Somatic mutations, viral integration and epigenetic modification in the evolution of hepatitis B virus-induced hepatocellular carcinoma (Q35029955)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646075%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Somatic mutations, viral integration and epigenetic modification in the evolution of hepatitis B virus-induced hepatocellular carcinoma (English)

1 reference

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29 February 2020

1 reference

hepatocellular carcinoma

1 reference

1 reference

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29 February 2020

Xiaowei Ji

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646075%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Qi Zhang

1 reference

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29 February 2020

Wenbin Liu

1 reference

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29 February 2020

Zixiong Li

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646075%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Xiaomei Hou

1 reference

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29 February 2020

Guangwen Cao

1 reference

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29 February 2020

publication date

1 December 2014

1 reference

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29 February 2020

1 reference

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29 February 2020

volume

1 reference

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29 February 2020

issue

1 reference

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29 February 2020

page(s)

469-480

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646075%20AND%20SRC:MED&resulttype=core&format=json

Mother-to-child transmission of hepatitis B virus: evolution of hepatocellular carcinoma-related viral mutations in the post-immunization era.

29 February 2020

cites work

1 reference

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HLA-DP polymorphisms affect the outcomes of chronic hepatitis B virus infections, possibly through interacting with viral mutations

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Exome capture sequencing reveals new insights into hepatitis B virus-induced hepatocellular carcinoma at the early stage of tumorigenesis

8 July 2018

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Hepatitis B virus surface antigen (HBsAg) mutations are rare but clustered in immune epitopes in chronic carriers from Sistan-Balouchestan Province, Iran

8 July 2018

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Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma

8 July 2018

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A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma

8 July 2018

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Hepatitis B virus X protein-induced aberrant epigenetic modifications contributing to human hepatocellular carcinoma pathogenesis

8 July 2018

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Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis

8 July 2018

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Endogenous retrotransposition activates oncogenic pathways in hepatocellular carcinoma

8 July 2018

1 reference

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Genome-wide analysis of miRNA signature differentially expressed in doxorubicin-resistant and parental human hepatocellular carcinoma cell lines

8 July 2018

1 reference

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HBV core promoter mutations promote cellular proliferation through E2F1-mediated upregulation of S-phase kinase-associated protein 2 transcription.

8 July 2018

1 reference

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RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase

8 July 2018

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Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma

8 July 2018

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Deep sequencing of the hepatitis B virus in hepatocellular carcinoma patients reveals enriched integration events, structural alterations and sequence variations

8 July 2018

1 reference

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Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach

8 July 2018

1 reference

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Human hepatocellular carcinoma cell-specific miRNAs reveal the differential expression of miR-24 and miR-27a in cirrhotic/non-cirrhotic HCC

8 July 2018

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Hepatitis B virus DNA integration in tumour tissue of a non-cirrhotic HFE-haemochromatosis patient with hepatocellular carcinoma.

8 July 2018

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Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma

8 July 2018

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Association of polymorphism in pri-microRNAs-371-372-373 with the occurrence of hepatocellular carcinoma in hepatitis B virus infected patients.

8 July 2018

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C-terminal truncated hepatitis B virus x protein is associated with metastasis and enhances invasiveness by C-Jun/matrix metalloproteinase protein 10 activation in hepatocellular carcinoma.

8 July 2018

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Involvement of hepatitis B virus X gene (HBx) integration in hepatocarcinogenesis via a recombination of HBx/Alu core sequence/subtelomeric DNA.

8 July 2018

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Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

8 July 2018

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Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

8 July 2018

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8 July 2018

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8 July 2018

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Akt augments the oncogenic potential of the HBx protein of hepatitis B virus by phosphorylation

8 July 2018

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The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients.

8 July 2018

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Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

8 July 2018

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Inhibition of PP1 phosphatase activity by HBx: a mechanism for the activation of hepatitis B virus transcription

8 July 2018

1 reference

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Genomics of AML: clinical applications of next-generation sequencing

8 July 2018

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ARID2: a new tumor suppressor gene in hepatocellular carcinoma

8 July 2018

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Hypomethylation of the hsa-miR-191 locus causes high expression of hsa-mir-191 and promotes the epithelial-to-mesenchymal transition in hepatocellular carcinoma

8 July 2018

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MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma.

8 July 2018

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Carboxyl-terminal truncated HBx regulates a distinct microRNA transcription program in hepatocellular carcinoma development

8 July 2018

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Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma

8 July 2018

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Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data

8 July 2018

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Hepatitis B virus core promoter mutations contribute to hepatocarcinogenesis by deregulating SKP2 and its target, p21

8 July 2018

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Role of microRNAs in hepatitis B virus replication and pathogenesis.

