2021

p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma

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7 January 2021

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

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7 January 2021

Molecular analysis of glioblastoma: pathway profiling and its implications for patient therapy

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7 January 2021

A GTP-binding adapter protein couples TRAIL receptors to apoptosis-inducing proteins

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7 January 2021

Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation

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7 January 2021

TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967022-1

7 January 2021

The tumor necrosis factor-related apoptosis-inducing ligand receptors TRAIL-R1 and TRAIL-R2 have distinct cross-linking requirements for initiation of apoptosis and are non-redundant in JNK activation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967022-1

7 January 2021

TRAIL (APO-2L) induces apoptosis in human prostate cancer cells that is inhibitable by Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967022-1

7 January 2021

APO2L/TRAIL expression in human brain tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967022-1

7 January 2021

Adenoviral (full-length) Apo2L/TRAIL gene transfer is an ineffective treatment strategy for malignant glioma

1 reference

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7 January 2021

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) triggers apoptosis in normal prostate epithelial cells

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7 January 2021

Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)

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7 January 2021

From rodent glial precursor cell to human glial neoplasia in the oligodendrocyte-type-2 astrocyte lineage

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7 January 2021

Growth factors, glia and gliomas

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7 January 2021

Synergistic induction of tumor cell apoptosis by death receptor antibody and chemotherapy agent through JNK/p38 and mitochondrial death pathway

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7 January 2021

Dose escalation of carmustine in surgically implanted polymers in patients with recurrent malignant glioma: a New Approaches to Brain Tumor Therapy CNS Consortium trial

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7 January 2021

Systemic metastasis in glioblastoma may represent the emergence of neoplastic subclones

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7 January 2021

What is an apoptotic index measuring? A commentary

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7 January 2021

Molecular pathogenesis of malignant gliomas

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7 January 2021

Neural stem cells and neuro-oncology: quo vadis?

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7 January 2021

Dysregulation of apoptosis in cancer

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7 January 2021

Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines

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7 January 2021

APO2 ligand: a novel lethal weapon against malignant glioma?

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7 January 2021

Human astrocytic brain tumors express AP02L/TRAIL.

1 reference

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7 January 2021

A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection

1 reference

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7 January 2021

CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release

1 reference

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7 January 2021

Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity.

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7 January 2021

Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells

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7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

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7 January 2021

TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB

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7 January 2021

Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity

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7 January 2021

Tumorigenic cell culture lines from a spontaneous VM/Dk murine astrocytoma (SMA).

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7 January 2021

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

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7 January 2021

A protective role of PKCepsilon against TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in glioma cells

1 reference

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7 January 2021

Tumor necrosis factor-related apoptosis-inducing ligand in T cell development: sensitivity of human thymocytes

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7 January 2021

Nature's TRAIL--on a path to cancer immunotherapy

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7 January 2021

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

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7 January 2021

Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

1 reference

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7 January 2021

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

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7 January 2021

Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials

1 reference

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7 January 2021

Overexpression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells

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7 January 2021

Aggressive childhood neuroblastomas do not express caspase-8: an important component of programmed cell death

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7 January 2021

Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptor

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7 January 2021

Involvement of the bcl-2 gene in human follicular lymphoma

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7 January 2021

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

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7 January 2021

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

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7 January 2021

Expression of TRAIL receptors in human autoreactive and foreign antigen-specific T cells.

1 reference

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7 January 2021

TRAIL receptor and CD95 signal to mitochondria via FADD, caspase-8/10, Bid, and Bax but differentially regulate events downstream from truncated Bid

1 reference

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7 January 2021

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

1 reference

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7 January 2021

Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967022-1

7 January 2021

Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967022-1

7 January 2021

Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967022-1

7 January 2021

Preclinical studies with IL-13PE38QQR for therapy of malignant glioma.

1 reference

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7 January 2021

10.1016/S0083-6729(04)67022-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110189%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110189%20AND%20SRC:MED&resulttype=core&format=json