Podocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease (Q33705025)

28 July 2017

title

Podocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease (English)

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28 July 2017

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Paulina Carmona-Mora

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28 July 2017

Katherina Walz

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28 July 2017

Changli Wei

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28 July 2017

Paola Krall

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28 July 2017

Cesar P Canales

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28 July 2017

Pamela Kairath

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28 July 2017

Jessica Molina

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28 July 2017

J Daniel Carpio

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28 July 2017

Phillip Ruiz

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28 July 2017

Sergio A Mezzano

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28 July 2017

Jing Li

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28 July 2017

Jochen Reiser

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28 July 2017

Juan I Young

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28 July 2017

language of work or name

English

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publication date

20 September 2010

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28 July 2017

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

e12859

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Creative Commons Attribution 4.0 International

28 July 2017

start time

20 September 2010

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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A novel TRPC6 mutation that causes childhood FSGS.

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Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis

21 June 2018

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Focal segmental glomerulosclerosis: a morphologic diagnosis in evolution

21 June 2018

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TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription.

21 June 2018

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MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis

21 June 2018

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Tetracycline-inducible gene expression in conditionally immortalized mouse podocytes

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The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A.

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The spectrum of focal segmental glomerulosclerosis: new insights

21 June 2018

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Podocyte injury in focal segmental glomerulosclerosis: Lessons from animal models (a play in five acts).

21 June 2018

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A common mechanism underlies stretch activation and receptor activation of TRPC6 channels

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin

21 June 2018

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Human TRPC6 expressed in HEK 293 cells forms non-selective cation channels with limited Ca2+ permeability

21 June 2018

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Na(+) entry and modulation of Na(+)/Ca(2+) exchange as a key mechanism of TRPC signaling

21 June 2018

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TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

21 June 2018

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A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis

21 June 2018

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Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension

21 June 2018

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Early glomerular filtration defect and severe renal disease in podocin-deficient mice

21 June 2018

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TRP channels as cellular sensors

21 June 2018

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Inducible podocyte-specific gene expression in transgenic mice.

21 June 2018

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Trends in the epidemiology of focal segmental glomerulosclerosis

21 June 2018

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Animal models of FSGS: Lessons for pathogenesis and treatment

21 June 2018

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The genetic basis of FSGS and steroid-resistant nephrosis

21 June 2018

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The TRP channels, a remarkably functional family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN

21 June 2018

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Lupus-like kidney disease in mice deficient in the Src family tyrosine kinases Lyn and Fyn.

21 June 2018

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The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death

21 June 2018

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NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

The role of the podocyte in glomerulosclerosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7. Ca(2+)-permeable cation channel that is constitutively activated and enhanced by stimulation of G protein-coupled receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

Cloning and expression of a novel mammalian homolog of Drosophila transient receptor potential (Trp) involved in calcium entry secondary to activation of receptors coupled by the Gq class of G protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

TRPC6 mutational analysis in a large cohort of patients with focal segmental glomerulosclerosis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

Podocyte cell-specific expression of doxycycline inducible Cre recombinase in mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

Two gene fragments that direct podocyte-specific expression in transgenic mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

Podocyte-specific expression of cre recombinase in transgenic mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

Congenital nephrotic syndrome in mice lacking CD2-associated protein

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2942896

NPHS2 mutations in adult patients with primary focal segmental glomerulosclerosis

30 October 2018

1 reference

12 December 2020

The glomerular slit diaphragm is a modified adherens junction

1 reference

12 December 2020

Focal and segmental glomerulosclerosis in mice with podocyte-specific expression of mutant alpha-actinin-4

1 reference

12 December 2020

Induction of TRPC6 channel in acquired forms of proteinuric kidney disease

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0012859

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DOI

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28 July 2017

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28 July 2017

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