8 July 2018

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High-resolution characterization of a hepatocellular carcinoma genome

8 July 2018

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Paired Box Gene 5 Is a Novel Tumor Suppressor in Hepatocellular Carcinoma Through Interaction With p53 Signaling Pathway §Δ

8 July 2018

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Global cancer statistics

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Sequencing and Bioinformatics-Based Analyses of the microRNA Transcriptome in Hepatitis B–Related Hepatocellular Carcinoma

8 July 2018

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Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBV-positive hepatocarcinoma

8 July 2018

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The C-terminal region of the hepatitis B virus X protein is essential for its stability and function

8 July 2018

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A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response

8 July 2018

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8 July 2018

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Long antisense non-coding RNAs and their role in transcription and oncogenesis

8 July 2018

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Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis

8 July 2018

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Clonal expansion of normal-appearing human hepatocytes during chronic hepatitis B virus infection

8 July 2018

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Clinical relevance and public health significance of hepatitis B virus genomic variations

8 July 2018

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Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function.

8 July 2018

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Human APOBEC1 cytidine deaminase edits HBV DNA

8 July 2018

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HBV A1762T, G1764A mutations are a valuable biomarker for identifying a subset of male HBsAg carriers at extremely high risk of hepatocellular carcinoma: a prospective study

8 July 2018

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Risk factors for acute hepatitis B and its progression to chronic hepatitis in Shanghai, China

8 July 2018

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COOH-terminal truncated HBV X protein plays key role in hepatocarcinogenesis

8 July 2018

1 reference

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Associations between hepatitis B virus genotype and mutants and the risk of hepatocellular carcinoma

8 July 2018

1 reference

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Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells

8 July 2018

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Mutations in the C-terminus of the X protein of hepatitis B virus regulate Wnt-5a expression in hepatoma Huh7 cells: cDNA microarray and proteomic analyses

8 July 2018

1 reference

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Integration of hepatitis B virus DNA into the myeloid/lymphoid or mixed-lineage leukemia (MLL4) gene and rearrangements of MLL4 in human hepatocellular carcinoma

8 July 2018

1 reference

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Hepatocellular carcinoma pathogenesis: from genes to environment

8 July 2018

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The tumor microenvironment in the post-PAGET era.

8 July 2018

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The global health burden of infection-associated cancers in the year 2002

8 July 2018

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Epigenetic differences arise during the lifetime of monozygotic twins

8 July 2018

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Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas

8 July 2018

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Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo

8 July 2018

1 reference

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Aberrant DNA methylation as a cancer-inducing mechanism

8 July 2018

1 reference

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DNA methylation and cancer therapy: new developments and expectations

8 July 2018

1 reference

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Biological impact of natural COOH-terminal deletions of hepatitis B virus X protein in hepatocellular carcinoma tissues.

8 July 2018

1 reference

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Hepatitis B virus X mutants derived from human hepatocellular carcinoma retain the ability to abrogate p53-induced apoptosis

8 July 2018

1 reference

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Deep sequencing of small RNA transcriptome reveals novel non-coding RNAs in hepatocellular carcinoma

8 July 2018

1 reference

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C-terminal region of HBx is crucial for mitochondrial DNA damage

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4311391

Hepatitis B virus X protein (HBx)-related long noncoding RNA (lncRNA) down-regulated expression by HBx (Dreh) inhibits hepatocellular carcinoma metastasis by targeting the intermediate filament protein vimentin

25 October 2018

1 reference

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Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma

25 October 2018

1 reference

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Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection.

25 October 2018

1 reference

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Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression

25 October 2018

1 reference

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Characterization of HBV integrants in 14 hepatocellular carcinomas: association of truncated X gene and hepatocellular carcinogenesis.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4311391

Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4311391

A meta-analysis of epidemiological studies on the combined effect of hepatitis B and C virus infections in causing hepatocellular carcinoma

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4311391

Integration of hepatitis B virus DNA into the genome of liver cells in chronic liver disease and hepatocellular carcinoma. Studies in percutaneous liver biopsies and post-mortem tissue specimens

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4311391

A long noncoding RNA activated by TGF-β promotes the invasion-metastasis cascade in hepatocellular carcinoma

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25646075

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Assessing tumor heterogeneity and emergence mutations using next-generation sequencing for overcoming cancer drugs resistance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25646075

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2174/1389202915666141114213833

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646075%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646075%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

25646075

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25646075%20AND%20SRC:MED&resulttype=core&format=json