Caveolins, caveolae, and lipid rafts in cellular transport, signaling, and disease (Q35723460)

9 August 2017

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title

Caveolins, caveolae, and lipid rafts in cellular transport, signaling, and disease (English)

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9 August 2017

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Andrew F G Quest

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9 August 2017

Lisette Leyton

series ordinal

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9 August 2017

Mario Párraga

series ordinal

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9 August 2017

language of work or name

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1 February 2004

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Biochemistry and Cell Biology

9 August 2017

published in

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9 August 2017

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9 August 2017

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9 August 2017

page(s)

129-144

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The caveolae membrane system

9 August 2017

cites work

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Two sterol regulatory element-like sequences mediate up-regulation of caveolin gene transcription in response to low density lipoprotein free cholesterol

21 January 2018

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Functions of lipid rafts in biological membranes

21 January 2018

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Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

21 January 2018

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Downregulation and altered spatial pattern of caveolin-1 in chronic plaque psoriasis

21 January 2018

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A phosphotyrosine-dependent protein interaction screen reveals a role for phosphorylation of caveolin-1 on tyrosine 14: recruitment of C-terminal Src kinase

21 January 2018

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Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation

21 January 2018

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Lowering the cholesterol content of MA104 cells inhibits receptor-mediated transport of folate

21 January 2018

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Dynamin mediates caveolar sequestration of muscarinic cholinergic receptors and alteration in NO signaling

21 January 2018

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Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth

21 January 2018

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Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain

21 January 2018

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Caveolin-1 down-regulates inducible nitric oxide synthase via the proteasome pathway in human colon carcinoma cells

21 January 2018

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Caveolae and intracellular trafficking of cholesterol

21 January 2018

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Relationship between cholesterol trafficking and signaling in rafts and caveolae

21 January 2018

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Caveolin mRNA levels are up-regulated by free cholesterol and down-regulated by oxysterols in fibroblast monolayers

21 January 2018

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De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin.

21 January 2018

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Calcium pump of the plasma membrane is localized in caveolae

21 January 2018

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Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade

21 January 2018

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Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism.

21 January 2018

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Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton

21 January 2018

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Involvement of VIP36 in intracellular transport and secretion of glycoproteins in polarized Madin-Darby canine kidney (MDCK) cells

21 January 2018

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Selective accumulation of raft-associated membrane protein LAT in T cell receptor signaling assemblies

21 January 2018

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Dynamin-mediated internalization of caveolae.

21 January 2018

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Up-regulated caveolin-1 accentuates the metastasis capability of lung adenocarcinoma by inducing filopodia formation

21 January 2018

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The cyclin D1 gene is transcriptionally repressed by caveolin-1.

21 January 2018

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Caveolins and cellular cholesterol balance

21 January 2018

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Formation of elaborate networks of T-system tubules in cultured skeletal muscle with special reference to the T-system formation

21 January 2018

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Calcium signal transduction from caveolae

21 January 2018

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Concentration of caveolin-1 in the cleavage furrow as revealed by time-lapse analysis

21 January 2018

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Reduction of caveolin and caveolae in oncogenically transformed cells

21 January 2018

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VIP21, a 21-kD membrane protein is an integral component of trans-Golgi-network-derived transport vesicles

21 January 2018

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Involvement of caveolin-2 in caveolar biogenesis in MDCK cells

21 January 2018

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Lipid rafts make for slippery platforms

21 January 2018

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Interleukin 2 receptors and detergent-resistant membrane domains define a clathrin-independent endocytic pathway

21 January 2018

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Identification of reggie-1 and reggie-2 as plasmamembrane-associated proteins which cocluster with activated GPI-anchored cell adhesion molecules in non-caveolar micropatches in neurons

21 January 2018

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Changes in lipid and protein constituents of rafts and caveolae in multidrug resistant cancer cells and their functional consequences

21 January 2018

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Distinct caveolae-mediated endocytic pathways target the Golgi apparatus and the endoplasmic reticulum

21 January 2018

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Caveolin-1 is a negative regulator of caveolae-mediated endocytosis to the endoplasmic reticulum

21 January 2018

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Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette

21 January 2018

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Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia

21 January 2018

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Adapters in lymphocyte signaling

21 January 2018

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Thy-1/CD3 coengagement promotes TCR signaling and enhances particularly tyrosine phosphorylation of the raft molecule LAT.

21 January 2018

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Caveolin transfection results in caveolae formation but not apical sorting of glycosylphosphatidylinositol (GPI)-anchored proteins in epithelial cells.

