A functional landscape of resistance to ALK inhibition in lung cancer (Q35438912)

8 August 2017

title

A functional landscape of resistance to ALK inhibition in lung cancer (English)

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8 August 2017

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Jill P Mesirov

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8 August 2017

Mohit Butaney

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Antonio Calles

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Marzia Capelletti

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Matthew Meyerson

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Stacey B Gabriel

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8 August 2017

Pasi A Jänne

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8 August 2017

Levi A Garraway

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8 August 2017

Pablo Tamayo

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8 August 2017

William C Hahn

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8 August 2017

David E Root

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8 August 2017

Federica Piccioni

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8 August 2017

Cory M Johannessen

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8 August 2017

Eliezer M Van Allen

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8 August 2017

Jeffrey A Engelman

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8 August 2017

Frederick H Wilson

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8 August 2017

Jong Wook Kim

series ordinal

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8 August 2017

Steven M Corsello

series ordinal

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8 August 2017

Tanaz Sharifnia

series ordinal

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8 August 2017

language of work or name

English

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publication date

1 March 2015

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8 August 2017

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8 August 2017

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8 August 2017

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8 August 2017

page(s)

397-408

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Patient-derived models of acquired resistance can identify effective drug combinations for cancer.

8 August 2017

cites work

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Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer

27 July 2018

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Receptor ligand-triggered resistance to alectinib and its circumvention by Hsp90 inhibition in EML4-ALK lung cancer cells.

27 July 2018

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The ALK Inhibitor Ceritinib Overcomes Crizotinib Resistance in Non-Small Cell Lung Cancer

27 July 2018

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27 July 2018

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27 July 2018

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The EGFR family members sustain the neoplastic phenotype of ALK+ lung adenocarcinoma via EGR1.

27 July 2018

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MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling

27 July 2018

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Rescue screens with secreted proteins reveal compensatory potential of receptor tyrosine kinases in driving cancer growth

27 July 2018

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Activation of HER family signaling as a mechanism of acquired resistance to ALK inhibitors in EML4-ALK-positive non-small cell lung cancer

27 July 2018

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Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor resistance in EML4-ALK lung cancer cells.

27 July 2018

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

27 July 2018

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Mechanisms of acquired crizotinib resistance in ALK-rearranged lung Cancers

27 July 2018

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27 July 2018

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A novel ALK secondary mutation and EGFR signaling cause resistance to ALK kinase inhibitors

27 July 2018

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27 July 2018

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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

27 July 2018

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27 July 2018

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Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors

27 July 2018

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27 July 2018

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27 July 2018

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An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer

27 July 2018

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Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations

26 September 2018

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Epithelial wounds induce differential phosphorylation changes in response to purinergic and EGF receptor activation

26 September 2018

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Purines, purinergic receptors, and cancer

26 September 2018

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Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.

26 September 2018

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Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer.

26 September 2018

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26 September 2018

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P2Y6 Receptors and ADAM17 Mediate Low-Dose Gamma-Ray-Induced Focus Formation (Activation) of EGF Receptor

26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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10.1016/J.CCELL.2015.02.005

26 September 2018

Identifiers

DOI

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8 August 2017

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8 August 2017

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