Gq signaling causes glomerular injury by activating TRPC6. (Q35719874)

9 August 2017

title

Gq signaling causes glomerular injury by activating TRPC6. (English)

1 reference

9 August 2017

Liming Wang

1 reference

9 August 2017

Grant Jirka

1 reference

9 August 2017

Paul B Rosenberg

1 reference

9 August 2017

Anne F Buckley

1 reference

9 August 2017

Jose A Gomez

1 reference

9 August 2017

Timothy A Fields

1 reference

9 August 2017

Michelle P Winn

1 reference

9 August 2017

Robert F Spurney

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9 August 2017

language of work or name

English

0 references

publication date

6 April 2015

1 reference

Journal of Clinical Investigation

9 August 2017

published in

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9 August 2017

volume

125

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9 August 2017

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9 August 2017

page(s)

1913-1926

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Nox family NADPH oxidases: Molecular mechanisms of activation

9 August 2017

cites work

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ATP acting through P2Y receptors causes activation of podocyte TRPC6 channels: role of podocin and reactive oxygen species

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Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease.

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Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway.

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Activation of RhoA in podocytes induces focal segmental glomerulosclerosis

12 July 2018

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Calcium Mediates Glomerular Filtration through Calcineurin and mTORC2/Akt Signaling

12 July 2018

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12 July 2018

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Calcineurin (CN) Activation Promotes Apoptosis of Glomerular Podocytes Both in Vitro and in Vivo

12 July 2018

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Addition of atrasentan to renin-angiotensin system blockade reduces albuminuria in diabetic nephropathy

12 July 2018

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12 July 2018

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TRPC channel modulation in podocytes—inching toward novel treatments for glomerular disease

12 July 2018

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Antagonistic Regulation of Actin Dynamics and Cell Motility by TRPC5 and TRPC6 Channels

12 July 2018

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Podocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease

12 July 2018

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Activation of NFAT signaling in podocytes causes glomerulosclerosis

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription.

12 July 2018

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12 July 2018

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12 July 2018

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Gq-dependent signaling upregulates COX2 in glomerular podocytes

12 July 2018

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12 July 2018

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12 July 2018

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TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

12 July 2018

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A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Identifiers

DOI

10.1172/JCI76767

1 reference

9 August 2017

1 reference

9 August 2017

1 reference