Challenges in the pursuit of immune tolerance. (Q34974448)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21488889%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

review article

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title

Challenges in the pursuit of immune tolerance (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21488889%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21488889%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

E William St Clair

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21488889%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Laurence A Turka

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28 January 2020

publication date

1 May 2011

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28 January 2020

published in

Immunological Reviews

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28 January 2020

volume

241

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28 January 2020

issue

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28 January 2020

page(s)

49-62

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21488889%20AND%20SRC:MED&resulttype=core&format=json

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells.

28 January 2020

cites work

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Allogeneic hematopoietic stem-cell transplantation for sickle cell disease

8 July 2018

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Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy

8 July 2018

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Anti-Neutrophil Cytoplasmic Antibody Pathogenesis in Small-Vessel Vasculitis

8 July 2018

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Epigenetic mechanisms of regulation of Foxp3 expression

8 July 2018

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Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb Teplizumab preserves insulin production for up to 5 years

8 July 2018

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Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects

8 July 2018

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The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells

8 July 2018

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Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression

8 July 2018

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Using transcriptional profiling to develop a diagnostic test of operational tolerance in liver transplant recipients

8 July 2018

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Antigen-specific therapies in MS - Current concepts and novel approaches.

8 July 2018

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Recurrence of autoreactive antigen-specific CD4+ T cells in autoimmune diabetes after pancreas transplantation.

8 July 2018

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B-cell depletion with rituximab in relapsing-remitting multiple sclerosis

8 July 2018

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HLA-mismatched renal transplantation without maintenance immunosuppression

8 July 2018

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Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice

8 July 2018

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Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance

8 July 2018

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Antigen-specific tolerance strategies for the prevention and treatment of autoimmune disease

8 July 2018

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8 July 2018

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CD3-specific antibodies: a portal to the treatment of autoimmunity

8 July 2018

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Multi-peptide coupled-cell tolerance ameliorates ongoing relapsing EAE associated with multiple pathogenic autoreactivities

8 July 2018

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Chimeric human fcgamma-allergen fusion proteins in the prevention of allergy

8 July 2018

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Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs

8 July 2018

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Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis.

8 July 2018

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Rituximab for refractory Wegener's granulomatosis: report of a prospective, open-label pilot trial

8 July 2018

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Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

8 July 2018

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A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes

8 July 2018

1 reference

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Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

8 July 2018

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De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25- cells

8 July 2018

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Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis

8 July 2018

1 reference

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CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.

8 July 2018

1 reference

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Actively acquired tolerance of foreign cells

8 July 2018

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Activation of human T cells by FcR nonbinding anti-CD3 mAb, hOKT3gamma1(Ala-Ala).

8 July 2018

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CD3-specific antibody-induced active tolerance: from bench to bedside

8 July 2018

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Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

8 July 2018

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Mixed chimerism and transplant tolerance

8 July 2018

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Biomarkers and surrogate endpoints: preferred definitions and conceptual framework

8 July 2018

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Mixed chimerism and tolerance without whole body irradiation in a large animal model

8 July 2018

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Mixed chimerism as an approach for the induction of transplantation tolerance

8 July 2018

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Humanized, nonmitogenic OKT3 antibody, huOKT3 gamma(Ala-Ala): initial clinical experience

8 July 2018

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Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy

8 July 2018

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Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

8 July 2018

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Anti-tumor necrosis factor modulates anti-CD3-triggered T cell cytokine gene expression in vivo

8 July 2018

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Human in vivo antigenic modulation induced by the anti-T cell OKT3 monoclonal antibody.

8 July 2018

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Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen

8 July 2018

1 reference

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TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes

8 July 2018

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Identification of two subpopulations of purified human blood B cells, CD27- CD23+ and CD27high CD80+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6.

21 January 2018

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Response of Wegener's granulomatosis to anti-CD20 chimeric monoclonal antibody therapy

21 January 2018

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Induction of remission by B lymphocyte depletion in eleven patients with refractory antineutrophil cytoplasmic antibody-associated vasculitis

21 January 2018

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Grass pollen immunotherapy: IL-10 induction and suppression of late responses precedes IgG4 inhibitory antibody activity

21 January 2018

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Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients

21 January 2018

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Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

21 January 2018

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Phase I trial of a humanized, Fc receptor nonbinding OKT3 antibody, huOKT3gamma1(Ala-Ala) in the treatment of acute renal allograft rejection

26 October 2018

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Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

26 October 2018

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Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts

21 January 2018

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Long-term outcome and alloantibody production in a non-myeloablative regimen for induction of renal allograft tolerance

21 January 2018

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12 December 2020

T cell activation in rheumatoid synovium is B cell dependent

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CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primates

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Effects of in vivo administration of anti-CD3 monoclonal antibody on T cell function in mice. II. In vivo activation of T cells

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Humanized OKT3 antibodies: successful transfer of immune modulating properties and idiotype expression

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Effect of a single amino acid mutation on the activating and immunosuppressive properties of a "humanized" OKT3 monoclonal antibody

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A non-activating "humanized" anti-CD3 monoclonal antibody retains immunosuppressive properties in vivo

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Mixed allogeneic chimerism and renal allograft tolerance in cynomolgus monkeys

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Compound heterozygosity of HLA-DR4 and DR1 antigens in Asian Indians increases the risk of extra-articular features in rheumatoid arthritis

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CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice

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Partial TCR signals delivered by FcR-nonbinding anti-CD3 monoclonal antibodies differentially regulate individual Th subsets

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Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis

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Combination treatment with omalizumab and rush immunotherapy for ragweed-induced allergic rhinitis: Inhibition of IgE-facilitated allergen binding

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10.1111/J.1600-065X.2011.01003.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21488889%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21488889%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

21488889

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21488889%20AND%20SRC:MED&resulttype=core&format=json