Exosomes in human semen restrict HIV-1 transmission by vaginal cells and block intravaginal replication of LP-BM5 murine AIDS virus complex (Q35706820)

9 August 2017

title

Exosomes in human semen restrict HIV-1 transmission by vaginal cells and block intravaginal replication of LP-BM5 murine AIDS virus complex (English)

1 reference

9 August 2017

0 references

Philip H Jones

0 references

Chioma M Okeoma

0 references

Marisa N Madison

1 reference

9 August 2017

language of work or name

English

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publication date

13 April 2015

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9 August 2017

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9 August 2017

volume

482

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9 August 2017

page(s)

189-201

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Human semen contains exosomes with potent anti-HIV-1 activity.

9 August 2017

cites work

1 reference

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Oral and vaginal epithelial cell lines bind and transfer cell-free infectious HIV-1 to permissive cells but are not productively infected

12 July 2018

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Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

12 July 2018

1 reference

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Transcytosis of HIV-1 through vaginal epithelial cells is dependent on trafficking to the endocytic recycling pathway

12 July 2018

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12 July 2018

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The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells

12 July 2018

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Serum extracellular vesicle protein levels are associated with acute coronary syndrome

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12 July 2018

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Exosomes derived from Epstein-Barr virus-infected cells are internalized via caveola-dependent endocytosis and promote phenotypic modulation in target cells.

12 July 2018

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Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity

12 July 2018

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Human placental trophoblasts confer viral resistance to recipient cells

12 July 2018

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BST-2/tetherin is overexpressed in mammary gland and tumor tissues in MMTV-induced mammary cancer.

12 July 2018

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BST-2/tetherin-mediated restriction of chikungunya (CHIKV) VLP budding is counteracted by CHIKV non-structural protein 1 (nsP1)

12 July 2018

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Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.

12 July 2018

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IFN-α and lipopolysaccharide upregulate APOBEC3 mRNA through different signaling pathways.

12 July 2018

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Exosomal cell-to-cell transmission of alpha synuclein oligomers.

12 July 2018

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A novel role for APOBEC3: susceptibility to sexual transmission of murine acquired immunodeficiency virus (mAIDS) is aggravated in APOBEC3 deficient mice.

12 July 2018

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Bone marrow stromal cell antigen 2 (BST-2) restricts mouse mammary tumor virus (MMTV) replication in vivo

12 July 2018

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Generation of transmitted/founder HIV-1 infectious molecular clones and characterization of their replication capacity in CD4 T lymphocytes and monocyte-derived macrophages

12 July 2018

1 reference

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Vaginal langerhans cells nonproductively transporting HIV-1 mediate infection of T cells

12 July 2018

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Intercellular nanovesicle-mediated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth

12 July 2018

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Body fluid derived exosomes as a novel template for clinical diagnostics

12 July 2018

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Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

12 July 2018

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Innate and adaptive immunity at mucosal surfaces of the female reproductive tract: stratification and integration of immune protection against the transmission of sexually transmitted infections

12 July 2018

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A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes

12 July 2018

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Glycerol monolaurate prevents mucosal SIV transmission

12 July 2018

1 reference

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Induction of APOBEC3 in vivo causes increased restriction of retrovirus infection.

12 July 2018

1 reference

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Macrophages in vaginal but not intestinal mucosa are monocyte-like and permissive to human immunodeficiency virus type 1 infection

12 July 2018

1 reference

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Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

12 July 2018

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Exosomes packaging APOBEC3G confer human immunodeficiency virus resistance to recipient cells

12 July 2018

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Proteomic profiling of exosomes: current perspectives

12 July 2018

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Exosome function: from tumor immunology to pathogen biology

12 July 2018

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APOBEC3G inhibits DNA strand transfer during HIV-1 reverse transcription.

12 July 2018

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Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1.

12 July 2018

1 reference

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APOBEC3 inhibits mouse mammary tumour virus replication in vivo.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4461544

Inhibition of dynamin completely blocks compensatory synaptic vesicle endocytosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4461544

Dendritic-cell interactions with HIV: infection and viral dissemination

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4461544

Cell-free human immunodeficiency virus type 1 transcytosis through primary genital epithelial cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4461544

R5- and X4-HIV-1 use differentially the endometrial epithelial cells HEC-1A to ensure their own spread: implication for mechanisms of sexual transmission

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4461544

Innate and adaptive immunity in female genital tract: cellular responses and interactions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4461544

Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4461544

The innate immune system is activated by stimulation of vaginal epithelial cells with Staphylococcus aureus and toxic shock syndrome toxin 1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4461544

Transmission of HIV-1 by primary human uterine epithelial cells and stromal fibroblasts

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4461544

Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4461544

The biogenesis of multivesicular endosomes

12 July 2018

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Lipid rafts and HIV pathogenesis: virion-associated cholesterol is required for fusion and infection of susceptible cells

12 July 2018

1 reference

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Antiretroviral therapy to reduce the sexual transmission of HIV.

12 July 2018

1 reference

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Memory CD4(+) T cells are the earliest detectable human immunodeficiency virus type 1 (HIV-1)-infected cells in the female genital mucosal tissue during HIV-1 transmission in an organ culture system

12 July 2018

1 reference

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Male viral load and heterosexual transmission of HIV-1 subtype E in northern Thailand

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4461544

The large GTPase dynamin regulates actin comet formation and movement in living cells

12 July 2018

1 reference

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Reducing the risk of sexual HIV transmission: quantifying the per-act risk for HIV on the basis of choice of partner, sex act, and condom use.

12 July 2018

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Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 transcytosis across human epithelial cells

12 July 2018

1 reference

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12 July 2018

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Reduced antiretroviral drug susceptibility among patients with primary HIV infection

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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HIV-1 in semen: an isolated virus reservoir

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Extracellular organelles (prostasomes) are immunosuppressive components of human semen

12 July 2018

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Cell-to-cell spread of HIV-1 occurs within minutes and may not involve the participation of virus particles

12 July 2018

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Isolation of circulating microRNAs from microvesicles found in human plasma.

12 July 2018

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25 September 2018

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25 September 2018

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25 September 2018

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gp340 expressed on human genital epithelia binds HIV-1 envelope protein and facilitates viral transmission.

25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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Genital tract HIV-1 RNA shedding among women with below detectable plasma viral load

7 January 2021

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7 January 2021

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Sexual Transmission and Propagation of SIV and HIV in Resting and Activated CD4+ T Cells

7 January 2021

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7 January 2021

Identifiers

DOI

1 reference

9 August 2017

1 reference

9 August 2017

1 reference