Absence of Stat1 in donor CD4⁺ T cells promotes the expansion of Tregs and reduces graft-versus-host disease in mice (Q35572384)

8 August 2017

title

Absence of Stat1 in donor CD4⁺ T cells promotes the expansion of Tregs and reduces graft-versus-host disease in mice (English)

1 reference

8 August 2017

Huihui Ma

1 reference

8 August 2017

Caisheng Lu

1 reference

8 August 2017

Judith Ziegler

1 reference

8 August 2017

Ailing Liu

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8 August 2017

Antonia Sepulveda

1 reference

8 August 2017

Hideho Okada

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8 August 2017

Suzanne Lentzsch

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8 August 2017

Markus Y Mapara

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8 August 2017

language of work or name

English

0 references

publication date

13 June 2011

1 reference

Journal of Clinical Investigation

8 August 2017

published in

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8 August 2017

volume

121

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8 August 2017

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8 August 2017

page(s)

2554-2569

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Role of type 1 IFNs in antiglioma immunosurveillance--using mouse studies to guide examination of novel prognostic markers in humans

8 August 2017

cites work

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

12 July 2018

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12 July 2018

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Interferon alpha/beta synthesis during acute graft-versus-host disease

12 July 2018

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Antibodies to IFN-gamma prevent immunologically mediated intestinal damage in murine graft-versus-host reaction

12 July 2018

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Absence of IL-23p19 in donor allogeneic cells reduces mortality from acute GVHD.

12 July 2018

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Dendritic cells require STAT-1 phosphorylated at its transactivating domain for the induction of peptide-specific CTL.

26 September 2018

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26 September 2018

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IFN-gamma-STAT1 signal regulates the differentiation of inducible Treg: potential role for ROS-mediated apoptosis

26 September 2018

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Stable long-term donor engraftment following reduced-intensity hematopoietic cell transplantation for sickle cell disease

26 September 2018

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STAT1 signaling in CD8 T cells is required for their clonal expansion and memory formation following viral infection in vivo.

26 September 2018

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26 September 2018

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Reduction of graft-versus-host disease by histone deacetylase inhibitor suberonylanilide hydroxamic acid is associated with modulation of inflammatory cytokine milieu and involves inhibition of STAT1.

26 September 2018

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Cutting edge: role of STAT1, STAT3, and STAT5 in IFN-alpha beta responses in T lymphocytes

26 September 2018

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Alternative activation of STAT1 and STAT3 in response to interferon-gamma

26 September 2018

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A linear signal transduction pathway involving phosphatidylinositol 3-kinase, protein kinase Cepsilon, and MAPK in mesangial cells regulates interferon-gamma-induced STAT1alpha transcriptional activation

26 September 2018

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CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation

26 September 2018

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Macrophage inflammatory protein 1-alpha (MIP-1 alpha ) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells

26 September 2018

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IFN differentially controls the development of idiopathic pneumonia syndrome and GVHD of the gastrointestinal tract

26 September 2018

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T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

7 December 2018

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12 December 2020

STAT1 expression in dendritic cells, but not T cells, is required for immunity to Leishmania major

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12 December 2020

Interferon-gamma induces X-linked inhibitor of apoptosis-associated factor-1 and Noxa expression and potentiates human vascular smooth muscle cell apoptosis by STAT3 activation

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12 December 2020

Role of CXCR3-induced donor T-cell migration in acute GVHD

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12 December 2020

Increase in FOXP3+ Regulatory T Cells in GVHD Skin Biopsies Is Associated with Lower Disease Severity and Treatment Response

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12 December 2020

Bone-marrow transplantation in non-malignant disease

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12 December 2020

Enhanced interferon-alpha/beta (IFN-alpha/beta) and defective IFN-gamma production in chronic graft versus host disease: a potential mechanism for immunosuppression

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12 December 2020

The role of alpha interferon in the pathogenesis of GVHD

1 reference

12 December 2020

An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes

1 reference

12 December 2020

Interferons up-regulate STAT1, STAT2, and IRF family transcription factor gene expression in human peripheral blood mononuclear cells and macrophages

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12 December 2020

Prevention of graft versus host disease by inactivation of host antigen-presenting cells

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12 December 2020

Cutting edge: differentiation of antitumor CTL in vivo requires host expression of Stat1

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12 December 2020

Expression of chemokines in GVHD target organs is influenced by conditioning and genetic factors and amplified by GVHR

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12 December 2020

Opposing roles of interferon-gamma on CD4+ T cell-mediated graft-versus-host disease: effects of conditioning

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12 December 2020

Donor-derived interferon gamma separates graft-versus-leukemia effects and graft-versus-host disease induced by donor CD8 T cells

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12 December 2020

Identifiers

DOI

10.1172/JCI43706

1 reference

8 August 2017

1 reference

8 August 2017

1 reference