Naringin directly activates inwardly rectifying potassium channels at an overlapping binding site to tertiapin-Q. (Q35089876)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21391982%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Naringin directly activates inwardly rectifying potassium channels at an overlapping binding site to tertiapin-Q (English)

1 reference

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25 January 2020

1 reference

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25 January 2020

Tin T Yow

1 reference

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25 January 2020

Nathan Absalom

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21391982%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Marika Heblinski

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21391982%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Graham A R Johnston

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21391982%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Jane R Hanrahan

1 reference

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25 January 2020

Mary Chebib

1 reference

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25 January 2020

language of work or name

English

0 references

publication date

1 July 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21391982%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Pharmacology

25 January 2020

published in

1 reference

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25 January 2020

volume

163

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25 January 2020

issue

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25 January 2020

page(s)

1017-1033

1 reference

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Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease.

25 January 2020

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Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner

8 July 2018

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The dietary flavonoids apigenin and (-)-epigallocatechin gallate enhance the positive modulation by diazepam of the activation by GABA of recombinant GABA(A) receptors

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Inhibition of G protein-activated inwardly rectifying K+ channels by fluoxetine (Prozac).

8 July 2018

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Structural basis of inward rectification: cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 A resolution

8 July 2018

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Gating properties of GIRK channels activated by Galpha(o)- and Galpha(i)-coupled muscarinic m2 receptors in Xenopus oocytes: the role of receptor precoupling in RGS modulation.

8 July 2018

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Functional characterization of an endogenous Xenopus oocyte adenosine receptor

8 July 2018

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Dietary agents in cancer prevention: flavonoids and isoflavonoids.

8 July 2018

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G protein-gated inwardly rectifying potassium channels are targets for volatile anesthetics.

8 July 2018

1 reference

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Mechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying K+ channels

8 July 2018

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G-protein mediated gating of inward-rectifier K+ channels

8 July 2018

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Inhibition by various antipsychotic drugs of the G-protein-activated inwardly rectifying K(+) (GIRK) channels expressed in xenopus oocytes

8 July 2018

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Mass spectrometric identification and high-performance liquid chromatographic determination of a flavonoid glycoside naringin in human urine

8 July 2018

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Mechanisms of inward-rectifier K+ channel inhibition by tertiapin-Q.

8 July 2018

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Ethanol opens G-protein-activated inwardly rectifying K+ channels

8 July 2018

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G-protein-coupled inwardly rectifying potassium channels are targets of alcohol action

8 July 2018

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Gating of G protein-sensitive inwardly rectifying K+ channels through phosphatidylinositol 4,5-bisphosphate

8 July 2018

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8 July 2018

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8 July 2018

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Identification of native atrial G-protein-regulated inwardly rectifying K+ (GIRK4) channel homomultimers

8 July 2018

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The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

8 July 2018

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8 July 2018

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Signalling Via the G Protein-Activated K+ Channels

8 July 2018

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8 July 2018

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Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2

8 July 2018

1 reference

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Comparison of the three mouse G-protein-activated K+ (GIRK) channels and functional couplings of the opioid receptors with the GIRK1 channel

8 July 2018

1 reference

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Control of channel activity through a unique amino acid residue of a G protein-gated inwardly rectifying K+ channel subunit

8 July 2018

1 reference

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Xenopus oocytes express multiple receptors for LPA-like lipid mediators

8 July 2018

1 reference

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Mutations in the K+ channel signature sequence

8 July 2018

1 reference

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Cloning provides evidence for a family of inward rectifier and G-protein coupled K+ channels in the brain

8 July 2018

1 reference

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Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study

8 July 2018

1 reference

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Molecular cloning of a mouse G-protein-activated K+ channel (mGIRK1) and distinct distributions of three GIRK (GIRK1, 2 and 3) mRNAs in mouse brain

8 July 2018

1 reference

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Kappa-opioid receptors couple to inwardly rectifying potassium channels when coexpressed by Xenopus oocytes

8 July 2018

1 reference

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Molecular properties of neuronal G-protein-activated inwardly rectifying K+ channels.

8 July 2018

1 reference

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Activation of red cell Ca2(+)-activated K+ channel by Ca2+ involves a temperature-dependent step.

8 July 2018

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Antiproliferative effects of citrus flavonoids on a human squamous cell carcinoma in vitro

8 July 2018

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The aromatic binding site for tetraethylammonium ion on potassium channels

8 July 2018

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Wine, alcohol, platelets, and the French paradox for coronary heart disease

8 July 2018

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A Functional Connection Between the Pores of Distantly Related Ion Channels as Revealed by Mutant K + Channels

8 July 2018

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Central nervous system depressant action of flavonoid glycosides.

8 July 2018

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The flavonoid glycosides, myricitrin, gossypin and naringin exert anxiolytic action in mice.

21 January 2018

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6-Methylflavanone, a more efficacious positive allosteric modulator of gamma-aminobutyric acid (GABA) action at human recombinant alpha2beta2gamma2L than at alpha1beta2gamma2L and alpha1beta2 GABA(A) receptors expressed in Xenopus oocytes.

21 January 2018

1 reference

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Mutational analysis of ethanol interactions with G-protein-coupled inwardly rectifying potassium channels

21 January 2018

1 reference

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Functional couplings of the delta- and the kappa-opioid receptors with the G-protein-activated K+ channel

21 January 2018

1 reference

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Functional coupling of the nociceptin/orphanin FQ receptor with the G-protein-activated K+ (GIRK) channel

21 January 2018

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G protein-activated K+ channels: a reporter for rapid activation of G proteins by lysophosphatidic acid in Xenopus oocytes

21 January 2018

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A novel high-affinity inhibitor for inward-rectifier K+ channels

21 January 2018

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G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons

21 January 2018

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Analysis of the antinociceptive effect of the flavonoid myricitrin: evidence for a role of the L-arginine-nitric oxide and protein kinase C pathways

21 January 2018

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The sensitivity of G protein-activated K+ channels toward halothane is essentially determined by the C terminus

21 January 2018

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Short variable sequence acquired in evolution enables selective inhibition of various inward-rectifier K+ channels

21 January 2018

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Molecular mechanisms of the naringin low uptake by intestinal Caco-2 cells

21 January 2018

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Determination of naringin in rat blood, brain, liver, and bile using microdialysis and its interaction with cyclosporin a, a p-glycoprotein modulator

21 January 2018

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The dual modulation of GIRK1/GIRK2 channels by opioid receptor ligands

21 January 2018

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Gossypin-induced analgesia in mice

21 January 2018

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Abnormal heart rate regulation in GIRK4 knockout mice.

21 January 2018

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Differential effects of general anesthetics on G protein-coupled inwardly rectifying and other potassium channels

21 January 2018

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Guide to Receptors and Channels (GRAC), 4th Edition

21 January 2018

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Identification of G protein-coupled, inward rectifier potassium channel gene products from the rat anterior pituitary gland

27 September 2018

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Flavonoid Intake and Long-term Risk of Coronary Heart Disease and Cancer in the Seven Countries Study

27 September 2018

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Anti-allodynic property of flavonoid myricitrin in models of persistent inflammatory and neuropathic pain in mice

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Antinociceptive action of myricitrin: involvement of the K+ and Ca2+ channels

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Timing is everything the role of kinetics in G protein activation

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Determination of Flavonoids in Plant Material by HPLC with Diode-Array and Electro-Array Detections

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21391982%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21391982%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

21391982

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21391982%20AND%20SRC:MED&resulttype=core&format=json