Novel age-dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research. (Q35101132)

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English	Novel age-dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research.	scientific article

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scholarly article

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6 February 2020

Novel age-dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research (English)

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6 February 2020

Alzheimer's disease

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George Edwards III

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6 February 2020

Catherine E Myers

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6 February 2020

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K S Montgomery

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6 February 2020

R K Simmons

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6 February 2020

M M Nicolle

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6 February 2020

M A Gluck

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6 February 2020

J L Bizon

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6 February 2020

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31 August 2009

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6 February 2020

Neurobiology of Aging

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6 February 2020

32

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6 February 2020

7

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6 February 2020

1273-1285

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6 February 2020

Double dissociation of the effects of medial and orbital prefrontal cortical lesions on attentional and affective shifts in mice.

1 reference

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9 July 2018

Discriminating accuracy of medial temporal lobe volumetry and fMRI in mild cognitive impairment

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9 July 2018

Recall and recognition of verbal paired associates in early Alzheimer's disease

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9 July 2018

Spatial reference and working memory across the lifespan of male Fischer 344 rats

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9 July 2018

Associative learning over trials activates the hippocampus in healthy elderly but not mild cognitive impairment

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9 July 2018

Structural learning and the hippocampus

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9 July 2018

The medial temporal lobe and recognition memory

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9 July 2018

Computational models of the hippocampal region: implications for prediction of risk for Alzheimer's disease in non-demented elderly.

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9 July 2018

Encoding changes in orbitofrontal cortex in reversal-impaired aged rats

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9 July 2018

The medial temporal lobe

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9 July 2018

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

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9 July 2018

Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice

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9 July 2018

Effects of aging on the hippocampal formation in a naturally occurring animal model of mild cognitive impairment

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9 July 2018

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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9 July 2018

Cholinergic system regulation of spatial representation by the hippocampus

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9 July 2018

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

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9 July 2018

Conjunctive representations in learning and memory: principles of cortical and hippocampal function.

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9 July 2018

Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice

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9 July 2018

Pathogenic mechanisms of Alzheimer's disease analyzed in the APP23 transgenic mouse model

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9 July 2018

Medial frontal cortex mediates perceptual attentional set shifting in the rat.

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9 July 2018

Neuropsychological prediction of decline to dementia in nondemented elderly

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9 July 2018

Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies

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9 July 2018

Cortico-hippocampal representations in simultaneous odor discrimination: a computational interpretation of Eichenbaum, Mathews, and Cohen (1989).

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9 July 2018

Configural association theory and the hippocampal formation: an appraisal and reconfiguration

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9 July 2018

Conservation of hippocampal memory function in rats and humans

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9 July 2018

Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze

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9 July 2018

Hippocampal mediation of stimulus representation: a computational theory

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9 July 2018

Place navigation impaired in rats with hippocampal lesions

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9 July 2018

Further studies of hippocampal representation during odor discrimination learning.

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9 July 2018

Change in background context disrupts performance on visual paired comparison following hippocampal damage.

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27 September 2018

Learning and generalization deficits in patients with memory impairments due to anterior communicating artery aneurysm rupture or hypoxic brain injury

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27 September 2018

Perirhinal cortex supports encoding and familiarity-based recognition of novel associations

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27 September 2018

An increase in Abeta42 in the prefrontal cortex is associated with a reversal-learning impairment in Alzheimer's disease model Tg2576 APPsw mice.

1 reference

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27 September 2018

Learning and generalization tasks predict short-term cognitive outcome in nondemented elderly

1 reference

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27 September 2018

Chronic, low-dose prenatal exposure to methylmercury impairs motor and mnemonic function in adult C57/B6 mice

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27 September 2018

Effects of the genetic background on cognitive performances of TG2576 mice

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27 September 2018

Impaired spatial learning in the APPSwe + PSEN1DeltaE9 bigenic mouse model of Alzheimer's disease.

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27 September 2018

Olfaction in patients with mild cognitive impairment and Alzheimer's disease.

1 reference

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27 September 2018

Effect of unitization on associative recognition in amnesia

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27 September 2018

Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer's disease mouse models with abundant A beta in plasma.

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27 September 2018

Early discrimination reversal learning impairment and preserved spatial learning in a longitudinal study of Tg2576 APPsw mice.

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27 September 2018

Deficits across multiple cognitive domains in a subset of aged Fischer 344 rats.

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27 September 2018

Intact spatial learning in adult Tg2576 mice.

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27 September 2018

A comparison and evaluation of the predictions of relational and conjunctive accounts of hippocampal function

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27 September 2018

Functional specialization in the human medial temporal lobe.

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27 September 2018

Estrogen therapy fails to alter amyloid deposition in the PDAPP model of Alzheimer's disease

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27 September 2018

Spatial learning and exploration of environmental stimuli in 24-month-old female APP23 transgenic mice with the Swedish mutation

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27 September 2018

Relational integration and executive function in Alzheimer's disease.

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27 September 2018

Estrogen treatment improves spatial learning in APP + PS1 mice but does not affect beta amyloid accumulation and plaque formation

1 reference

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Orbital prefrontal cortex mediates reversal learning and not attentional set shifting in the rat.

1 reference

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Effects of fimbria-fornix lesion and amyloid pathology on spatial learning and memory in transgenic APP+PS1 mice

1 reference

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27 September 2018

Aged rats are impaired on an attentional set-shifting task sensitive to medial frontal cortex damage in young rats.

1 reference

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27 September 2018

Hippocampal atrophy disrupts transfer generalization in nondemented elderly

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1 reference

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Executive deficits appearing in the initial stage of Alzheimer's disease.

1 reference

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27 September 2018

Correlation between cognitive deficits and Abeta deposits in transgenic APP+PS1 mice

1 reference

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Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

1 reference

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27 September 2018

Excitotoxic hippocampal lesions disrupt allocentric spatial learning in mice: effects of strain and task demands.

1 reference

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27 September 2018

Memory deficits for implicit contextual information in amnesic subjects with hippocampal damage

1 reference

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The radiologic prediction of Alzheimer disease: the atrophic hippocampal formation.

1 reference

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27 September 2018

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10.1016/J.NEUROBIOLAGING.2009.08.003

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6 February 2020

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Europe PubMed Central

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6 February 2020

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Europe PubMed Central

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6 February 2020

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