Stable antibody expression at therapeutic levels using the 2A peptide (Q40434248)

20 September 2017

title

Stable antibody expression at therapeutic levels using the 2A peptide (English)

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20 September 2017

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Jianmin Fang

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20 September 2017

Jing-Jing Qian

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20 September 2017

Saili Yi

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20 September 2017

Thomas C Harding

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20 September 2017

Guang Huan Tu

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20 September 2017

Melinda VanRoey

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20 September 2017

Karin Jooss

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20 September 2017

publication date

17 April 2005

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20 September 2017

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20 September 2017

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20 September 2017

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20 September 2017

page(s)

584-590

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20 September 2017

cites work

Engineered antibodies

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Antibody engineering via genetic engineering of the mouse: XenoMouse strains are a vehicle for the facile generation of therapeutic human monoclonal antibodies

21 January 2018

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From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy

21 January 2018

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IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector

21 January 2018

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Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

21 January 2018

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Co-translational, intraribosomal cleavage of polypeptides by the foot-and-mouth disease virus 2A peptide

21 January 2018

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Efficient selection for high-expression transfectants with a novel eukaryotic vector

21 January 2018

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Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

21 January 2018

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Therapeutic antibody gene transfer: an active approach to passive immunity

21 January 2018

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A phase I trial with two human monoclonal antibodies (hMAb 2F5, 2G12) against HIV-1.

21 January 2018

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Regulatable systemic production of monoclonal antibodies by in vivo muscle electroporation

21 January 2018

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In vitro and in vivo secretion of cloned antibodies by genetically modified myogenic cells

21 January 2018

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Generation of neutralizing activity against human immunodeficiency virus type 1 in serum by antibody gene transfer

21 January 2018

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Immunity to adenovirus and adeno-associated viral vectors: implications for gene therapy

21 January 2018

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Safety of adeno-associated virus gene therapy vectors: a current evaluation

21 January 2018

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Recombinant adeno-associated virus as delivery vector for gene therapy--a review

21 January 2018

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Immune responses to recombinant adeno-associated virus vectors: putting preclinical findings into perspective

21 January 2018

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Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial

21 January 2018

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AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.

21 January 2018

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Clinical protocol. Gene therapy of Canavan disease: AAV-2 vector for neurosurgical delivery of aspartoacylase gene (ASPA) to the human brain

21 January 2018

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Subthalamic GAD gene therapy in a Parkinson's disease rat model

21 January 2018

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Cleavage of foot-and-mouth disease virus polyprotein is mediated by residues located within a 19 amino acid sequence

21 January 2018

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Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

21 January 2018

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The cleavage activities of aphthovirus and cardiovirus 2A proteins

21 January 2018

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7 January 2021

Analysis of the aphthovirus 2A/2B polyprotein ‘cleavage’ mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal ‘skip’

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7 January 2021

Targeting of proteins derived from self-processing polyproteins containing multiple signal sequences

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7 January 2021

Rituximab anti-CD20 monoclonal antibody therapy in non-Hodgkin's lymphoma: safety and efficacy of re-treatment

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7 January 2021

Sustained Systemic Delivery of Monoclonal Antibodies by Genetically Modified Skin Fibroblasts

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7 January 2021

High In Vivo Production of a Model Monoclonal Antibody on Adenoviral Gene Transfer

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7 January 2021

Identifiers

DOI

10.1038/NBT1087

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release_ndg65vc5evfqvneyr4f4cvusfe

20 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/ndg65vc5evfqvneyr4f4cvusfe

24 November 2022

mapped directly with Wikidata item

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