Down-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcomas (Q28359685)

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C Sers

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K Arlt

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M Dietel

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P M Schlag

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U Schneider

The American Journal of Pathology

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language of work or name

English

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publication date

March 2001

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published in

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volume

158

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issue

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page(s)

833-9

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cites work

Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5' promoter region of the caveolin-1 gene in human breast cancer cell lines

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Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers

20 March 2017

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(C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer

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Caveolin-1 isoforms are encoded by distinct mRNAs. Identification Of mouse caveolin-1 mRNA variants caused by alternative transcription initiation and splicing

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A rapid, sensitive, and specific method for the determination of protein in dilute solution

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Caveolin-1 is regulated by c-myc and suppresses c-myc-induced apoptosis

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beta-catenin expression pattern in stage I and II ovarian carcinomas : relationship with beta-catenin gene mutations, clinicopathological features, and clinical outcome

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Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade

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Caveolae and caveolins

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Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease

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Caveolae: static inpocketings of the plasma membrane, dynamic vesicles or plain artifact?

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Positive selection of candidate tumor-suppressor genes by subtractive hybridization

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p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity

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Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines

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Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane

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Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth

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Tyrosine phosphorylation of a 22-kDa protein is correlated with transformation by Rous sarcoma virus

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Activated N-ras controls the transformed phenotype of HT1080 human fibrosarcoma cells.

2 June 2018

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Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1)

27 November 2018

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Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells

7 January 2021

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Loss of heterozygosity on the long arm of human chromosome 7 in sporadic renal cell carcinomas

7 January 2021

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Caveolin-1 modulates the activity of the volume-regulated chloride channel

7 January 2021

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Caveolin-1 expression in clinically confined human prostate cancer: a novel prognostic marker

7 January 2021

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PubMed

https://pubmed.ncbi.nlm.nih.gov/11238032

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Frequent loss of heterozygosity in human primary squamous cell and colon carcinomas at 7q31.1: evidence for a broad range tumor suppressor gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11238032

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A molecular cytogenetic analysis of 7q31 in prostate cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11238032

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/S0002-9440(10)64031-X

1 reference

1 reference

1 reference

PubMed publication ID

11238032

1 reference