Novel age-dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research. (Q35101132)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19720431%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Novel age-dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research (English)

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6 February 2020

0 references

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6 February 2020

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6 February 2020

K S Montgomery

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6 February 2020

R K Simmons

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6 February 2020

M M Nicolle

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6 February 2020

M A Gluck

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6 February 2020

J L Bizon

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publication date

31 August 2009

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6 February 2020

published in

Neurobiology of Aging

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6 February 2020

volume

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issue

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6 February 2020

page(s)

1273-1285

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Double dissociation of the effects of medial and orbital prefrontal cortical lesions on attentional and affective shifts in mice.

6 February 2020

cites work

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The medial temporal lobe

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Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

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Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice

9 July 2018

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9 July 2018

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

9 July 2018

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Cholinergic system regulation of spatial representation by the hippocampus

9 July 2018

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Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

9 July 2018

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Conjunctive representations in learning and memory: principles of cortical and hippocampal function.

9 July 2018

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Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice

9 July 2018

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Pathogenic mechanisms of Alzheimer's disease analyzed in the APP23 transgenic mouse model

9 July 2018

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Medial frontal cortex mediates perceptual attentional set shifting in the rat.

9 July 2018

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Neuropsychological prediction of decline to dementia in nondemented elderly

9 July 2018

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Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies

9 July 2018

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The incidence of dementia: a meta-analysis

9 July 2018

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Cortico-hippocampal representations in simultaneous odor discrimination: a computational interpretation of Eichenbaum, Mathews, and Cohen (1989).

9 July 2018

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Configural association theory and the hippocampal formation: an appraisal and reconfiguration

9 July 2018

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Conservation of hippocampal memory function in rats and humans

9 July 2018

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Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze

9 July 2018

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Hippocampal mediation of stimulus representation: a computational theory

9 July 2018

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Place navigation impaired in rats with hippocampal lesions

9 July 2018

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Further studies of hippocampal representation during odor discrimination learning.

9 July 2018

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Change in background context disrupts performance on visual paired comparison following hippocampal damage.

9 July 2018

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Learning and generalization deficits in patients with memory impairments due to anterior communicating artery aneurysm rupture or hypoxic brain injury

27 September 2018

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Perirhinal cortex supports encoding and familiarity-based recognition of novel associations

27 September 2018

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An increase in Abeta42 in the prefrontal cortex is associated with a reversal-learning impairment in Alzheimer's disease model Tg2576 APPsw mice.

27 September 2018

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Learning and generalization tasks predict short-term cognitive outcome in nondemented elderly

27 September 2018

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Chronic, low-dose prenatal exposure to methylmercury impairs motor and mnemonic function in adult C57/B6 mice

27 September 2018

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Effects of the genetic background on cognitive performances of TG2576 mice

27 September 2018

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Impaired spatial learning in the APPSwe + PSEN1DeltaE9 bigenic mouse model of Alzheimer's disease.

27 September 2018

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Olfaction in patients with mild cognitive impairment and Alzheimer's disease.

27 September 2018

1 reference

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Effect of unitization on associative recognition in amnesia

27 September 2018

1 reference

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Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer's disease mouse models with abundant A beta in plasma.

27 September 2018

1 reference

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Early discrimination reversal learning impairment and preserved spatial learning in a longitudinal study of Tg2576 APPsw mice.

27 September 2018

1 reference

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Deficits across multiple cognitive domains in a subset of aged Fischer 344 rats.

27 September 2018

1 reference

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Intact spatial learning in adult Tg2576 mice.

27 September 2018

1 reference

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A comparison and evaluation of the predictions of relational and conjunctive accounts of hippocampal function

27 September 2018

1 reference

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Functional specialization in the human medial temporal lobe.

27 September 2018

1 reference

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Estrogen therapy fails to alter amyloid deposition in the PDAPP model of Alzheimer's disease

27 September 2018

1 reference

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The role of the hippocampus in the retrieval of a spatial location.

27 September 2018

1 reference

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Spatial learning and exploration of environmental stimuli in 24-month-old female APP23 transgenic mice with the Swedish mutation

27 September 2018

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Relational integration and executive function in Alzheimer's disease.

27 September 2018

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Estrogen treatment improves spatial learning in APP + PS1 mice but does not affect beta amyloid accumulation and plaque formation

27 September 2018

1 reference

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Orbital prefrontal cortex mediates reversal learning and not attentional set shifting in the rat.

27 September 2018

1 reference

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Effects of fimbria-fornix lesion and amyloid pathology on spatial learning and memory in transgenic APP+PS1 mice

27 September 2018

1 reference

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Aged rats are impaired on an attentional set-shifting task sensitive to medial frontal cortex damage in young rats.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334376

Hippocampal atrophy disrupts transfer generalization in nondemented elderly

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334376

Orbitofrontal lesions in rats impair reversal but not acquisition of go, no-go odor discriminations

27 September 2018

1 reference

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Hippocampal A beta 42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice

27 September 2018

1 reference

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Executive deficits appearing in the initial stage of Alzheimer's disease.

27 September 2018

1 reference

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Correlation between cognitive deficits and Abeta deposits in transgenic APP+PS1 mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334376

Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

27 September 2018

1 reference

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Time estimation in schizophrenia: an fMRI study at adjusted levels of difficulty

27 September 2018

1 reference

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Excitotoxic hippocampal lesions disrupt allocentric spatial learning in mice: effects of strain and task demands.

27 September 2018

1 reference

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Memory deficits for implicit contextual information in amnesic subjects with hippocampal damage

27 September 2018

1 reference

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The radiologic prediction of Alzheimer disease: the atrophic hippocampal formation.

27 September 2018

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10.1016/J.NEUROBIOLAGING.2009.08.003

27 September 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19720431%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19720431%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

19720431

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19720431%20AND%20SRC:MED&resulttype=core&format=json