Vectored antibody gene delivery for the prevention or treatment of HIV infection (Q35664155)

9 August 2017

1 reference

title

Vectored antibody gene delivery for the prevention or treatment of HIV infection (English)

1 reference

9 August 2017

0 references

prevention of HIV/AIDS

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25700206%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Cailin E Deal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25700206%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

publication date

1 May 2015

1 reference

25700206

Current Opinion in HIV and AIDS

9 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25700206%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25700206%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25700206%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

page(s)

190-197

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25700206%20AND%20SRC:MED&resulttype=core&format=json

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

3 June 2020

cites work

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12 July 2018

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12 July 2018

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12 July 2018

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Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice

12 July 2018

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12 July 2018

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Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor

12 July 2018

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12 July 2018

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12 July 2018

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Targeted cytotoxic therapy kills persisting HIV infected cells during ART

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

12 July 2018

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AAV8 induces tolerance in murine muscle as a result of poor APC transduction, T cell exhaustion, and minimal MHCI upregulation on target cells.

12 July 2018

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New developments in lentiviral vector design, production and purification

12 July 2018

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Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

12 July 2018

1 reference

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Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies

12 July 2018

1 reference

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HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

12 July 2018

1 reference

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Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo

12 July 2018

1 reference

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Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape

12 July 2018

1 reference

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Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice

12 July 2018

1 reference

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Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies

12 July 2018

1 reference

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scFv antibody: principles and clinical application

12 July 2018

1 reference

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Determinants of per-coital-act HIV-1 infectivity among African HIV-1-serodiscordant couples

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Adenovirus-associated virus vector-mediated gene transfer in hemophilia B

12 July 2018

1 reference

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Antibody-based protection against HIV infection by vectored immunoprophylaxis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

12 July 2018

1 reference

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Enhancing the Clinical Potential of AAV Vectors by Capsid Engineering to Evade Pre-Existing Immunity

12 July 2018

1 reference

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H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination

12 July 2018

1 reference

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12 July 2018

1 reference

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Single-chain Fv-based anti-HIV proteins: potential and limitations

12 July 2018

1 reference

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Broad neutralization coverage of HIV by multiple highly potent antibodies

12 July 2018

1 reference

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Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

12 July 2018

1 reference

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Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

12 July 2018

1 reference

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Humanized Rag1-/- γc-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routes

12 July 2018

1 reference

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Impact of pre-existing immunity on gene transfer to nonhuman primate liver with adeno-associated virus 8 vectors

12 July 2018

1 reference

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The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection

12 July 2018

1 reference

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Characteristics of the earliest cross-neutralizing antibody response to HIV-1.

12 July 2018

1 reference

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Dimeric 2G12 as a potent protection against HIV-1.

12 July 2018

1 reference

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Passive neutralizing antibody controls SHIV viremia and enhances B cell responses in infant macaques.

12 July 2018

1 reference

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Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

12 July 2018

1 reference

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Clinical pharmacokinetics of therapeutic monoclonal antibodies

12 July 2018

1 reference

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Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Inhibition of in vivo HIV infection in humanized mice by gene therapy of human hematopoietic stem cells with a lentiviral vector encoding a broadly neutralizing anti-HIV antibody

12 July 2018

1 reference

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Enhanced antibody half-life improves in vivo activity

12 July 2018

1 reference

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Effect of genome size on AAV vector packaging

12 July 2018

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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

12 July 2018

1 reference

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Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys

12 July 2018

1 reference

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Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies

12 July 2018

1 reference

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Functional and phenotypic characterization of the humanized BLT mouse model

12 July 2018

1 reference

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Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice

12 July 2018

1 reference

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Adjunctive passive immunotherapy in human immunodeficiency virus type 1-infected individuals treated with antiviral therapy during acute and early infection

12 July 2018

1 reference

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Preclinical and clinical safety of monoclonal antibodies

12 July 2018

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An antibody delivery system for regulated expression of therapeutic levels of monoclonal antibodies in vivo

12 July 2018

1 reference

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Anti-V3 humanized antibody KD-247 effectively suppresses ex vivo generation of human immunodeficiency virus type 1 and affords sterile protection of monkeys against a heterologous simian/human immunodeficiency virus infection

12 July 2018

1 reference

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Directed evolution of adeno-associated virus yields enhanced gene delivery vectors

12 July 2018

1 reference

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AAV hybrid serotypes: improved vectors for gene delivery

12 July 2018

1 reference

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Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.

12 July 2018

1 reference

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Immunogenicity of engineered antibodies

12 July 2018

1 reference

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Stable antibody expression at therapeutic levels using the 2A peptide

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Passive immunotherapy in simian immunodeficiency virus-infected macaques accelerates the development of neutralizing antibodies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Inhibiting sexual transmission of HIV-1 infection

12 July 2018

1 reference

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Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

12 July 2018

1 reference

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Generation of neutralizing activity against human immunodeficiency virus type 1 in serum by antibody gene transfer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Clinical trials of antibody therapy

12 July 2018

1 reference

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Neutralizing antibodies have limited effects on the control of established HIV-1 infection in vivo.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Quantitative analysis of the packaging capacity of recombinant adeno-associated virus

12 July 2018

1 reference

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Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG.

12 July 2018

1 reference

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Epidemiology of adenovirus-associated virus infection in a nursery population

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Characterization of the cDNA of a broadly reactive neutralizing human anti-gp120 monoclonal antibody

12 July 2018

1 reference

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Endgame: glybera finally recommended for approval as the first gene therapy drug in the European union

12 July 2018

1 reference

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Unraveling the divergent results of pre-exposure prophylaxis trials for HIV prevention

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population: implications for gene therapy using AAV vectors

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Engineering human hematopoietic stem/progenitor cells to produce a broadly neutralizing anti-HIV antibody after in vitro maturation to human B lymphocytes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Self-complementary recombinant adeno-associated viral vectors: packaging capacity and the role of rep proteins in vector purity.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Evidence of multiyear factor IX expression by AAV-mediated gene transfer to skeletal muscle in an individual with severe hemophilia B.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

A phase I trial with two human monoclonal antibodies (hMAb 2F5, 2G12) against HIV-1.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Phase I Study of a Human Monoclonal Antibody Directed against the CD4-Binding Site of HIV Type 1 Glycoprotein 120

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448693

Immune deposits in extraglomerular vessels: their correlation with circulating immune complexes

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25700206

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1097/COH.0000000000000145

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25700206%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25700206%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

25700206

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25700206%20AND%20SRC:MED&resulttype=core&format=json