Systemic lupus erythematosus and apoptosis: a question of balance (Q35148616)

6 August 2017

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title

Systemic lupus erythematosus and apoptosis: a question of balance (English)

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systemic lupus erythematosus

6 August 2017

main subject

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Dror Mevorach

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6 August 2017

publication date

1 August 2003

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Clinical Reviews in Allergy & Immunology

6 August 2017

published in

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6 August 2017

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6 August 2017

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6 August 2017

page(s)

49-60

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Serial killers: ordering caspase activation events in apoptosis

6 August 2017

cites work

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12 December 2020

Enhancement of macrophage phagocytosis upon iC3b deposition on apoptotic cells

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12 December 2020

Opsonization of apoptotic cells. Implications for uptake and autoimmunity

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12 December 2020

Accelerated Fas-mediated apoptosis of monocytes and maturing macrophages from patients with systemic lupus erythematosus: relevance to in vitro impairment of interaction with iC3b-opsonized apoptotic cells

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12 December 2020

Light and electron microscope study of osmotically induced tumor necrosis

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12 December 2020

The receptor for the cytotoxic ligand TRAIL

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12 December 2020

Cross-priming of naive CD8 T cells against melanoma antigens using dendritic cells loaded with killed allogeneic melanoma cells.

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12 December 2020

Cell death: the significance of apoptosis

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12 December 2020

Cytokine production by macrophages in association with phagocytosis of etoposide-treated P388 cells in vitro and in vivo

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12 December 2020

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

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12 December 2020

Apoptotic cell clearance in systemic lupus erythematosus. I. Opsonization by antiphospholipid antibodies

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12 December 2020

Phagocytosis and clearance of apoptotic cells is mediated by MER.

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12 December 2020

A central role for thymic emigrants in peripheral T cell homeostasis

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12 December 2020

High levels of circulating early apoptic peripheral blood mononuclear cells in systemic lupus erythematosus

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12 December 2020

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

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12 December 2020

LARD: a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing

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12 December 2020

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

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12 December 2020

Phagocytosis promotes programmed cell death in C. elegans

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12 December 2020

Nucleosomes and DNA bind to specific cell-surface molecules on murine cells and induce cytokine production

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12 December 2020

TRAIL/Apo-2 ligand induces primary plasma cell apoptosis

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12 December 2020

Expression and Function of Fas Antigen and bcl-2 in Human Systemic Lupus Erythematosus Lymphocytes

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12 December 2020

The induction of tolerance by dendritic cells that have captured apoptotic cells

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12 December 2020

Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus

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12 December 2020

Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages

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12 December 2020

C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells

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12 December 2020

Mononuclear phagocyte function in SLE. I. Bipartite Fc- and complement-dependent dysfunction

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12 December 2020

Macrophage phagocytosis of wound neutrophils.

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12 December 2020

CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans

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12 December 2020

Systemic exposure to irradiated apoptotic cells induces autoantibody production

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12 December 2020

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

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12 December 2020

Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus

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12 December 2020

Anti-phospholipid autoantibodies bind to apoptotic, but not viable, thymocytes in a beta 2-glycoprotein I-dependent manner

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12 December 2020

Fas-mediated apoptosis

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12 December 2020

Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells

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12 December 2020

A matter of life and cell death

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12 December 2020

Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization

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12 December 2020

A novel polymorphism of FcgammaRIIIa (CD16) alters receptor function and predisposes to autoimmune disease

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12 December 2020

Programmed cell death in the nematode C. elegans.

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12 December 2020

Features of systemic lupus erythematosus in Dnase1-deficient mice

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12 December 2020

The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster

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12 December 2020

Toxic effects of SLE serum on normal monocytes in vitro: cell death induced by apoptosis related to complement dysfunction

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12 December 2020

Caspase-dependent proteolysis of integral and peripheral proteins of nuclear membranes and nuclear pore complex proteins during apoptosis

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12 December 2020

Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2

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12 December 2020

Cytokine regulation of apoptosis and Bcl-2 expression in lymphocytes of patients with systemic lupus erythematosus

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12 December 2020

Resting B cells from New Zealand Black mice demonstrate a defect in apoptosis induction following surface IgM ligation

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12 December 2020

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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12 December 2020

Serum Factors Causing Impaired Macrophage Function in Systemic Lupus Erythematosus

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12 December 2020

Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95

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12 December 2020

Mononuclear phagocyte system in SLE. II. A kinetic model of immune complex handling in systemic lupus erythematosus

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12 December 2020

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

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12 December 2020

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

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12 December 2020

Immunosuppressive effects of apoptotic cells

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12 December 2020

Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus

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12 December 2020

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

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12 December 2020

A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo

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12 December 2020

Homeostasis and self-tolerance in the immune system: turning lymphocytes off.

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12 December 2020

Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

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12 December 2020

Caspase-3-Generated Fragment of Gelsolin: Effector of Morphological Change in Apoptosis

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12 December 2020

Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis.

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12 December 2020

Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP)

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12 December 2020

The TNF and TNF receptor superfamilies: integrating mammalian biology

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12 December 2020

Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis

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12 December 2020

Salmonella-induced apoptosis of infected macrophages results in presentation of a bacteria-encoded antigen after uptake by bystander dendritic cells

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12 December 2020

A death-domain-containing receptor that mediates apoptosis

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12 December 2020

High levels of bcl-2 protein in circulating T lymphocytes, but not B lymphocytes, of patients with systemic lupus erythematosus

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12 December 2020

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

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12 December 2020

Complement-dependent clearance of apoptotic cells by human macrophages

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12 December 2020

Functional loss of ABCA1 in mice causes severe placental malformation, aberrant lipid distribution, and kidney glomerulonephritis as well as high-density lipoprotein cholesterol deficiency

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12 December 2020

Cell Death in Development

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12 December 2020

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

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12 December 2020

Production of proinflammatory cytokines by phorbol myristate acetate-treated THP-1 cells and monocyte-derived macrophages after phagocytosis of apoptotic CTLL-2 cells.

