Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function. (Q37418293)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906987%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function (English)

1 reference

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12 February 2020

1 reference

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12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906987%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906987%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Laura Belloni

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906987%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Francesca De Nicola

1 reference

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12 February 2020

Giuseppina Raffa

1 reference

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12 February 2020

Maurizio Fanciulli

1 reference

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12 February 2020

Giovanni Raimondo

1 reference

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12 February 2020

language of work or name

English

0 references

publication date

11 November 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906987%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

12 February 2020

published in

1 reference

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12 February 2020

volume

106

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issue

1 reference

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12 February 2020

page(s)

19975-19979

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906987%20AND%20SRC:MED&resulttype=core&format=json

Control of cccDNA function in hepatitis B virus infection.

12 February 2020

cites work

1 reference

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Hepatitis B virus HBx protein localized to the nucleus restores HBx-deficient virus replication in HepG2 cells and in vivo in hydrodynamically-injected mice

6 September 2017

1 reference

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Enhancement of hepatitis B virus replication by the regulatory X protein in vitro and in vivo

6 September 2017

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Molecular functions and biological roles of hepatitis B virus x protein

6 September 2017

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6 September 2017

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6 September 2017

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The transcriptional transactivation function of HBx protein is important for its augmentation role in hepatitis B virus replication

6 September 2017

1 reference

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Hepatitis B virus X protein stimulates viral genome replication via a DDB1-dependent pathway distinct from that leading to cell death

6 September 2017

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6 September 2017

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X-deficient woodchuck hepatitis virus mutants behave like attenuated viruses and induce protective immunity in vivo

6 September 2017

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6 September 2017

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6 September 2017

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Mapping chromosomal proteins in vivo by formaldehyde-crosslinked-chromatin immunoprecipitation

6 September 2017

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The hepatitis B virus X gene induces p53-mediated programmed cell death

6 September 2017

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The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks.

6 September 2017

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Woodchuck hepatitis virus X protein is required for viral infection in vivo

6 September 2017

1 reference

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The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes.

6 September 2017

1 reference

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A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2775998

The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2775998

Hepatitis B virus. The major etiology of hepatocellular carcinoma

6 September 2017

1 reference

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Hepatitis B virus X protein is not central to the viral life cycle in vitro

6 September 2017

1 reference

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Hepatitis B virus X protein acts as a tumor promoter in development of diethylnitrosamine-induced preneoplastic lesions

6 September 2017

1 reference

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Epigenetic modification induced by hepatitis B virus X protein via interaction with de novo DNA methyltransferase DNMT3A.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2775998

Expression of DNA methyltransferase 1 is activated by hepatitis B virus X protein via a regulatory circuit involving the p16INK4a-cyclin D1-CDK 4/6-pRb-E2F1 pathway

14 September 2017

1 reference

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Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2775998

Hepatitis B virus DNA replication is coordinated by core protein serine phosphorylation and HBx expression

14 September 2017

1 reference

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Src kinases involved in hepatitis B virus replication

14 September 2017

1 reference

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Premature cell cycle entry induced by hepatitis B virus regulatory HBx protein during compensatory liver regeneration

28 September 2017

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The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice

26 June 2018

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Increased sensitivity to the hepatocarcinogen diethylnitrosamine in transgenic mice carrying the hepatitis B virus X gene

26 June 2018

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HBx gene of hepatitis B virus induces liver cancer in transgenic mice

26 June 2018

1 reference

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The hepatitis B virus X protein functionally interacts with CREB-binding protein/p300 in the regulation of CREB-mediated transcription.

26 June 2018

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Hepatitis B virus replication is regulated by the acetylation status of hepatitis B virus cccDNA-bound H3 and H4 histones

2 September 2018

1 reference

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Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy.

2 September 2018

1 reference

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Hepatitis B virus maintains its pro-oncogenic properties in the case of occult HBV infection.

2 September 2018

1 reference

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Calcium signaling by HBx protein in hepatitis B virus DNA replication

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2775998

Structural organization of the hepatitis B virus minichromosome

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2775998

Correct binding of viral X protein to UVDDB-p127 cellular protein is critical for efficient infection by hepatitis B viruses

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19906987

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0908365106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906987%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906987%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

19906987

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906987%20AND%20SRC:MED&resulttype=core&format=json