21 January 2018

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Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease

21 January 2018

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An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators

21 January 2018

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Identification of caveolin-1 in lipoprotein particles secreted by exocrine cells

21 January 2018

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Mechanistic studies with potent and selective inducible nitric-oxide synthase dimerization inhibitors

21 January 2018

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Multiple domains in caveolin-1 control its intracellular traffic

21 January 2018

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Functionally different GPI proteins are organized in different domains on the neuronal surface

21 January 2018

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The MAL proteolipid is necessary for the overall apical delivery of membrane proteins in the polarized epithelial Madin-Darby canine kidney and fischer rat thyroid cell lines

21 January 2018

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Impairment of caveolae formation and T-system disorganization in human muscular dystrophy with caveolin-3 deficiency

21 January 2018

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VIP21-caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro

21 January 2018

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Dual control of caveolar membrane traffic by microtubules and the actin cytoskeleton

21 January 2018

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VIP21/caveolin is a cholesterol-binding protein

21 January 2018

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Caveolae/raft-dependent endocytosis

21 January 2018

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Dynamin at the neck of caveolae mediates their budding to form transport vesicles by GTP-driven fission from the plasma membrane of endothelium

21 January 2018

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Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane

21 January 2018

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Caveolin-1/3 double-knockout mice are viable, but lack both muscle and non-muscle caveolae, and develop a severe cardiomyopathic phenotype.

21 January 2018

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Caveolae--from ultrastructure to molecular mechanisms.

21 January 2018

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Regulated internalization of caveolae

21 January 2018

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Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER

21 January 2018

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A caveolin dominant negative mutant associates with lipid bodies and induces intracellular cholesterol imbalance

21 January 2018

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Clathrin-dependent and -independent internalization of plasma membrane sphingolipids initiates two Golgi targeting pathways

21 January 2018

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Reduction of caveolin 1 gene expression in lung carcinoma cell lines

21 January 2018

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Asymmetric localization of flotillins/reggies in preassembled platforms confers inherent polarity to hematopoietic cells

21 January 2018

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Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor

21 January 2018

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Caveolae: from cell biology to animal physiology

21 January 2018

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Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae

21 January 2018

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Cholesterol controls the clustering of the glycophospholipid-anchored membrane receptor for 5-methyltetrahydrofolate

21 January 2018

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Caveolin, a protein component of caveolae membrane coats

21 January 2018

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Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains

21 January 2018

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Stomatin, flotillin-1, and flotillin-2 are major integral proteins of erythrocyte lipid rafts

21 January 2018

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Caveolin-1 and -2 in the exocytic pathway of MDCK cells.

21 January 2018

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The caveolin triad: caveolae biogenesis, cholesterol trafficking, and signal transduction

21 January 2018

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Functional rafts in cell membranes

21 January 2018

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Lipid rafts and signal transduction

21 January 2018

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Protein kinase C activators inhibit receptor-mediated potocytosis by preventing internalization of caveolae

21 January 2018

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Hormonal regulation of caveolae internalization

21 January 2018

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Caveolins, liquid-ordered domains, and signal transduction

21 January 2018

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The phosphorylation of caveolin-2 on serines 23 and 36 modulates caveolin-1-dependent caveolae formation

21 January 2018

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Identification of filamin as a novel ligand for caveolin-1: evidence for the organization of caveolin-1-associated membrane domains by the actin cytoskeleton

21 January 2018

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Structure and function of endothelial caveolae.

21 January 2018

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Glycosylphosphatidyl inositol-anchored proteins and fyn kinase assemble in noncaveolar plasma membrane microdomains defined by reggie-1 and -2

21 January 2018

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The SPFH domain: implicated in regulating targeted protein turnover in stomatins and other membrane-associated proteins

21 January 2018

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Caveolae are highly immobile plasma membrane microdomains, which are not involved in constitutive endocytic trafficking

21 January 2018

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Transcytosis: crossing cellular barriers

21 January 2018

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Characterization of a cytosolic heat-shock protein-caveolin chaperone complex. Involvement in cholesterol trafficking

21 January 2018

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Caveolae: anchored, multifunctional platforms in the lipid ocean

21 January 2018

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Visualization of caveolin-1, a caveolar marker protein, in living cells using green fluorescent protein (GFP) chimeras. The subcellular distribution of caveolin-1 is modulated by cell-cell contact

21 January 2018

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Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr(14)) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic

21 January 2018

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Expression of caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts

21 January 2018

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A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth

21 January 2018

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Caveolin-1 is down-regulated in human ovarian carcinoma and acts as a candidate tumor suppressor gene

21 January 2018

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Down-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcomas

21 January 2018

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Second cysteine-rich region of epidermal growth factor receptor contains targeting information for caveolae/rafts

21 January 2018

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Caveolae and caveolae-like membrane domains in cellular signaling and disease: identification of downstream targets for the tumor suppressor protein caveolin-1.

21 January 2018

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Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells

21 January 2018

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A Molecular Sensor Detects Signal Transduction from Caveolae in Living Cells

21 January 2018

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Lipid rafts: cell surface platforms for T cell signaling

21 January 2018

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Posttranslational protein S-palmitoylation and the compartmentalization of signaling molecules in neurons

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/O03-071

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9 August 2017

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