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12 December 2020

Triggering caspase-independent cell death to combat cancer.

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12 December 2020

Complement activation by apoptotic endothelial cells following hypoxia/reoxygenation

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12 December 2020

Random locomotion and phagocytosis of monocytes in undiluted normal serum and in undiluted SLE serum

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12 December 2020

Human CED-6 encodes a functional homologue of the Caenorhabditis elegans engulfment protein CED-6

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12 December 2020

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

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12 December 2020

Targeting death and decoy receptors of the tumour-necrosis factor superfamily

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12 December 2020

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

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12 December 2020

Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans.

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12 December 2020

The apoptotic ligands TRAIL, TWEAK, and Fas ligand mediate monocyte death induced by autologous lupus T cells

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12 December 2020

Differential role for IL-2 and IL-15 in the inhibition of apoptosis in short-term activated human lymphocytes

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12 December 2020

A common set of engulfment genes mediates removal of both apoptotic and necrotic cell corpses in C. elegans

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12 December 2020

Characterization of two receptors for TRAIL1

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12 December 2020

A novel receptor for Apo2L/TRAIL contains a truncated death domain

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12 December 2020

Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans

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12 December 2020

C-Reactive protein binds to apoptotic cells, protects the cells from assembly of the terminal complement components, and sustains an antiinflammatory innate immune response: implications for systemic autoimmunity

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12 December 2020

Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes

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12 December 2020

The apoptosis-1/Fas protein in human systemic lupus erythematosus

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12 December 2020

Complement binding is an early feature of necrotic and a rather late event during apoptotic cell death

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12 December 2020

I-PLA(2) activation during apoptosis promotes the exposure of membrane lysophosphatidylcholine leading to binding by natural immunoglobulin M antibodies and complement activation

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12 December 2020

Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signaling

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12 December 2020

Corpse clearance defines the meaning of cell death

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12 December 2020

The spontaneous apoptotic cell death of normal human lymphocytes in vitro: the release of, and immunoproliferative response to, nucleosomes in vitro

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12 December 2020

Endogenous circulating DNA in systemic lupus erythematosus. Occurrence as multimeric complexes bound to histone

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12 December 2020

Death Receptor 5, a New Member of the TNFR Family, and DR4 Induce FADD-Dependent Apoptosis and Activate the NF-κB Pathway

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12 December 2020

The selective engulfment of apoptotic bodies by dendritic cells is mediated by the alpha(v)beta3 integrin and requires intracellular and extracellular calcium

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12 December 2020

TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)

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12 December 2020

Caspase structure, proteolytic substrates, and function during apoptotic cell death

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12 December 2020

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

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12 December 2020

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

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12 December 2020

How the worm removes corpses: the nematode C. elegans as a model system to study engulfment.

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12 December 2020

The Bcl2 family: regulators of the cellular life-or-death switch

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12 December 2020

Identification and characterization of a new member of the TNF family that induces apoptosis

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12 December 2020

Tumor-specific killer cells in paraneoplastic cerebellar degeneration

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12 December 2020

The C. elegans cell corpse engulfment gene ced-7 encodes a protein similar to ABC transporters.

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12 December 2020

Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease

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12 December 2020

A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes

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12 December 2020

Dendritic cells and the control of immunity

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12 December 2020

Activation of the alternative pathway of human complement by apoptotic human umbilical vein endothelial cells

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12 December 2020

T-cell apoptosis detected in situ during positive and negative selection in the thymus

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12 December 2020

Selection of the T cell repertoire.

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12 December 2020

Apoptotic DNA fragmentation

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12 December 2020

Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest

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12 December 2020

An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL

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12 December 2020

Regulation of macrophage cytokine production by phagocytosis of apoptotic and post-apoptotic cells

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12 December 2020

C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180

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12 December 2020

CD95's deadly mission in the immune system

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12 December 2020

Fas ligand expression and function in systemic lupus erythematosus

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12 December 2020

Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule

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12 December 2020

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

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12 December 2020

Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity

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12 December 2020

Homologous complement activation on drug-induced apoptotic cells from a human lung adenocarcinoma cell line.

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12 December 2020

Human T cells require IL-2 but not G1/S transition to acquire susceptibility to Fas-mediated apoptosis

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12 December 2020

Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene

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12 December 2020

Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases

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12 December 2020

Mechanisms and genes of cellular suicide

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12 December 2020

Mitochondria, the killer organelles and their weapons

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12 December 2020

CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans

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12 December 2020

Defective mononuclear phagocyte function in systemic lupus erythematosus: dissociation of Fc receptor-ligand binding and internalization

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12 December 2020

Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans

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12 December 2020

Dendritic cells capture killed tumor cells and present their antigens to elicit tumor-specific immune responses

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12 December 2020

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

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12 December 2020

Defective reticuloendothelial system Fc-receptor function in systemic lupus erythematosus

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12 December 2020

Mononuclear phagocyte system dysfunction in murine SLE: abnormal clearance kinetics precede clinical disease

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12 December 2020

Homozygous hereditary C1q deficiency and systemic lupus erythematosus. A new family and the molecular basis of C1q deficiency in three families

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12 December 2020

Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes

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12 December 2020

Identifiers

DOI

10.1385/CRIAI:25:1:49

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Dimensions Publication ID

6 August 2017

1013204146

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