Inhibition of Lon blocks cell proliferation, enhances chemosensitivity by promoting apoptosis and decreases cellular bioenergetics of bladder cancer: potential roles of Lon as a prognostic marker and therapeutic target in baldder cancer (Q34957287)

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English	Inhibition of Lon blocks cell proliferation, enhances chemosensitivity by promoting apoptosis and decreases cellular bioenergetics of bladder cancer: potential roles of Lon as a prognostic marker and therapeutic target in baldder cancer	scientific article

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5 August 2017

Inhibition of Lon blocks cell proliferation, enhances chemosensitivity by promoting apoptosis and decreases cellular bioenergetics of bladder cancer: potential roles of Lon as a prognostic marker and therapeutic target in baldder cancer (English)

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5 August 2017

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12 June 2020

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Yongzhang Liu

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12 June 2020

Kate Huang

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12 June 2020

Rongrong Wang

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12 June 2020

Cuicui Xu

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12 June 2020

Yang Shi

6

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12 June 2020

Xiaoyi Wu

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12 June 2020

Zhi Wu

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12 June 2020

Jiliang Zhang

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12 June 2020

Lin Chen

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12 June 2020

Lu Wang

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12 June 2020

Xiaomin Yu

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12 June 2020

Haibo Zhu

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12 June 2020

Bin Lu

14

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12 June 2020

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1 November 2014

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5 August 2017

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12 June 2020

5

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12 June 2020

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12 June 2020

11209-11224

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12 June 2020

Down-regulating overexpressed human Lon in cervical cancer suppresses cell proliferation and bioenergetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Upregulation of the mitochondrial Lon Protease allows adaptation to acute oxidative stress but dysregulation is associated with chronic stress, disease, and aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Mitochondrial matrix proteases as novel therapeutic targets in malignancy.

1 reference

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8 July 2018

Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents.

1 reference

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8 July 2018

Phosphorylation of human TFAM in mitochondria impairs DNA binding and promotes degradation by the AAA+ Lon protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives

1 reference

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8 July 2018

Multitasking in the mitochondrion by the ATP-dependent Lon protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Impairment of lon-induced protection against the accumulation of oxidized proteins in senescent wi-38 fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Mitochondrial proteases and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Functional characterization of the promoter of the human Lon protease gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Targeting the dynamic HSP90 complex in cancer

1 reference

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8 July 2018

Cancer statistics, 2010

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8 July 2018

Upregulation of nuclear-encoded mitochondrial LON protease in HAART-treated HIV-positive patients with lipodystrophy: implications for the pathogenesis of the disease

1 reference

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8 July 2018

Pathological roles of MAPK signaling pathways in human diseases

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8 July 2018

A small molecule inhibitor of inducible heat shock protein 70.

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8 July 2018

Expression of Bmi-1 is a prognostic marker in bladder cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Biomarkers for detection and surveillance of bladder cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Functional mechanics of the ATP-dependent Lon protease- lessons from endogenous protein and synthetic peptide substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

The layered structure of human mitochondrial DNA nucleoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Turnover of mitochondrial steroidogenic acute regulatory (StAR) protein by Lon protease: the unexpected effect of proteasome inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells

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8 July 2018

Clinical model of lifetime cost of treating bladder cancer and associated complications

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8 July 2018

Biological roles of the Lon ATP-dependent protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

The health economics of bladder cancer: a comprehensive review of the published literature.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

DNA and RNA binding by the mitochondrial lon protease is regulated by nucleotide and protein substrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Urinary markers of bladder carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

The ATP-dependent Lon protease of Mus musculus is a DNA-binding protein that is functionally conserved between yeast and mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Effect of cytochrome c on the generation and elimination of O2*- and H2O2 in mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease

1 reference

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8 July 2018

Enhanced mitochondrial biogenesis is associated with increased expression of the mitochondrial ATP-dependent Lon protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

8 July 2018

The human LON protease binds to mitochondrial promoters in a single-stranded, site-specific, strand-specific manner

1 reference

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8 July 2018

Tobacco and bladder cancer in males: increased risk for inhalers and smokers of black tobacco

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8 July 2018

Survivin expression quantified by Image Pro-Plus compared with visual assessment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4294382

26 October 2018

The protein expression of TRP-1 and galectin-1 in cutaneous malignant melanomas.

1 reference

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26 October 2018

Microarrays of bladder cancer tissue are highly representative of proliferation index and histological grade

1 reference

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26 October 2018

[Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue]

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12 December 2020

based on heuristic

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[Effect of RNA interference for Lon gene silencing on growth and apoptosis of human breast cancer MCF7 cells]

1 reference

https://pubmed.ncbi.nlm.nih.gov/25526030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitivity of human complement factor H related protein (BTA stat) test and voided urine cytology in the diagnosis of bladder cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25526030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of the mitochondrial Pim1/Lon protease in yeast results in accelerated aging and impairment of the proteasome

1 reference

https://pubmed.ncbi.nlm.nih.gov/25526030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.18632/ONCOTARGET.2026

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12 June 2020

PMC publication ID

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12 June 2020

PubMed publication ID

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Europe PubMed Central

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12 June 2020

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