Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95 (Q24314819)

GOA release 2020-03-11

signal transduction

1 reference

GOA release 2020-03-11

author name string

A M Chinnaiyan

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K O'Rourke

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G L Yu

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R H Lyons

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M Garg

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D R Duan

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L Xing

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R Gentz

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J Ni

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V M Dixit

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

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language of work or name

English

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publication date

8 November 1996

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published in

Science

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volume

274

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issue

5289

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page(s)

990-2

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cites work

1 reference

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7 January 2021

Contenders in FasL/TNF death signaling

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The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

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FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

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RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

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Homology between reaper and the cell death domains of Fas and TNFR1

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Identification and characterization of a new member of the TNF family that induces apoptosis

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TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

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https://api.crossref.org/works/10.1126%2FSCIENCE.274.5289.990

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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

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Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA.

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Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

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A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

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Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product

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Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway

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Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

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FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

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A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins

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TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

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Mechanisms and genes of cellular suicide

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Genetic control of programmed cell death in Drosophila

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