Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP. (Q35191064)

7 August 2017

title

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP. (English)

1 reference

7 August 2017

Andrew G Brooks

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Andrew M Lew

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Anthony W Purcell

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Balasubramanian Krishnamurthy

1 reference

7 August 2017

Nadine L Dudek

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7 August 2017

Mark D McKenzie

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7 August 2017

Shane Gellert

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7 August 2017

Peter G Colman

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7 August 2017

Leonard C Harrison

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7 August 2017

Helen E Thomas

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7 August 2017

Thomas W H Kay

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7 August 2017

language of work or name

English

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publication date

1 December 2006

1 reference

Journal of Clinical Investigation

7 August 2017

published in

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7 August 2017

volume

116

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7 August 2017

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7 August 2017

page(s)

3258-3265

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Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide

7 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens

28 July 2018

1 reference

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Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

Epitope spreading in immune-mediated diseases: implications for immunotherapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

IFN-gamma action on pancreatic beta cells causes class I MHC upregulation but not diabetes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

Spontaneous Autoimmune Diabetes in Monoclonal T Cell Nonobese Diabetic Mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells

28 July 2018

1 reference

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Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis.

28 July 2018

1 reference

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Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

Normal incidence of diabetes in NOD mice tolerant to glutamic acid decarboxylase

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

A novel bulk-culture method for generating mature dendritic cells from mouse bone marrow cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

Progression of autoimmune diabetes driven by avidity maturation of a T-cell population

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1679712

Recessive tolerance to preproinsulin 2 reduces but does not abolish type 1 diabetes

15 November 2018

1 reference

12 December 2020

Insulin-dependent diabetes mellitus

1 reference

12 December 2020

Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice

1 reference

12 December 2020

A Novel Micro-assay for Insulin Autoantibodies

1 reference

12 December 2020

Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study

1 reference

12 December 2020

Identification of CD4+ T cell-specific epitopes of islet-specific glucose-6-phosphatase catalytic subunit-related protein: a novel beta cell autoantigen in type 1 diabetes

1 reference

12 December 2020

Islet autoimmunity in infants with a Type I diabetic relative is common but is frequently restricted to one autoantibody

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI29602

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7 August 2017

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7 August 2017

1 reference