Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. (Q40789234)

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English	Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.	scientific article

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scholarly article

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

title

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity (English)

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

main subject

cytotoxicity

0 references

antibody

1 reference

based on heuristic

inferred from title

author

Robert P. Kimberly

series ordinal

10

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

author name string

Ichikawa K

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

Liu W

series ordinal

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

Zhao L

series ordinal

3

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

Wang Z

series ordinal

4

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

Liu D

series ordinal

5

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

Ohtsuka T

series ordinal

6

1 reference

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Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

Zhang H

series ordinal

7

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stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

Mountz JD

series ordinal

8

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

Koopman WJ

series ordinal

9

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

Zhou T

series ordinal

11

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

language of work or name

English

0 references

publication date

1 August 2001

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

published in

Nature Medicine

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

volume

7

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

issue

8

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

page(s)

954-960

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

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Death Receptor 5, a New Member of the TNFR Family, and DR4 Induce FADD-Dependent Apoptosis and Activate the NF-κB Pathway

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7 January 2021

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TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB

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An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL

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Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family

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The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

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TRAIL causes cleavage of bid by caspase-8 and loss of mitochondrial membrane potential resulting in apoptosis in BJAB cells

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TRAIL receptor-2 signals apoptosis through FADD and caspase-8

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FADD is required for DR4- and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts

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FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

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TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways

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Identifiers

DOI

10.1038/91000

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

PubMed publication ID

11479629

1 reference

stated in

Europe PubMed Central

PubMed publication ID

11479629

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11479629%20AND%20SRC:MED&resulttype=core&format=json

retrieved

9 November 2019

 

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